Chitosan in Non-Viral Gene Delivery: Role of Structure, Characterization Methods, and Insights in Cancer and Rare Diseases Therapies

Biopolymer-Based Nanoparticles for Cystic Fibrosis Lung Gene Therapy Studies

(2018) Elena Fernández Fernández et al.   Materials

Developing gene and cell therapies for rare diseases: an opportunity for synergy between academia and industry

(2017) F Mavilio   GENE THERAPY

Biodegradable nano-polymers as delivery vehicles for therapeutic small non-coding ribonucleic acids

(2017) Ahad Mokhtarzadeh et al.   JOURNAL OF CONTROLLED RELEASE

Chitosan and its derivatives: vectors in gene therapy

(2017) A S Kritchenkov et al.   RUSSIAN CHEMICAL REVIEWS

Rare Diseases: Drug Discovery and Informatics Resource

(2017) Mingzhu Zhao et al.   Interdisciplinary Sciences-Computational Life Sciences

Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair

(2017) Kunwoo Lee et al.   Nature Biomedical Engineering

DNA/chitosan electrostatic complex

(2016) Lourdes Mónica Bravo-Anaya et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Chitosan as a non-viral co-transfection system in a cystic fibrosis cell line

(2016) Elena Fernández Fernández et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Gene therapy for metachromatic leukodystrophy

(2016) Jonathan B. Rosenberg et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cystic fibrosis

(2016) J Stuart Elborn   LANCET

715. Giant Axonal Neuropathy - The Role of Natural History Studies in Gene Transfer Therapy Trial Design

(2016) Diana Bharucha-Goebel et al.   MOLECULAR THERAPY

Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo

(2016) Hao Yin et al.   NATURE BIOTECHNOLOGY

Translating the genetics of cystic fibrosis to personalized medicine

(2016) Harriet Corvol et al.   Translational Research

Overcoming Gene-Delivery Hurdles: Physiological Considerations for Nonviral Vectors

(2016) Andrew B. Hill et al.   TRENDS IN BIOTECHNOLOGY

Deletion of Wiskott–Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells

(2016) Marisa A. P. Baptista et al.   Nature Communications

Gene therapy for leukodystrophy: progress, challenges and opportunities

(2016) Patrick Aubourg   Expert Opinion on Orphan Drugs

Classification of CFTR mutation classes

(2016) Fernando Augusto Lima Marson et al.   Lancet Respiratory Medicine

Cystic fibrosis: A look into the future of prenatal screening and therapy

(2015) Kevin Nishida et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Liposomes as siRNA Delivery Vectors

(2015) Sabrina Bochicchio et al.   CURRENT DRUG METABOLISM

Hydrogel nanoparticle encapsulated plasmid as a suitable gene delivery system

(2015) A. Rafiee et al.   Cytology and Genetics

Outcomes Following Gene Therapy in Patients With Severe Wiskott-Aldrich Syndrome

(2015) Salima Hacein-Bey Abina et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Efficient Delivery and Functional Expression of Transfected Modified mRNA in Human Embryonic Stem Cell-derived Retinal Pigmented Epithelial Cells

(2015) Magnus L. Hansson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma

(2015) Robert H.I. Andtbacka et al.   JOURNAL OF CLINICAL ONCOLOGY

Solid lipid nanoparticles as nucleic acid delivery system: Properties and molecular mechanisms

(2015) Marcelo B. de Jesus et al.   JOURNAL OF CONTROLLED RELEASE

Lipid nanoparticle delivery of a microRNA-145 inhibitor improves experimental pulmonary hypertension

(2015) Jared M. McLendon et al.   JOURNAL OF CONTROLLED RELEASE

SYBR Gold Fluorescence Quenching is a Sensitive Probe of Chitosan-microRNA Interactions

(2015) Beatriz Santos-Carballal et al.   JOURNAL OF FLUORESCENCE

Synthesis of Polysaccharide-Block-Polypeptide Copolymer for Potential Co-Delivery of Drug and Plasmid DNA

(2015) Qianqian Li et al.   MACROMOLECULAR BIOSCIENCE

Cationic Lipophosphoramidates Containing a Hydroxylated Polar Headgroup for Improving Gene Delivery

(2015) Mathieu Berchel et al.   MOLECULAR PHARMACEUTICS

15. Development of Intrathecal scAAV9 Gene Therapy for Giant Axonal Neuropathy

(2015) Rachel M. Bailey et al.   MOLECULAR THERAPY

Lumacaftor–Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR

(2015) Claire E. Wainwright et al.   NEW ENGLAND JOURNAL OF MEDICINE

Stability, Intracellular Delivery, and Release of siRNA from Chitosan Nanoparticles Using Different Cross-Linkers

(2015) Maria Abdul Ghafoor Raja et al.   PLoS One

Functionalized chitosan derivatives as nonviral vectors: physicochemical properties of acylated N,N,N-trimethyl chitosan/oligonucleotide nanopolyplexes

(2015) Joyce C. C. Santos et al.   Soft Matter

Physicochemical and biological characterization of chitosan-microRNA nanocomplexes for gene delivery to MCF-7 breast cancer cells

(2015) B. Santos-Carballal et al.   Scientific Reports

A new phase of CFTR treatment for cystic fibrosis?

(2015) Scott C Bell   Lancet Respiratory Medicine

Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial

(2015) Eric W F W Alton et al.   Lancet Respiratory Medicine

Emerging aerosol drug delivery strategies: From bench to clinic

(2014) Bruce K. Rubin et al.   ADVANCED DRUG DELIVERY REVIEWS

Liposomal siRNA nanocarriers for cancer therapy

(2014) Bulent Ozpolat et al.   ADVANCED DRUG DELIVERY REVIEWS

Gene therapy in cystic fibrosis

(2014) D. K. Armstrong et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Digital Holographic Microscopy: A Quantitative Label-Free Microscopy Technique for Phenotypic Screening

(2014) Benjamin Rappaz et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

(2014) S. Kim et al.   GENOME RESEARCH

Cystic fibrosis: Toward personalized therapies

(2014) Pauline T. Ikpa et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Electrotransfection and Lipofection Show Comparable Efficiency for In Vitro Gene Delivery of Primary Human Myoblasts

(2014) Tomaz Mars et al.   JOURNAL OF MEMBRANE BIOLOGY

Translating chitosan to clinical delivery of nucleic acid-based drugs

(2014) Carla Pereira Gomes et al.   MRS BULLETIN

Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia

(2014) Julia Wallmeier et al.   NATURE GENETICS

mRNA-based therapeutics — developing a new class of drugs

(2014) Ugur Sahin et al.   NATURE REVIEWS DRUG DISCOVERY

Non-viral vectors for gene-based therapy

(2014) Hao Yin et al.   NATURE REVIEWS GENETICS

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Quantitative Stain-Free and Continuous Multimodal Monitoring of Wound Healing In Vitro with Digital Holographic Microscopy

(2014) Dominik Bettenworth et al.   PLoS One

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

Gene Therapy for Wiskott-Aldrich Syndrome--Long-Term Efficacy and Genotoxicity

(2014) C. J. Braun et al.   Science Translational Medicine

Delivery of genes into the CF airway

(2014) Deborah R Gill et al.   THORAX

MCIDAS mutations result in a mucociliary clearance disorder with reduced generation of multiple motile cilia

(2014) Mieke Boon et al.   Nature Communications

Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers

(2014) Lian Jin et al.   Theranostics

Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery

(2014) Steven Lin et al.   eLife

Comparative Efficacy and Safety of Multiple Routes of Direct CNS Administration of Adeno-Associated Virus Gene Transfer Vector Serotype rh.10 Expressing the Human Arylsulfatase A cDNA to Nonhuman Primates

(2014) Jonathan B. Rosenberg et al.   Human Gene Therapy Clinical Development

Effect of Polyplex Morphology on Cellular Uptake, Intracellular Trafficking, and Transgene Expression

(2013) Julie Shi et al.   ACS Nano

RETRACTED: Chitosan tripolyphosphate (CS/TPP) nanoparticles: Preparation, characterization and application for gene delivery in shrimp

(2013) S. Vimal et al.   ACTA TROPICA

Polysaccharide-based nucleic acid nanoformulations

(2013) Koen Raemdonck et al.   ADVANCED DRUG DELIVERY REVIEWS

Chitosans for delivery of nucleic acids

(2013) Michael D. Buschmann et al.   ADVANCED DRUG DELIVERY REVIEWS

Efficient delivery of RNA interference oligonucleotides to polarized airway epithelia in vitro

(2013) Shyam Ramachandran et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Neutrophil in Chronic Obstructive Pulmonary Disease. Too Little, Too Late or Too Much, Too Soon?

(2013) Kim Hoenderdos et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Efficient Dendrimer–DNA Complexation and Gene Delivery Vector Properties of Nitrogen-Core Poly(propyl ether imine) Dendrimer in Mammalian Cells

(2013) Abirami Lakshminarayanan et al.   BIOCONJUGATE CHEMISTRY

Ionization Behavior of Chitosan and Chitosan–DNA Polyplexes Indicate That Chitosan Has a Similar Capability to Induce a Proton-Sponge Effect as PEI

(2013) Isabelle Richard et al.   BIOMACROMOLECULES

Sildenafil Acts as Potentiator and Corrector of CFTR but Might be not Suitable for the Treatment of CF Lung Disease

(2013) Geraldine Leier et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Chitosan–DNA complexes: Effect of molecular parameters on the efficiency of delivery

(2013) Federico Bordi et al.   COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS

Chitosan–DNA complexes: Charge inversion and DNA condensation

(2013) Francesca Amaduzzi et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Chitosan-based nanoparticles for in vivo delivery of interfering agents including siRNA

(2013) Christine Vauthier et al.   CURRENT OPINION IN COLLOID & INTERFACE SCIENCE

Expert opinion in biological therapy: update on developments in lung gene transfer

(2013) Uta Griesenbach et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

MicroRNA miR-145 inhibits proliferation, invasiveness, and stem cell phenotype of an in vitro endometriosis model by targeting multiple cytoskeletal elements and pluripotency factors

(2013) Marlene Adammek et al.   FERTILITY AND STERILITY

Moving forward: cystic fibrosis gene therapy

(2013) U. Griesenbach et al.   HUMAN MOLECULAR GENETICS

Targeting miRNA-based medicines to cystic fibrosis airway epithelial cells using nanotechnology

(2013) Sally-Ann Cryan et al.   International Journal of Nanomedicine

Chitosan-based siRNA delivery systems

(2013) Héloïse Ragelle et al.   JOURNAL OF CONTROLLED RELEASE

Cystic fibrosis transmembrane conductance regulator-mRNA delivery: a novel alternative for cystic fibrosis gene therapy

(2013) Nadine Bangel-Ruland et al.   JOURNAL OF GENE MEDICINE

Overcoming Nonviral Gene Delivery Barriers: Perspective and Future

(2013) Charles H. Jones et al.   MOLECULAR PHARMACEUTICS

Detection of Phospho-Sites Generated by Protein Kinase CK2 in CFTR: Mechanistic Aspects of Thr1471 Phosphorylation

(2013) Andrea Venerando et al.   PLoS One

Regulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions

(2013) Z. Bozoky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Smelling the roses and seeing the light: gene therapy for ciliopathies

(2013) Jeremy C. McIntyre et al.   TRENDS IN BIOTECHNOLOGY

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

(2013) Thomas Gaj et al.   TRENDS IN BIOTECHNOLOGY

Parkinson's Disease: Gene Therapies

(2013) P. G. Coune et al.   Cold Spring Harbor Perspectives in Medicine

Personalized Medicine in Cystic Fibrosis

(2012) John P. Clancy et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Protein analysis by dynamic light scattering: Methods and techniques for students

(2012) Bernard Lorber et al.   BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION

Engineered nonviral nanocarriers for intracellular gene delivery applications

(2012) Isaac Ojea-Jiménez et al.   Biomedical Materials

Circular Dichroism Spectroscopy of DNA: From Duplexes to Quadruplexes

(2012) Michaela Vorlíčková et al.   CHIRALITY

Chitosan–hyaluronic acid nanoparticles for gene silencing: The role of hyaluronic acid on the nanoparticles’ formation and activity

(2012) Sonia Al-Qadi et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Progress in Gene and Cell Therapy for Cystic Fibrosis Lung Disease

(2012) Uta Griesenbach et al.   CURRENT PHARMACEUTICAL DESIGN

Correction of Brain Oligodendrocytes by AAVrh.10 Intracerebral Gene Therapy in Metachromatic Leukodystrophy Mice

(2012) Françoise Piguet et al.   HUMAN GENE THERAPY

Conformational Changes in DNA upon Ligand Binding Monitored by Circular Dichroism

(2012) Yu-Ming Chang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Degradable copolymer based on amphiphilic N-octyl-N-quatenary chitosan and low-molecular weight polyethylenimine for gene delivery

(2012) Qing Zhu et al.   International Journal of Nanomedicine

Use of confocal microscopy for nanoparticle drug delivery through skin

(2012) Leshuai W. Zhang et al.   JOURNAL OF BIOMEDICAL OPTICS

Ivacaftor potentiation of multiple CFTR channels with gating mutations

(2012) Haihui Yu et al.   Journal of Cystic Fibrosis

Innate immunity in cystic fibrosis lung disease

(2012) D. Hartl et al.   Journal of Cystic Fibrosis

MicroRNA and cancer

(2012) Martin D. Jansson et al.   Molecular Oncology

Cell-penetrating Peptides as Versatile Vehicles for Oligonucleotide Delivery

(2012) Helerin Margus et al.   MOLECULAR THERAPY

Advances in Cell and Gene-based Therapies for Cystic Fibrosis Lung Disease

(2012) Mayumi Oakland et al.   MOLECULAR THERAPY

Increased Erythropoiesis in Mice Injected With Submicrogram Quantities of Pseudouridine-containing mRNA Encoding Erythropoietin

(2012) Katalin Karikó et al.   MOLECULAR THERAPY

The Possible “Proton Sponge ” Effect of Polyethylenimine (PEI) Does Not Include Change in Lysosomal pH

(2012) Rikke V Benjaminsen et al.   MOLECULAR THERAPY

Rare diseases and orphan drugs

(2012) Irena Melnikova   NATURE REVIEWS DRUG DISCOVERY

Magnetized Aerosols Comprising Superparamagnetic Iron Oxide Nanoparticles Improve Targeted Drug and Gene Delivery to the Lung

(2012) Guenther Hasenpusch et al.   PHARMACEUTICAL RESEARCH

SPR evaluation of binding kinetics and affinity study of modified RNA aptamers towards small molecules

(2012) Eva González-Fernández et al.   TALANTA

Hypertonic Saline in Treatment of Pulmonary Disease in Cystic Fibrosis

(2012) Emer P. Reeves et al.   TheScientificWorldJOURNAL

Gene therapy in cystic fibrosis

(2012) Michelle Prickett et al.   Translational Research

Long-Term Expression and Safety of Administration of AAVrh.10hCLN2 to the Brain of Rats and Nonhuman Primates for the Treatment of Late Infantile Neuronal Ceroid Lipofuscinosis

(2012) Dolan Sondhi et al.   Human Gene Therapy Methods

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Development and characterization of a new plasmid delivery system based on chitosan–sodium deoxycholate nanoparticles

