标题
Therapeutic Approaches to Type I Interferonopathies
作者
关键词
ᅟType I interferonopathies, Autoinflammation, Therapy
出版物
Current Rheumatology Reports
Volume 20, Issue 6, Pages -
出版商
Springer Nature
发表日期
2018-04-20
DOI
10.1007/s11926-018-0743-3
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Breaching Self-Tolerance to Alu Duplex RNA Underlies MDA5-Mediated Inflammation
- (2018) Sadeem Ahmad et al. CELL
- Ruxolitinib for the treatment of patients with steroid-refractory GVHD: an introduction to the REACH trials
- (2018) Madan Jagasia et al. Immunotherapy
- JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies
- (2018) Gina A. Montealegre Sanchez et al. JOURNAL OF CLINICAL INVESTIGATION
- Tofacitinib relieves symptoms of stimulator of interferon genes (STING)–associated vasculopathy with onset in infancy caused by 2 de novo variants in TMEM173
- (2017) Jieun Seo et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Lack of Trex1 Causes Systemic Autoimmunity despite the Presence of Antiretroviral Drugs
- (2017) Martin Achleitner et al. JOURNAL OF IMMUNOLOGY
- Type I interferon-mediated autoinflammation due to DNase II deficiency
- (2017) Mathieu P. Rodero et al. Nature Communications
- Brief Report: Blockade of TANK-Binding Kinase 1/IKKɛ Inhibits Mutant Stimulator of Interferon Genes (STING)-Mediated Inflammatory Responses in Human Peripheral Blood Mononuclear Cells
- (2017) Marie-Louise Frémond et al. Arthritis & Rheumatology
- Anifrolumab, an Anti-Interferon-α Receptor Monoclonal Antibody, in Moderate-to-Severe Systemic Lupus Erythematosus
- (2017) Richard Furie et al. Arthritis & Rheumatology
- Response to: ‘JAK inhibition in STING-associated interferonopathy’ by Crowet al
- (2016) Victoria Tüngler et al. ANNALS OF THE RHEUMATIC DISEASES
- Sifalimumab, an anti-interferon-α monoclonal antibody, in moderate to severe systemic lupus erythematosus: a randomised, double-blind, placebo-controlled study
- (2016) Munther Khamashta et al. ANNALS OF THE RHEUMATIC DISEASES
- Ribonuclease H2 mutations induce a cGAS/STING‐dependent innate immune response
- (2016) Karen J Mackenzie et al. EMBO JOURNAL
- Efficacy of the Janus kinase 1/2 inhibitor ruxolitinib in the treatment of vasculopathy associated with TMEM173 -activating mutations in 3 children
- (2016) Marie-Louise Frémond et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- RNase H2 catalytic core Aicardi-Goutières syndrome–related mutant invokes cGAS–STING innate immune-sensing pathway in mice
- (2016) Vladislav Pokatayev et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Loss of Trex1 in Dendritic Cells Is Sufficient To Trigger Systemic Autoimmunity
- (2016) Katrin Peschke et al. JOURNAL OF IMMUNOLOGY
- RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA
- (2016) Christine Wolf et al. Nature Communications
- Tartrate-Resistant Acid Phosphatase Deficiency in the Predisposition to Systemic Lupus Erythematosus
- (2016) Jie An et al. Arthritis & Rheumatology
- Characterization of human disease phenotypes associated with mutations inTREX1,RNASEH2A,RNASEH2B,RNASEH2C,SAMHD1,ADAR, andIFIH1
- (2015) Yanick J. Crow et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- The JAK-STAT Pathway: Impact on Human Disease and Therapeutic Intervention
- (2015) John J. O'Shea et al. Annual Review of Medicine
- Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production
- (2015) Anja Brehm et al. JOURNAL OF CLINICAL INVESTIGATION
- Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi–Goutières Syndrome
- (2015) Elizabeth E. Gray et al. JOURNAL OF IMMUNOLOGY
- RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself
- (2015) B. J. Liddicoat et al. SCIENCE
- SAMHD1: At the Crossroads of Cell Proliferation, Immune Responses, and Virus Restriction
- (2015) Ester Ballana et al. TRENDS IN MICROBIOLOGY
- Aicardi–Goutières syndrome harbours abundant systemic and brain-reactive autoantibodies
- (2014) Eloy Cuadrado et al. ANNALS OF THE RHEUMATIC DISEASES
- Altered spatio-temporal dynamics of RNase H2 complex assembly at replication and repair sites in Aicardi–Goutières syndrome
- (2014) Barbara Kind et al. HUMAN MOLECULAR GENETICS
- Defective removal of ribonucleotides from DNA promotes systemic autoimmunity
- (2014) Claudia Günther et al. JOURNAL OF CLINICAL INVESTIGATION
- Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations
- (2014) Nadia Jeremiah et al. JOURNAL OF CLINICAL INVESTIGATION
- TREX1 Deficiency Triggers Cell-Autonomous Immunity in a cGAS-Dependent Manner
- (2014) A. Ablasser et al. JOURNAL OF IMMUNOLOGY
- Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling
- (2014) Gillian I Rice et al. NATURE GENETICS
- The ribonuclease activity of SAMHD1 is required for HIV-1 restriction
- (2014) Jeongmin Ryoo et al. NATURE MEDICINE
- Activated STING in a Vascular and Pulmonary Syndrome
- (2014) Yin Liu et al. NEW ENGLAND JOURNAL OF MEDICINE
- SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage
- (2013) R. Clifford et al. BLOOD
- Nuclease Activity of the Human SAMHD1 Protein Implicated in the Aicardi-Goutières Syndrome and HIV-1 Restriction
- (2013) Natalia Beloglazova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Single-stranded nucleic acids promote SAMHD1 complex formation
- (2013) Victoria Tüngler et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study
- (2013) Gillian I Rice et al. LANCET NEUROLOGY
- Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development
- (2012) Martin A.M. Reijns et al. CELL
- Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity
- (2012) Bjoern Hiller et al. JOURNAL OF EXPERIMENTAL MEDICINE
- RNase H2-Initiated Ribonucleotide Excision Repair
- (2012) Justin L. Sparks et al. MOLECULAR CELL
- Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature
- (2012) Gillian I Rice et al. NATURE GENETICS
- SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates
- (2012) Hichem Lahouassa et al. NATURE IMMUNOLOGY
- Type I interferonopathies: a novel set of inborn errors of immunity
- (2011) Yanick J. Crow Annals of the New York Academy of Sciences
- Mutations in proteasome subunit β type 8 cause chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature with evidence of genetic and phenotypic heterogeneity
- (2011) Yin Liu et al. ARTHRITIS AND RHEUMATISM
- Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort
- (2011) B Namjou et al. GENES AND IMMUNITY
- Aicardi-Goutières Syndrome and Systemic Lupus Erythematosus (SLE) in a 12-Year-Old Boy With SAMHD1 Mutations
- (2011) Georgia Ramantani et al. JOURNAL OF CHILD NEUROLOGY
- HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
- (2011) David C. Goldstone et al. NATURE
- An autoimmune disease prevented by anti-retroviral drugs
- (2011) Gabriele B Beck-Engeser et al. Retrovirology
- PSMB8 Encoding the β5i Proteasome Subunit Is Mutated in Joint Contractures, Muscle Atrophy, Microcytic Anemia, and Panniculitis-Induced Lipodystrophy Syndrome
- (2010) Anil K. Agarwal et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Autosomal dominant inheritance of a heterozygous mutation in SAMHD1 causing familial chilblain lupus
- (2010) Jane C. Ravenscroft et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Goutières syndrome
- (2010) Georgia Ramantani et al. ARTHRITIS AND RHEUMATISM
- The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1
- (2010) Nan Yan et al. NATURE IMMUNOLOGY
- Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response
- (2009) Gillian I Rice et al. NATURE GENETICS
- Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity
- (2008) Daniel B. Stetson et al. CELL
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