Mitochondria-specific photoactivation to monitor local sphingosine metabolism and function

Trifunctional lipid probes for comprehensive studies of single lipid species in living cells

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Detection of genome-edited mutant clones by a simple competition-based PCR method

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Photoswitchable diacylglycerols enable optical control of protein kinase C

(2016) James Allen Frank et al.   Nature Chemical Biology

A protocol for the systematic and quantitative measurement of protein–lipid interactions using the liposome-microarray-based assay

(2016) Antoine-Emmanuel Saliba et al.   Nature Protocols

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(2016) Xianlin Han   Nature Reviews Endocrinology

Bifunctional Sphingosine for Cell-Based Analysis of Protein-Sphingolipid Interactions

(2015) Per Haberkant et al.   ACS Chemical Biology

Enriching CRISPR-Cas9 targeted cells by co-targeting the HPRT gene

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Mitochondrially targeted redox probe reveals the variations in oxidative capacity of the haematopoietic cells

(2015) Amandeep Kaur et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Exclusive photorelease of signalling lipids at the plasma membrane

(2015) André Nadler et al.   Nature Communications

Photoswitchable fatty acids enable optical control of TRPV1

(2015) James Allen Frank et al.   Nature Communications

Lipid Cooperativity as a General Membrane-Recruitment Principle for PH Domains

(2015) Ivana Vonkova et al.   Cell Reports

Intracellular sphingosine releases calcium from lysosomes

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Systematic Screening for Novel Lipids by Shotgun Lipidomics

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A Rapidly Reversible Chemical Dimerizer System to Study Lipid Signaling in Living Cells

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Caged lipids as tools for investigating cellular signaling

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Dividing Cells Regulate Their Lipid Composition and Localization

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Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis

(2014) Aline Xavier da Silveira dos Santos et al.   MOLECULAR BIOLOGY OF THE CELL

Sphingolipid lysosomal storage disorders

(2014) Frances M. Platt   NATURE

Sphingolipid metabolites in inflammatory disease

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Easy quantitative assessment of genome editing by sequence trace decomposition

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Sphingolipid homeostasis in the web of metabolic routes

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Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids

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Genome engineering using the CRISPR-Cas9 system

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Removing endotoxin from plasmid samples by Triton X-114 isothermal extraction

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Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and Efficacy

(2012) Petr Klán et al.   CHEMICAL REVIEWS

Biochemical Membrane Lipidomics during Drosophila Development

(2012) Xue Li Guan et al.   DEVELOPMENTAL CELL

Inhibition kinetics and regulation of sphingosine kinase 1 expression in prostate cancer cells: Functional differences between sphingosine kinase 1a and 1b

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Glycosylphosphatidylinositol anchors regulate glycosphingolipid levels

(2012) Ursula Loizides-Mangold et al.   JOURNAL OF LIPID RESEARCH

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Selective Uncoupling of Individual Mitochondria within a Cell Using a Mitochondria-Targeted Photoactivated Protonophore

(2011) Susan Chalmers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration

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Differential Effects of Ceramide and Sphingosine 1-Phosphate on ERM Phosphorylation

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Activation of membrane-permeant caged PtdIns(3)P induces endosomal fusion in cells

(2010) Devaraj Subramanian et al.   Nature Chemical Biology

Functional Interactions between Sphingolipids and Sterols in Biological Membranes Regulating Cell Physiology

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Spatiotemporal control of cell signalling using a light-switchable protein interaction

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Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

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Targeting lipophilic cations to mitochondria

(2008) Michael P. Murphy   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers

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Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics

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Principles of bioactive lipid signalling: lessons from sphingolipids

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