Interleukin 6-Mediated Endothelial Barrier Disturbances Can Be Attenuated by Blockade of the IL6 Receptor Expressed in Brain Microvascular Endothelial Cells

Roflumilast Reduces Cerebral Inflammation in a Rat Model of Experimental Subarachnoid Hemorrhage

(2017) Qingjian Wu et al.   INFLAMMATION

Autocrine release of angiopoietin-2 mediates cerebrovascular disintegration in Moyamoya disease

(2016) Kinga G Blecharz et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Intravascular Inflammation Triggers Intracerebral Activated Microglia and Contributes to Secondary Brain Injury After Experimental Subarachnoid Hemorrhage (eSAH)

(2016) Etienne Atangana et al.   Translational Stroke Research

Microglia inflict delayed brain injury after subarachnoid hemorrhage

(2015) Ulf C. Schneider et al.   ACTA NEUROPATHOLOGICA

Tumour necrosis factor-α-mediated disruption of cerebrovascular endothelial barrier integrityin vitroinvolves the production of proinflammatory interleukin-6

(2015) Keith D. Rochfort et al.   JOURNAL OF NEUROCHEMISTRY

Mouse cerebral magnetic resonance imaging fails to visualize brain volume changes after experimental subarachnoid hemorrhage

(2014) Etienne N. Atangana et al.   ACTA NEUROCHIRURGICA

Immune-Induced Fever Is Mediated by IL-6 Receptors on Brain Endothelial Cells Coupled to STAT3-Dependent Induction of Brain Endothelial Prostaglandin Synthesis

(2014) A. Eskilsson et al.   JOURNAL OF NEUROSCIENCE

Downregulation of Blood-Brain Barrier Phenotype by Proinflammatory Cytokines Involves NADPH Oxidase-Dependent ROS Generation: Consequences for Interendothelial Adherens and Tight Junctions

(2014) Keith D. Rochfort et al.   PLoS One

Small molecules targeting JAKs--a new approach in the treatment of rheumatoid arthritis

(2013) E. Feist et al.   RHEUMATOLOGY

Novel genetically-humanized mouse model established to evaluate efficacy of therapeutic agents to human interleukin-6 receptor

(2013) Otoya Ueda et al.   Scientific Reports

Overview and introduction: The blood-brain barrier in health and disease

(2012) N. Joan Abbott et al.   EPILEPSIA

Sodium Caprate Transiently Opens Claudin-5-Containing Barriers at Tight Junctions of Epithelial and Endothelial Cells

(2012) G. Del Vecchio et al.   MOLECULAR PHARMACEUTICS

Blockade of Interleukin-6 Receptor Alleviates Disease in Mouse Model of Scleroderma

(2011) Shun Kitaba et al.   AMERICAN JOURNAL OF PATHOLOGY

Tight Junctions in Brain Barriers During Central Nervous System Inflammation

(2011) Caroline Coisne et al.   ANTIOXIDANTS & REDOX SIGNALING

Stabilization of brain microvascular endothelial barrier function by shear stress involves VE-cadherin signaling leading to modulation of pTyr-occludin levels

(2011) Tony G. Walsh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Antibody against interleukin-6 receptor attenuates left ventricular remodelling after myocardial infarction in mice

(2010) M. Kobara et al.   CARDIOVASCULAR RESEARCH

Relevance of Cerebral Interleukin-6 After Aneurysmal Subarachnoid Hemorrhage

(2010) Asita Sarrafzadeh et al.   Neurocritical Care

The molecular basis of the blood brain barrier differentiation and maintenance. Is it still a mystery?

(2010) Roberta Paolinelli et al.   PHARMACOLOGICAL RESEARCH

Inhibition of interleukin-6 receptor directly blocks osteoclast formation in vitro and in vivo

(2009) Roland Axmann et al.   ARTHRITIS AND RHEUMATISM

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

High ICP as trigger of proinflammatory IL-6 cytokine activation in aneurysmal subarachnoid hemorrhage

(2009) Daniela Graetz et al.   NEUROLOGICAL RESEARCH

Glucocorticoids Increase VE-Cadherin Expression and Cause Cytoskeletal Rearrangements in Murine Brain Endothelial cEND Cells

(2008) Kinga G Blecharz et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Differential effects of hydrocortisone and TNFα on tight junction proteins in anin vitromodel of the human blood-brain barrier

(2008) Carola Förster et al.   JOURNAL OF PHYSIOLOGY-LONDON