Characterization and clinical use of inflammatory cerebrospinal fluid protein markers in Alzheimer’s disease

Clinical validity of cerebrospinal fluid Aβ42, tau, and phospho-tau as biomarkers for Alzheimer's disease in the context of a structured 5-phase development framework

(2017) Niklas Mattsson et al.   NEUROBIOLOGY OF AGING

Metallothionein, Copper and Alpha-Synuclein in Alpha-Synucleinopathies

(2017) Yuho Okita et al.   Frontiers in Neuroscience

Evaluation of Intrathecal Serum Amyloid P (SAP) and C-Reactive Protein (CRP) Synthesis in Alzheimer's Disease with the Use of Index Values

(2017) Sandra D. Mulder et al.   JOURNAL OF ALZHEIMERS DISEASE

Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status

(2016) Laura Piccio et al.   ACTA NEUROPATHOLOGICA

Cerebrospinal fluid sTREM2 levels are associated with gray matter volume increases and reduced diffusivity in early Alzheimer's disease

(2016) Juan Domingo Gispert et al.   Alzheimers & Dementia

Neuroinflammation in Alzheimer's disease: Current evidence and future directions

(2016) Valeria Calsolaro et al.   Alzheimers & Dementia

The ASA's Statement onp-Values: Context, Process, and Purpose

(2016) Ronald L. Wasserstein et al.   AMERICAN STATISTICIAN

There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS

(2016) Aaron D. Gitler et al.   BRAIN RESEARCH

sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers

(2016) Marc Suárez‐Calvet et al.   EMBO Molecular Medicine

Targeting microglia for the treatment of Alzheimer's Disease

(2016) Paul D. Wes et al.   GLIA

Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease

(2016) Amanda Heslegrave et al.   Molecular Neurodegeneration

Multiplex analyte assays to characterize different dementias: brain inflammatory cytokines in poststroke and other dementias

(2016) Aiqing Chen et al.   NEUROBIOLOGY OF AGING

Early changes in CSF sTREM2 in dominantly inherited Alzheimers disease occur after amyloid deposition and neuronal injury

(2016) M. Suarez-Calvet et al.   Science Translational Medicine

GWAS of longitudinal amyloid accumulation on18F-florbetapir PET in Alzheimer’s disease implicates microglial activation geneIL1RAP

(2015) Vijay K Ramanan et al.   BRAIN

Sensitivity, Specificity, PPV, and NPV for Predictive Biomarkers

(2015) Richard Simon   JNCI-Journal of the National Cancer Institute

TREM2 in CNS homeostasis and neurodegenerative disease

(2015) Meghan M. Painter et al.   Molecular Neurodegeneration

Innate immunity in Alzheimer's disease

(2015) Michael T Heneka et al.   NATURE IMMUNOLOGY

TREM2 variants and risk of Alzheimer’s disease: a meta-analysis

(2015) Yanjun Lu et al.   NEUROLOGICAL SCIENCES

Monomeric C-reactive protein-a key molecule driving development of Alzheimer’s disease associated with brain ischaemia?

(2015) M. Slevin et al.   Scientific Reports

Sensitivity, Specificity, PPV, and NPV for Predictive Biomarkers

(2015) Richard Simon   JNCI-Journal of the National Cancer Institute

Phosphorylated Tau-Aβ 42 Ratio as a Continuous Trait for Biomarker Discovery for Early-Stage Alzheimer’s Disease in Multiplex Immunoassay Panels of Cerebrospinal Fluid

(2014) Oscar Harari et al.   BIOLOGICAL PSYCHIATRY

Body Fluid Cytokine Levels in Mild Cognitive Impairment and Alzheimer’s Disease: a Comparative Overview

(2014) Frederic Brosseron et al.   MOLECULAR NEUROBIOLOGY

Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias

(2014) Gary W. Beecham et al.   PLoS Genetics

Genome-Wide Association Study of CSF Levels of 59 Alzheimer's Disease Candidate Proteins: Significant Associations with Proteins Involved in Amyloid Processing and Inflammation

(2014) John S. K. Kauwe et al.   PLoS Genetics

Cerebrospinal fluid inflammatory markers in Parkinson’s disease – Associations with depression, fatigue, and cognitive impairment

(2013) Daniel Lindqvist et al.   BRAIN BEHAVIOR AND IMMUNITY

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

(2013) Chia-Chen Liu et al.   Nature Reviews Neurology

What does complement do in Alzheimer’s disease? Old molecules with new insights

(2013) Yong Shen et al.   Translational Neurodegeneration

Genome-wide Association and Population Genetic Analysis of C-Reactive Protein in African American and Hispanic American Women

(2012) Alex P. Reiner et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mrp14 Deficiency Ameliorates Amyloid   Burden by Increasing Microglial Phagocytosis and Modulation of Amyloid Precursor Protein Processing

(2012) M. P. Kummer et al.   JOURNAL OF NEUROSCIENCE

The Role of Peripheral Inflammatory Markers in Dementia and Alzheimer's Disease: A Meta-Analysis

(2012) A. Koyama et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

Amyloid Plaques Dissociate Pentameric to Monomeric C-Reactive Protein: A Novel Pathomechanism Driving Cortical Inflammation in Alzheimer's Disease?

(2011) Frederik Strang et al.   BRAIN PATHOLOGY

CRP gene variation affects early development of Alzheimer's disease-related plaques

(2011) Eloise Kok et al.   Journal of Neuroinflammation

Biomarkers: Portents of malignancy

(2011) Vicki Brower   NATURE

Promotion of β-amyloid production by C-reactive protein and its implications in the early pathogenesis of Alzheimer’s disease

(2011) Bing-Tian Bi et al.   NEUROCHEMISTRY INTERNATIONAL

A Meta-Analysis of Cytokines in Alzheimer's Disease

(2010) Walter Swardfager et al.   BIOLOGICAL PSYCHIATRY

APOE polymorphism and its effect on plasma C-reactive protein levels in a large general population sample

(2010) Jaroslav A. Hubacek et al.   HUMAN IMMUNOLOGY

Inflammatory markers in AD and MCI patients with different biomarker profiles

(2008) Alie Schuitemaker et al.   NEUROBIOLOGY OF AGING