The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1

Targeting early infection to prevent HIV-1 mucosal transmission

(2010) Ashley T. Haase   NATURE

The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a β-catenin-dependent pathway

(2010) Pengyuan Yang et al.   NATURE IMMUNOLOGY

RNA Polymerase III Detects Cytosolic DNA and Induces Type I Interferons through the RIG-I Pathway

(2009) Yu-Hsin Chiu et al.   CELL

Innate Immunity: Cytoplasmic DNA Sensing by the AIM2 Inflammasome

(2009) Kate Schroder et al.   CURRENT BIOLOGY

Nucleotide Sequences and Modifications That Determine RIG-I/RNA Binding and Signaling Activities

(2009) D. Uzri et al.   JOURNAL OF VIROLOGY

Ubiquitin-Regulated Recruitment of I B Kinase   to the MAVS Interferon Signaling Adapter

(2009) S. Paz et al.   MOLECULAR AND CELLULAR BIOLOGY

Chromatin-Specific Remodeling by HMGB1 and Linker Histone H1 Silences Proinflammatory Genes during Endotoxin Tolerance

(2009) M. E. Gazzar et al.   MOLECULAR AND CELLULAR BIOLOGY

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

(2009) Hideyuki Yanai et al.   NATURE

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

(2009) Hiroki Ishikawa et al.   NATURE

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III–transcribed RNA intermediate

(2009) Andrea Ablasser et al.   NATURE IMMUNOLOGY

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

(2009) W. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The SET Complex Acts as a Barrier to Autointegration of HIV-1

(2009) Nan Yan et al.   PLoS Pathogens

Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity

(2008) Daniel B. Stetson et al.   CELL

The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

(2008) Bo Zhong et al.   IMMUNITY

The TREX1 Double-stranded DNA Degradation Activity Is Defective in Dominant Mutations Associated with Autoimmune Disease

(2008) Duane A. Lehtinen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE

Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen

(2008) Abraham L. Brass et al.   SCIENCE