Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms
出版年份 2018 全文链接
标题
Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms
作者
关键词
-
出版物
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 25, Issue 3, Pages 252-260
出版商
Springer Nature
发表日期
2018-02-24
DOI
10.1038/s41594-018-0037-5
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
- (2017) Shawn Q Zheng et al. NATURE METHODS
- TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
- (2016) Yuan Gao et al. NATURE
- Pore architecture of TRIC channels and insights into their gating mechanism
- (2016) Hanting Yang et al. NATURE
- Crystal structure of the epithelial calcium channel TRPV6
- (2016) Kei Saotome et al. NATURE
- Cryo-EM structure of the open high-conductance Ca2+-activated K+ channel
- (2016) Xiao Tao et al. NATURE
- Cryo-electron microscopy structure of the TRPV2 ion channel
- (2016) Lejla Zubcevic et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- TRPV4: Molecular Conductor of a Diverse Orchestra
- (2016) John P. M. White et al. PHYSIOLOGICAL REVIEWS
- Structure of the voltage-gated K+ channel Eag1 reveals an alternative voltage sensing mechanism
- (2016) J. R. Whicher et al. SCIENCE
- Structure of the full-length TRPV2 channel by cryo-EM
- (2016) Kevin W. Huynh et al. Nature Communications
- Cryo-electron microscopy structure of the TRPV2 ion channel
- (2016) Lejla Zubcevic et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The Integrity of the TRP Domain Is Pivotal for Correct TRPV1 Channel Gating
- (2015) Lucia Gregorio-Teruel et al. BIOPHYSICAL JOURNAL
- Differential mechanisms of Cantú syndrome–associated gain of function mutations in theABCC9(SUR2) subunit of the KATPchannel
- (2015) Paige E. Cooper et al. JOURNAL OF GENERAL PHYSIOLOGY
- Determinants of cation transport selectivity: Equilibrium binding and transport kinetics
- (2015) Steve W. Lockless JOURNAL OF GENERAL PHYSIOLOGY
- CTFFIND4: Fast and accurate defocus estimation from electron micrographs
- (2015) Alexis Rohou et al. JOURNAL OF STRUCTURAL BIOLOGY
- Semi-automated selection of cryo-EM particles in RELION-1.3
- (2015) Sjors H.W. Scheres JOURNAL OF STRUCTURAL BIOLOGY
- Tools for macromolecular model building and refinement into electron cryo-microscopy reconstructions
- (2015) Alan Brown et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel
- (2014) Stephen G. Brohawn et al. NATURE
- TRP Channels and Pain
- (2013) David Julius Annual Review of Cell and Developmental Biology
- The puzzle of TRPV4 channelopathies
- (2013) Bernd Nilius et al. EMBO REPORTS
- A TRPV4 Channel C-terminal Folding Recognition Domain Critical for Trafficking and Function
- (2013) Lei Lei et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Likelihood-based classification of cryo-EM images using FREALIGN
- (2013) Dmitry Lyumkis et al. JOURNAL OF STRUCTURAL BIOLOGY
- TRPV1 structures in distinct conformations reveal activation mechanisms
- (2013) Erhu Cao et al. NATURE
- Structure of the TRPV1 ion channel determined by electron cryo-microscopy
- (2013) Maofu Liao et al. NATURE
- Quantifying the local resolution of cryo-EM density maps
- (2013) Alp Kucukelbir et al. NATURE METHODS
- Importance of lipid-pore loop interface for potassium channel structure and function
- (2013) E. A. W. van der Cruijsen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sodium and potassium competition in potassium-selective and non-selective channels
- (2013) David B. Sauer et al. Nature Communications
- TRPV4-associated skeletal dysplasias
- (2012) Gen Nishimura et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS
- Structural and Biochemical Consequences of Disease-Causing Mutations in the Ankyrin Repeat Domain of the Human TRPV4 Channel
- (2012) Hitoshi Inada et al. BIOCHEMISTRY
- TRPV4 Is a Regulator of Adipose Oxidative Metabolism, Inflammation, and Energy Homeostasis
- (2012) Li Ye et al. CELL
- Selective disruption of high sensitivity heat activation but not capsaicin activation of TRPV1 channels by pore turret mutations
- (2012) Yuanyuan Cui et al. JOURNAL OF GENERAL PHYSIOLOGY
- RELION: Implementation of a Bayesian approach to cryo-EM structure determination
- (2012) Sjors H.W. Scheres JOURNAL OF STRUCTURAL BIOLOGY
- TRPV4 mutations in children with congenital distal spinal muscular atrophy
- (2012) Chiara Fiorillo et al. NEUROGENETICS
- Elementary Ca2+ Signals Through Endothelial TRPV4 Channels Regulate Vascular Function
- (2012) S. K. Sonkusare et al. SCIENCE
- Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
- (2011) F. Sievers et al. Molecular Systems Biology
- Mutations in TRPV4 cause an inherited arthropathy of hands and feet
- (2011) Shireen R Lamandé et al. NATURE GENETICS
- The transient receptor potential family of ion channels
- (2011) Bernd Nilius et al. GENOME BIOLOGY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- De novo deletion of 1q24.3-q31.2 in a patient with severe growth retardation
- (2010) Akira Nishimura et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- DominantTRPV4mutations in nonlethal and lethal metatropic dysplasia
- (2010) Natalia Camacho et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- A 3.5-nm Structure of Rat TRPV4 Cation Channel Revealed by Zernike Phase-contrast Cryoelectron Microscopy
- (2010) Hideki Shigematsu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Novel and recurrent TRPV4 mutations and their association with distinct phenotypes within the TRPV4 dysplasia family
- (2010) J. Dai et al. JOURNAL OF MEDICAL GENETICS
- Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites
- (2010) M. G. Derebe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ALINE: a WYSIWYG protein-sequence alignment editor for publication-quality alignments
- (2009) Charles Simon Bond et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Mutations in the Gene Encoding the Calcium-Permeable Ion Channel TRPV4 Produce Spondylometaphyseal Dysplasia, Kozlowski Type and Metatropic Dysplasia
- (2009) Deborah Krakow et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C
- (2009) Michaela Auer-Grumbach et al. NATURE GENETICS
- Scapuloperoneal spinal muscular atrophy and CMT2C are allelic disorders caused by alterations in TRPV4
- (2009) Han-Xiang Deng et al. NATURE GENETICS
- Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C
- (2009) Guida Landouré et al. NATURE GENETICS
- TRPV4-Mediated Calcium Influx Regulates Terminal Differentiation of Osteoclasts
- (2008) Ritsuko Masuyama et al. Cell Metabolism
- The C-terminal domain of TRPV4 is essential for plasma membrane localization
- (2008) Daniel Becker et al. MOLECULAR MEMBRANE BIOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started