(2011) A. Cadete et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Dry powder aerosols of polyethylenimine (PEI)-based gene vectors mediate efficient gene delivery to the lung

(2011) Corinna Pfeifer et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticle mediated delivery of pure P53 supercoiled plasmid DNA for gene therapy

(2011) Vítor M. Gaspar et al.   JOURNAL OF CONTROLLED RELEASE

Biophysical properties of chitosan/siRNA polyplexes: Profiling the polymer/siRNA interactions and bioactivity

(2011) Pascale Holzerny et al.   JOURNAL OF CONTROLLED RELEASE

Therapeutic plasmid DNA versus siRNA delivery: Common and different tasks for synthetic carriers

(2011) Claudia Scholz et al.   JOURNAL OF CONTROLLED RELEASE

Gene and cell therapy for cystic fibrosis: From bench to bedside

(2011) Massimo Conese et al.   Journal of Cystic Fibrosis

State-of-the-art gene-based therapies: the road ahead

(2011) Mark A. Kay   NATURE REVIEWS GENETICS

Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809

(2011) F. Van Goor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ataluren (PTC124) Induces Cystic Fibrosis Transmembrane Conductance Regulator Protein Expression and Activity in Children with Nonsense Mutation Cystic Fibrosis

(2010) Isabelle Sermet-Gaudelus et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Therapeutics Development for Cystic Fibrosis: A Successful Model for a Multisystem Genetic Disease

(2010) Melissa A. Ashlock et al.   Annual Review of Medicine

The influence of chitosan valence on the complexation and transfection of DNA: The weaker the DNA–chitosan binding the higher the transfection efficiency

(2010) Manuel Alatorre-Meda et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Chemical vectors for gene delivery: uptake and intracellular trafficking

(2010) Chantal Pichon et al.   CURRENT OPINION IN BIOTECHNOLOGY

DNA vaccines for targeting bacterial infections

(2010) Mariana Ingolotti et al.   Expert Review of Vaccines

Validation of recombinant Sendai virus in a non-natural host model

(2010) U Griesenbach et al.   GENE THERAPY

Chitosan as a carrier for targeted delivery of small interfering RNA

(2010) Walter E. Rudzinski et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Anwendung der statischen und dynamischen Lichtstreuung – Eine Übersicht

(2010) F. Fankhauser II   KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE

Intracellular Trafficking and Decondensation Kinetics of Chitosan–pDNA Polyplexes

(2010) Marc Thibault et al.   MOLECULAR THERAPY

miR-145-dependent targeting of Junctional Adhesion Molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness

(2010) M Götte et al.   ONCOGENE

Human MicroRNA Oncogenes and Tumor Suppressors Show Significantly Different Biological Patterns: From Functions to Targets

(2010) Dong Wang et al.   PLoS One

Fatty acid metabolism in cystic fibrosis

(2010) Birgitta Strandvik   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Theory and Applications of Surface Plasmon Resonance, Resonant Mirror, Resonant Waveguide Grating, and Dual Polarization Interferometry Biosensors

(2010) Hikmat N. Daghestani et al.   SENSORS

Principles and techniques of digital holographic microscopy

(2010) Myung K. Kim   Journal of Photonics for Energy

Chitosan-based formulations for delivery of DNA and siRNA

(2009) Shirui Mao et al.   ADVANCED DRUG DELIVERY REVIEWS

Characterizing DNA Condensation by Structurally Different Chitosans of Variable Gene Transfer Efficacy

(2009) Nina K. Reitan et al.   BIOMACROMOLECULES

New Insights into Chitosan−DNA Interactions Using Isothermal Titration Microcalorimetry

(2009) Pei Lian Ma et al.   BIOMACROMOLECULES

Molecular design of chitosan gene delivery systems with an optimized balance between polyplex stability and polyplex unpacking

(2009) Sabina P. Strand et al.   BIOMATERIALS

MicroRNA function in cancer: oncogene or a tumor suppressor?

(2009) Sylvia K. Shenouda et al.   CANCER AND METASTASIS REVIEWS

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

Circular Dichroism Techniques: Biomolecular and Nanostructural Analyses- A Review

(2009) Bijan Ranjbar et al.   Chemical Biology & Drug Design

Ultrafine chitosan nanoparticles as an efficient nucleic acid delivery system targeting neuronal cells

(2009) Meenakshi Malhotra et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Ionically crosslinked chitosan/tripolyphosphate nanoparticles for oligonucleotide and plasmid DNA delivery

(2009) Noemi Csaba et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Inhaled medication and inhalation devices for lung disease in patients with cystic fibrosis: A European consensus

(2009) Harry Heijerman et al.   Journal of Cystic Fibrosis

Specific inhibition of epithelial Na+channels by antisense oligonucleotides for the treatment of Na+hyperabsorption in cystic fibrosis

(2009) Katja Sobczak et al.   JOURNAL OF GENE MEDICINE

Nonviral siRNA Delivery to the Lung: Investigation of PEG−PEI Polyplexes and Their In Vivo Performance

(2009) Olivia M. Merkel et al.   MOLECULAR PHARMACEUTICS

Circular dichroism and conformational polymorphism of DNA

(2009) J. Kypr et al.   NUCLEIC ACIDS RESEARCH

Cystic fibrosis: Exploiting its genetic basis in the hunt for new therapies

(2009) James L. Kreindler   PHARMACOLOGY & THERAPEUTICS

Nutrition in Cystic Fibrosis

(2009) Julia Matel et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

CFTR Delivery to 25% of Surface Epithelial Cells Restores Normal Rates of Mucus Transport to Human Cystic Fibrosis Airway Epithelium

(2009) Liqun Zhang et al.   PLOS BIOLOGY

Cystic fibrosis gene therapy: successes, failures and hopes for the future

(2009) Uta Griesenbach et al.   Expert Review of Respiratory Medicine

Metachromatic leukodystrophy: genetics, pathogenesis and therapeutic options

(2008) Volkmar Gieselmann   ACTA PAEDIATRICA

Efficient construction of therapeutics, bioconjugates, biomaterials and bioactive surfaces using azide–alkyne “click” chemistry☆

(2008) J LUTZ et al.   ADVANCED DRUG DELIVERY REVIEWS

Functional Properties of Mixed Cystic Fibrosis and Normal Bronchial Epithelial Cell Cultures

(2008) Luc Dannhoffer et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Efficient gene delivery using chitosan–polyethylenimine hybrid systems

(2008) Hu-Lin Jiang et al.   Biomedical Materials

Cell penetrating peptide-modified pharmaceutical nanocarriers for intracellular drug and gene delivery

(2008) Vladimir P. Torchilin   BIOPOLYMERS

Chitosan as a carrier for non-viral gene transfer in a cystic-fibrosis cell line

(2008) Per Nydert et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species

(2008) Jiří Homola   CHEMICAL REVIEWS

Nonviral Vectors for Gene Delivery

(2008) Meredith A. Mintzer et al.   CHEMICAL REVIEWS

Update on fat-soluble vitamins in cystic fibrosis

(2008) Asim Maqbool et al.   CURRENT OPINION IN PULMONARY MEDICINE

Chitosan/cyclodextrin nanoparticles can efficiently transfect the airway epithelium in vitro

(2008) Desirée Teijeiro-Osorio et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Gene transfer into guinea pig cochlea using adeno-associated virus vectors

(2008) Masaya Konishi et al.   JOURNAL OF GENE MEDICINE

Lentivirus Vector Can Be Readministered to Nasal Epithelia without Blocking Immune Responses

(2008) P. L. Sinn et al.   JOURNAL OF VIROLOGY

Evaluation of chitosan salts as non-viral gene vectors in CHO-K1 cells

(2007) W WEECHARANGSAN et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS