Structure of the full-length TRPV2 channel by cryo-EM

Cryo-electron microscopy structure of the TRPV2 ion channel

(2016) Lejla Zubcevic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-electron microscopy structure of the TRPV2 ion channel

(2016) Lejla Zubcevic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

TRP channels interaction with lipids and its implications in disease

(2015) Francisco J. Taberner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Role of the Outer Pore Domain in Transient Receptor Potential Vanilloid 1 Dynamic Permeability to Large Cations

(2015) Clare H. Munns et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emerging roles of PtdIns(4,5)P2 - beyond the plasma membrane

(2015) X. Tan et al.   JOURNAL OF CELL SCIENCE

A combined coarse-grained and all-atom simulation of TRPV1 channel gating and heat activation

(2015) Wenjun Zheng et al.   JOURNAL OF GENERAL PHYSIOLOGY

Nerve Growth Factor Regulates Transient Receptor Potential Vanilloid 2 via Extracellular Signal-Regulated Kinase Signaling To Enhance Neurite Outgrowth in Developing Neurons

(2015) Matthew R. Cohen et al.   MOLECULAR AND CELLULAR BIOLOGY

Structure of the TRPA1 ion channel suggests regulatory mechanisms

(2015) Candice E. Paulsen et al.   NATURE

Atomic structure of anthrax protective antigen pore elucidates toxin translocation

(2015) Jiansen Jiang et al.   NATURE

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

Sampling the conformational space of the catalytic subunit of human γ-secretase

(2015) Xiao-chen Bai et al.   eLife

Application of Amphipols for Structure–Functional Analysis of TRP Channels

(2014) Kevin W. Huynh et al.   JOURNAL OF MEMBRANE BIOLOGY

Amphipols for Each Season

(2014) Manuela Zoonens et al.   JOURNAL OF MEMBRANE BIOLOGY

Peripheral thermosensation in mammals

(2014) Joris Vriens et al.   NATURE REVIEWS NEUROSCIENCE

Understanding the Cellular Function of TRPV2 Channel through Generation of Specific Monoclonal Antibodies

(2014) Matthew R. Cohen et al.   PLoS One

Structural Insight into the Assembly of TRPV Channels

(2014) Kevin W. Huynh et al.   STRUCTURE

Beam-induced motion correction for sub-megadalton cryo-EM particles

(2014) Sjors HW Scheres   eLife

What do we know about the transient receptor potential vanilloid 2 (TRPV2) ion channel?

(2013) Alex Perálvarez-Marín et al.   FEBS Journal

TRPV1 structures in distinct conformations reveal activation mechanisms

(2013) Erhu Cao et al.   NATURE

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

(2013) Maofu Liao et al.   NATURE

Structural basis for Ca2+ selectivity of a voltage-gated calcium channel

(2013) Lin Tang et al.   NATURE

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

Desensitization Mechanism in Prokaryotic Ligand-gated Ion Channel

(2012) Phanindra Velisetty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Calcium Signaling

(2012) M. D. Bootman   Cold Spring Harbor Perspectives in Biology

Amphipols From A to Z*

(2011) J.-L. Popot et al.   Annual Review of Biophysics

TRP Vanilloid 2 Knock-Out Mice Are Susceptible to Perinatal Lethality But Display Normal Thermal and Mechanical Nociception

(2011) U. Park et al.   JOURNAL OF NEUROSCIENCE

TRPV3 and TRPV4 Ion Channels are Not Major Contributors to Mouse Heat Sensation

(2011) Susan M Huang et al.   Molecular Pain

The crystal structure of a voltage-gated sodium channel

(2011) Jian Payandeh et al.   NATURE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation

(2010) T. G. Banke et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Ca2+-Dependent Desensitization of TRPV2 Channels Is Mediated by Hydrolysis of Phosphatidylinositol 4,5-Bisphosphate

(2010) J. Mercado et al.   JOURNAL OF NEUROSCIENCE

Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

(2010) Pil Seok Chae et al.   NATURE METHODS

Vanilloid Transient Receptor Potential Cation Channels: An Overview

(2008) Bernd Nilius et al.   CURRENT PHARMACEUTICAL DESIGN

Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel

(2008) G. M. Clayton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA