Approaches to improve the biocompatibility and systemic circulation of inorganic porous nanoparticles

Delivery of miR-375 and doxorubicin hydrochloride by lipid-coated hollow mesoporous silica nanoparticles to overcome multiple drug resistance in hepatocellular carcinoma

(2017) Huiying Xue et al.   International Journal of Nanomedicine

EpCAM aptamer-functionalized polydopamine-coated mesoporous silica nanoparticles loaded with DM1 for targeted therapy in colorectal cancer

(2017) Yang Li et al.   International Journal of Nanomedicine

RGD conjugated liposome-hollow silica hybrid nanovehicles for targeted and controlled delivery of arsenic trioxide against hepatic carcinoma

(2017) Weidong Fei et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Core-interlayer-shell Fe 3 O 4 @mSiO 2 @lipid-PEG-methotrexate nanoparticle for multimodal imaging and multistage targeted chemo-photodynamic therapy

(2017) Guihua Liu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Lipid Bilayer-Gated Mesoporous Silica Nanocarriers for Tumor-Targeted Delivery of Zoledronic Acid in Vivo

(2017) Diti Desai et al.   MOLECULAR PHARMACEUTICS

Mesoporous nanocarriers with a stimulus-responsive cyclodextrin gatekeeper for targeting tumor hypoxia

(2017) Jeonghun Lee et al.   Nanoscale

Quantitative and correlative biodistribution analysis of 89Zr-labeled mesoporous silica nanoparticles intravenously injected into tumor-bearing mice

(2017) Larissa Kramer et al.   Nanoscale

A smart pH-responsive nano-carrier as a drug delivery system for the targeted delivery of ursolic acid: suppresses cancer growth and metastasis by modulating P53/MMP-9/PTEN/CD44 mediated multiple signaling pathways

(2017) Kai Jiang et al.   Nanoscale

Multi-step encapsulation of chemotherapy and gene silencing agents in functionalized mesoporous silica nanoparticles

(2017) Jianliang Shen et al.   Nanoscale

Multifunctional halloysite nanotubes for targeted delivery and controlled release of doxorubicin in-vitro and in-vivo studies

(2017) Yuwei Hu et al.   NANOTECHNOLOGY

TPGS-Functionalized Polydopamine-Modified Mesoporous Silica as Drug Nanocarriers for Enhanced Lung Cancer Chemotherapy against Multidrug Resistance

(2017) Wei Cheng et al.   Small

Degradable Hollow Mesoporous Silicon/Carbon Nanoparticles for Photoacoustic Imaging-Guided Highly Effective Chemo-Thermal Tumor Therapy in Vitro and in Vivo

(2017) Jinfeng Zhang et al.   Theranostics

Leukocyte-mediated Delivery of Nanotherapeutics in Inflammatory and Tumor Sites

(2017) Xinyue Dong et al.   Theranostics

Enhanced Blood Suspensibility and Laser-Activated Tumor-specific Drug Release of Theranostic Mesoporous Silica Nanoparticles by Functionalizing with Erythrocyte Membranes

(2017) Jinghan Su et al.   Theranostics

Preparation and Application of Cell Membrane-Camouflaged Nanoparticles for Cancer Therapy

(2017) Yihui Zhai et al.   Theranostics

Site-specific sonocatalytic tumor suppression by chemically engineered single-crystalline mesoporous titanium dioxide sonosensitizers

(2017) Xi Wang et al.   Journal of Materials Chemistry B

A pH-dependent Antibacterial Peptide Release Nano-system Blocks Tumor Growth in vivo without Toxicity

(2017) Jing Cao et al.   Scientific Reports

Tailored Dual PEGylation of Inorganic Porous Nanocarriers for Extremely Long Blood Circulation in Vivo

(2016) Tuomo Nissinen et al.   ACS Applied Materials & Interfaces

Macrophage Cell Membrane Camouflaged Au Nanoshells for in Vivo Prolonged Circulation Life and Enhanced Cancer Photothermal Therapy

(2016) Mingjun Xuan et al.   ACS Applied Materials & Interfaces

Irinotecan Delivery by Lipid-Coated Mesoporous Silica Nanoparticles Shows Improved Efficacy and Safety over Liposomes for Pancreatic Cancer

(2016) Xiangsheng Liu et al.   ACS Nano

Mesoporous Silica Nanoparticle-Supported Lipid Bilayers (Protocells) for Active Targeting and Delivery to Individual Leukemia Cells

(2016) Paul N. Durfee et al.   ACS Nano

Cancer Cell Membrane–Biomimetic Nanoparticles for Homologous-Targeting Dual-Modal Imaging and Photothermal Therapy

(2016) Ze Chen et al.   ACS Nano

Cancer Cell Membrane-Coated Gold Nanocages with Hyperthermia-Triggered Drug Release and Homotypic Target Inhibit Growth and Metastasis of Breast Cancer

(2016) Huiping Sun et al.   ADVANCED FUNCTIONAL MATERIALS

All-in-One Theranostic Nanoplatform Based on Hollow TaOx for Chelator-Free Labeling Imaging, Drug Delivery, and Synergistically Enhanced Radiotherapy

(2016) Guosheng Song et al.   ADVANCED FUNCTIONAL MATERIALS

A Triple-Collaborative Strategy for High-Performance Tumor Therapy by Multifunctional Mesoporous Silica-Coated Gold Nanorods

(2016) Guo-Feng Luo et al.   ADVANCED FUNCTIONAL MATERIALS

Porous Silicon and Polymer Nanocomposites for Delivery of Peptide Nucleic Acids as Anti-MicroRNA Therapies

(2016) Kelsey R. Beavers et al.   ADVANCED MATERIALS

Cancer Cell Membrane-Coated Upconversion Nanoprobes for Highly Specific Tumor Imaging

(2016) Lang Rao et al.   ADVANCED MATERIALS

In vitro and in vivo assessment of heart-homing porous silicon nanoparticles

(2016) Mónica P.A. Ferreira et al.   BIOMATERIALS

Red blood cell membrane camouflaged magnetic nanoclusters for imaging-guided photothermal therapy

(2016) Xiaoqing Ren et al.   BIOMATERIALS

Rational design of multifunctional magnetic mesoporous silica nanoparticle for tumor-targeted magnetic resonance imaging and precise therapy

(2016) Wei-Hai Chen et al.   BIOMATERIALS

Hollow mesoporous silica nanoparticles facilitated drug delivery via cascade pH stimuli in tumor microenvironment for tumor therapy

(2016) Junjie Liu et al.   BIOMATERIALS

In vivo dual-targeted chemotherapy of drug resistant cancer by rationally designed nanocarrier

(2016) Yang Wang et al.   BIOMATERIALS

In vitroandin vivoevaluation of puerarin-loaded PEGylated mesoporous silica nanoparticles

(2016) Xinyi Liu et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Protein-gold clusters-capped mesoporous silica nanoparticles for high drug loading, autonomous gemcitabine/doxorubicin co-delivery, and in-vivo tumor imaging

(2016) Jonas G. Croissant et al.   JOURNAL OF CONTROLLED RELEASE

Preferential Cancer Cell Self-Recognition and Tumor Self-Targeting by Coating Nanoparticles with Homotypic Cancer Cell Membranes

(2016) Jing-Yi Zhu et al.   NANO LETTERS

Hyaluronidase-triggered anticancer drug and siRNA delivery from cascaded targeting nanoparticles for drug-resistant breast cancer therapy

(2016) Jie Ding et al.   Nano Research

Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date

(2016) Daniel Bobo et al.   PHARMACEUTICAL RESEARCH

Mesoporous Bamboo Charcoal Nanoparticles as a New Near-Infrared Responsive Drug Carrier for Imaging-Guided Chemotherapy/Photothermal Synergistic Therapy of Tumor

(2016) Xinghua Dong et al.   Advanced Healthcare Materials

Tailored mesoporous silica nanosystem with enhanced permeability of the blood–brain barrier to antagonize glioblastoma

(2016) Yuanyuan You et al.   Journal of Materials Chemistry B

Improved in vivo tumor therapy via host–guest complexation

(2016) Yong Yao et al.   Journal of Materials Chemistry B

Engineering Intrinsically Zirconium-89 Radiolabeled Self-Destructing Mesoporous Silica Nanostructures for In Vivo Biodistribution and Tumor Targeting Studies

(2016) Shreya Goel et al.   Advanced Science

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Tumor-Homing Cell-Penetrating Peptide Linked to Colloidal Mesoporous Silica Encapsulated (-)-Epigallocatechin-3-gallate as Drug Delivery System for Breast Cancer Therapy in Vivo

(2015) Jie Ding et al.   ACS Applied Materials & Interfaces

Reactive Oxygen Species-Manipulated Drug Release from a Smart Envelope-Type Mesoporous Titanium Nanovehicle for Tumor Sonodynamic-Chemotherapy

(2015) Jinjin Shi et al.   ACS Applied Materials & Interfaces

PEGylated Carbon Nanocapsule: A Universal Reactor and Carrier for In Vivo Delivery of Hydrophobic and Hydrophilic Nanoparticles

(2015) Amritha Rammohan et al.   ACS Applied Materials & Interfaces

Use of a Lipid-Coated Mesoporous Silica Nanoparticle Platform for Synergistic Gemcitabine and Paclitaxel Delivery to Human Pancreatic Cancer in Mice

(2015) Huan Meng et al.   ACS Nano

A Versatile Nanotheranostic Agent for Efficient Dual-Mode Imaging Guided Synergistic Chemo-Thermal Tumor Therapy

(2015) Xiaojun Cai et al.   ADVANCED FUNCTIONAL MATERIALS

Hyaluronic Acid Modified Tantalum Oxide Nanoparticles Conjugating Doxorubicin for Targeted Cancer Theranostics

(2015) Yushen Jin et al.   BIOCONJUGATE CHEMISTRY

Programmed packaging of mesoporous silica nanocarriers for matrix metalloprotease 2-triggered tumor targeting and release

(2015) Zhen Zou et al.   BIOMATERIALS

Phospholipid-stabilized mesoporous carbon nanospheres as versatile carriers for systemic delivery of amphiphobic SNX-2112 (a Hsp90 inhibitor) with enhanced antitumor effect

(2015) Xingwang Zhang et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Paclitaxel/gelatin coated magnetic mesoporous silica nanoparticles: Preparation and antitumor efficacy in vivo

(2015) Erxi Che et al.   MICROPOROUS AND MESOPOROUS MATERIALS

Multifunctional NaYF4:Yb, Er@mSiO2@Fe3O4-PEG nanoparticles for UCL/MR bioimaging and magnetically targeted drug delivery

(2015) Bei Liu et al.   Nanoscale

Enzyme responsive mesoporous silica nanoparticles for targeted tumor therapy in vitro and in vivo

(2015) Junjie Liu et al.   Nanoscale

Enzyme responsive drug delivery system based on mesoporous silica nanoparticles for tumor therapy in vivo

(2015) Yun Liu et al.   NANOTECHNOLOGY

Hollow Mesoporous Silica Nanocarriers with Multifunctional Capping Agents for In Vivo Cancer Imaging and Therapy

(2015) Shun Yang et al.   Small

Red Blood Cell Membrane as a Biomimetic Nanocoating for Prolonged Circulation Time and Reduced Accelerated Blood Clearance

(2015) Lang Rao et al.   Small

Macrophage Cell Membrane Camouflaged Mesoporous Silica Nanocapsules for In Vivo Cancer Therapy

(2015) Minjun Xuan et al.   Advanced Healthcare Materials

Effect of pH-Responsive Alginate/Chitosan Multilayers Coating on Delivery Efficiency, Cellular Uptake and Biodistribution of Mesoporous Silica Nanoparticles Based Nanocarriers

(2014) Wei Feng et al.   ACS Applied Materials & Interfaces

Erythrocyte Membrane Is an Alternative Coating to Polyethylene Glycol for Prolonging the Circulation Lifetime of Gold Nanocages for Photothermal Therapy

(2014) Ji-Gang Piao et al.   ACS Nano

Prostate stem cell antigen antibody-conjugated multiwalled carbon nanotubes for targeted ultrasound imaging and drug delivery

(2014) Huixia Wu et al.   BIOMATERIALS

A Nanostopper Approach To Selectively Engineer the Surfaces of Mesoporous Silicon

(2014) Wujun Xu et al.   CHEMISTRY OF MATERIALS

Synthesis, characterization and application of gold nanoshells using mesoporous silica core

(2014) Nihal Elbialy et al.   MICROPOROUS AND MESOPOROUS MATERIALS

Functional Nanovalves on Protein-Coated Nanoparticles for In vitro and In vivo Controlled Drug Delivery

(2014) Angela A. Hwang et al.   Small

Enhanced tumor targetability of PEGylated mesoporous silica nanoparticles on in vivo optical imaging according to their size

(2014) Hye Lan Kim et al.   RSC Advances

Mesoporous Magnetic Gold “Nanoclusters” as Theranostic Carrier for Chemo-Photothermal Co-therapy of Breast Cancer

(2014) JinRong Peng et al.   Theranostics

Engineered Stealth Porous Silicon Nanoparticles via Surface Encapsulation of Bovine Serum Albumin for Prolonging Blood Circulation in Vivo

(2013) Bing Xia et al.   ACS Applied Materials & Interfaces

In Vivo Tumor Targeting and Image-Guided Drug Delivery with Antibody-Conjugated, Radiolabeled Mesoporous Silica Nanoparticles

(2013) Feng Chen et al.   ACS Nano

Tethered Lipid Bilayer Gates: Toward Extended Retention of Hydrophilic Cargo in Porous Nanocarriers

(2013) Jixi Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

Biocompatible, Uniform, and Redispersible Mesoporous Silica Nanoparticles for Cancer-Targeted Drug Delivery In Vivo

(2013) Quan Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

Tumour homing peptide-functionalized porous silicon nanovectors for cancer therapy

(2013) Päivi J. Kinnari et al.   BIOMATERIALS

The Thiol-Michael Addition Click Reaction: A Powerful and Widely Used Tool in Materials Chemistry

(2013) Devatha P. Nair et al.   CHEMISTRY OF MATERIALS

In vivo distribution and antitumor activity of doxorubicin-loaded N-isopropylacrylamide-co-methacrylic acid coated mesoporous silica nanoparticles and safety evaluation

(2013) Yanzuo Chen et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The accelerated blood clearance (ABC) phenomenon: Clinical challenge and approaches to manage

(2013) Amr S. Abu Lila et al.   JOURNAL OF CONTROLLED RELEASE

Gelatin–mesoporous silica nanoparticles as matrix metalloproteinases-degradable drug delivery systems in vivo

(2013) Jun-Hua Xu et al.   MICROPOROUS AND MESOPOROUS MATERIALS

Minimal "Self" Peptides That Inhibit Phagocytic Clearance and Enhance Delivery of Nanoparticles

(2013) P. L. Rodriguez et al.   SCIENCE

Biocompatibility of engineered nanoparticles for drug delivery

(2012) Sheva Naahidi et al.   JOURNAL OF CONTROLLED RELEASE

A multifunctional mesoporous nanocontainer with an iron oxide core and a cyclodextrin gatekeeper for an efficient theranostic platform

(2012) Jeonghun Lee et al.   JOURNAL OF MATERIALS CHEMISTRY

Intravenous Delivery of Hydrophobin-Functionalized Porous Silicon Nanoparticles: Stability, Plasma Protein Adsorption and Biodistribution

(2012) Mirkka Sarparanta et al.   MOLECULAR PHARMACEUTICS

Raise standards for preclinical cancer research

(2012) C. Glenn Begley et al.   NATURE

Synthetic nanoparticles functionalized with biomimetic leukocyte membranes possess cell-like functions

(2012) Alessandro Parodi et al.   Nature Nanotechnology

Terminology for biorelated polymers and applications (IUPAC Recommendations 2012)

(2012) Michel Vert et al.   PURE AND APPLIED CHEMISTRY

Immune responses of therapeutic lipid nanoparticles

(2012) Weihsu Claire Chen et al.   Nanotechnology Reviews

Recent Advances in Nonviral Vectors for Gene Delivery

(2011) Xia Guo et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Shape Effect of Mesoporous Silica Nanoparticles on Biodistribution, Clearance, and Biocompatibility in Vivo

(2011) Xinglu Huang et al.   ACS Nano

Particle size-dependent and surface charge-dependent biodistribution of gold nanoparticles after intravenous administration

(2011) Stephanie Hirn et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform

(2011) C.-M. J. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian cell transfection: the present and the future

(2010) Tae Kyung Kim et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Sustained Small Interfering RNA Delivery by Mesoporous Silicon Particles

(2010) Takemi Tanaka et al.   CANCER RESEARCH

In vivo Biodistribution and Urinary Excretion of Mesoporous Silica Nanoparticles: Effects of Particle Size and PEGylation

(2010) Qianjun He et al.   Small

Targeted Killing of Cancer Cells in Vivo and in Vitro with EGF-Directed Carbon Nanotube-Based Drug Delivery

(2009) Ashwin A. Bhirde et al.   ACS Nano

Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy

(2009) Parag Aggarwal et al.   ADVANCED DRUG DELIVERY REVIEWS

Biodegradable luminescent porous silicon nanoparticles for in vivo applications

(2009) Ji-Ho Park et al.   NATURE MATERIALS

Metal free thiol–maleimide ‘Click’ reaction as a mild functionalisation strategy for degradable polymers

(2008) Ryan J. Pounder et al.   CHEMICAL COMMUNICATIONS

Improved Biocompatibility and Pharmacokinetics of Silica Nanoparticles by Means of a Lipid Coating: A Multimodality Investigation

(2008) Matti M. van Schooneveld et al.   NANO LETTERS