标题
Rescue of conformational dynamics in enzyme catalysis by directed evolution
作者
关键词
-
出版物
Nature Communications
Volume 9, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-04-04
DOI
10.1038/s41467-018-03562-9
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Comprehensive analysis of NMR data using advanced line shape fitting
- (2017) Markus Niklasson et al. JOURNAL OF BIOMOLECULAR NMR
- New Views of Functionally Dynamic Proteins by Solution NMR Spectroscopy
- (2016) Lewis E. Kay JOURNAL OF MOLECULAR BIOLOGY
- Evolution of a Protein Interaction Domain Family by Tuning Conformational Flexibility
- (2016) Dustin S. Whitney et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Conformational footprints
- (2016) Buyong Ma et al. Nature Chemical Biology
- The role of protein dynamics in the evolution of new enzyme function
- (2016) Eleanor Campbell et al. Nature Chemical Biology
- Discovery of a regioselectivity switch in nitrating P450s guided by molecular dynamics simulations and Markov models
- (2016) Sheel C. Dodani et al. Nature Chemistry
- Enzyme Dynamics from NMR Spectroscopy
- (2015) Arthur G. Palmer ACCOUNTS OF CHEMICAL RESEARCH
- Markov State Models Provide Insights into Dynamic Modulation of Protein Function
- (2015) Diwakar Shukla et al. ACCOUNTS OF CHEMICAL RESEARCH
- A Structural Ensemble for the Enzyme Cyclophilin Reveals an Orchestrated Mode of Action at Atomic Resolution
- (2015) Celestine N. Chi et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The nature of chemical innovation: new enzymes by evolution
- (2015) Frances H. Arnold QUARTERLY REVIEWS OF BIOPHYSICS
- Systematic Mapping of Protein Mutational Space by Prolonged Drift Reveals the Deleterious Effects of Seemingly Neutral Mutations
- (2015) Liat Rockah-Shmuel et al. PLoS Computational Biology
- Exposing Hidden Alternative Backbone Conformations in X-ray Crystallography Using qFit
- (2015) Daniel A. Keedy et al. PLoS Computational Biology
- Thermal fluctuations of immature SOD1 lead to separate folding and misfolding pathways
- (2015) Ashok Sekhar et al. eLife
- Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography
- (2015) Daniel A Keedy et al. eLife
- NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy
- (2014) Woonghee Lee et al. BIOINFORMATICS
- Evolutionary Aspects of Enzyme Dynamics
- (2014) Judith P. Klinman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Conformational Changes and Free Energies in a Proline Isomerase
- (2014) Elena Papaleo et al. Journal of Chemical Theory and Computation
- Cyclophilin A catalyzes proline isomerization by an electrostatic handle mechanism
- (2014) C. Camilloni et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINT: a software for integration of peak volumes and extraction of relaxation rates
- (2013) Alexandra Ahlner et al. JOURNAL OF BIOMOLECULAR NMR
- Precision is essential for efficient catalysis in an evolved Kemp eliminase
- (2013) Rebecca Blomberg et al. NATURE
- Automated identification of functional dynamic contact networks from X-ray crystallography
- (2013) Henry van den Bedem et al. NATURE METHODS
- Evolutionary biochemistry: revealing the historical and physical causes of protein properties
- (2013) Michael J. Harms et al. NATURE REVIEWS GENETICS
- Towards automated crystallographic structure refinement withphenix.refine
- (2012) Pavel V. Afonine et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Studying “Invisible” Excited Protein States in Slow Exchange with a Major State Conformation
- (2012) Pramodh Vallurupalli et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structure and dynamics of a primordial catalytic fold generated by in vitro evolution
- (2012) Fa-An Chao et al. Nature Chemical Biology
- Linking Crystallographic Model and Data Quality
- (2012) P. A. Karplus et al. SCIENCE
- Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme
- (2012) Nobuhiko Tokuriki et al. Nature Communications
- Modelling dynamics in protein crystal structures by ensemble refinement
- (2012) B Tom Burnley et al. eLife
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Role of Prolylcis/transIsomers in Cyclophilin-AssistedPseudomonas syringaeAvrRpt2 Protease Activation
- (2010) Tobias Aumüller et al. BIOCHEMISTRY
- Hidden alternative structures of proline isomerase essential for catalysis
- (2009) James S. Fraser et al. NATURE
- A 21st century revisionist's view at a turning point in enzymology
- (2009) Zachary D Nagel et al. Nature Chemical Biology
- Exploring protein fitness landscapes by directed evolution
- (2009) Philip A. Romero et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Protein Dynamism and Evolvability
- (2009) N. Tokuriki et al. SCIENCE
- Sending Signals Dynamically
- (2009) R. G. Smock et al. SCIENCE
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