Structure of the voltage-gated K+ channel Eag1 reveals an alternative voltage sensing mechanism

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structure of the voltage-gated calcium channel Cav1.1 complex

(2015) J. Wu et al.   SCIENCE

Voltage-dependent gating of KCNH potassium channels lacking a covalent link between voltage-sensing and pore domains

(2015) Éva Lörinczi et al.   Nature Communications

Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6

(2015) Timothy Grant et al.   eLife

Tools for macromolecular model building and refinement into electron cryo-microscopy reconstructions

(2015) Alan Brown et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

KV10.1 opposes activity-dependent increase in Ca2+influx into the presynaptic terminal of the parallel fibre-Purkinje cell synapse

(2014) Lena Sünke Mortensen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

(2014) April Goehring et al.   Nature Protocols

Conformation-independent structural comparison of macromolecules withProSMART

(2014) Robert A. Nicholls et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Likelihood-based classification of cryo-EM images using FREALIGN

(2013) Dmitry Lyumkis et al.   JOURNAL OF STRUCTURAL BIOLOGY

The structural mechanism of KCNH-channel regulation by the eag domain

(2013) Yoni Haitin et al.   NATURE

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

Structural, Biochemical, and Functional Characterization of the Cyclic Nucleotide Binding Homology Domain from the Mouse EAG1 Potassium Channel

(2012) Maria J. Marques-Carvalho et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of the carboxy-terminal region of a KCNH channel

(2012) Tinatin I. Brelidze et al.   NATURE

Astemizole Synergizes Calcitriol Antiproliferative Activity by Inhibiting CYP24A1 and Upregulating VDR: A Novel Approach for Breast Cancer Therapy

(2012) Janice García-Quiroz et al.   PLoS One

14-3-3θ is a Binding Partner of Rat Eag1 Potassium Channels

(2012) Po-Hao Hsu et al.   PLoS One

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A Bayesian View on Cryo-EM Structure Determination

(2011) Sjors H.W. Scheres   JOURNAL OF MOLECULAR BIOLOGY

The crystal structure of a voltage-gated sodium channel

(2011) Jian Payandeh et al.   NATURE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Mechanistic Insight into Humanether-à-go-go-related Gene (hERG) K+Channel Deactivation Gating from the Solution Structure of the EAG Domain

(2010) Frederick W. Muskett et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The potassium channel Ether a go-go is a novel prognostic factor with functional relevance in acute myeloid leukemia

(2010) Jasmin R Agarwal et al.   Molecular Cancer

A Gating Charge Transfer Center in Voltage Sensors

(2010) X. Tao et al.   SCIENCE

Absence of Direct Cyclic Nucleotide Modulation of mEAG1 and hERG1 Channels Revealed with Fluorescence and Electrophysiological Methods

(2009) Tinatin I. Brelidze et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of protein properties in living cells using nanobodies

(2009) Axel Kirchhofer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Eag1 Expression Interferes with Hypoxia Homeostasis and Induces Angiogenesis in Tumors

(2008) Bryan R. Downie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY