Efficient molecular evolution to generate enantioselective enzymes using a dual-channel microfluidic droplet screening platform
出版年份 2018 全文链接
标题
Efficient molecular evolution to generate enantioselective enzymes using a dual-channel microfluidic droplet screening platform
作者
关键词
-
出版物
Nature Communications
Volume 9, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-03-06
DOI
10.1038/s41467-018-03492-6
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ultrahigh-Throughput Improvement and Discovery of Enzymes Using Droplet-Based Microfluidic Screening
- (2017) Alexis Autour et al. Micromachines
- In Vitro and In Vivo Enzyme Activity Screening via RNA-Based Fluorescent Biosensors for S-Adenosyl-l-homocysteine (SAH)
- (2016) Yichi Su et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Efficient laboratory evolution of computationally designed enzymes with low starting activities using fluorescence-activated droplet sorting
- (2016) Richard Obexer et al. PROTEIN ENGINEERING DESIGN & SELECTION
- A general strategy for expanding polymerase function by droplet microfluidics
- (2016) Andrew C. Larsen et al. Nature Communications
- Transcription factor-based biosensors in biotechnology: current state and future prospects
- (2015) Regina Mahr et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Droplet-based microfluidics for high-throughput screening of a metagenomic library for isolation of microbial enzymes
- (2015) Masahito Hosokawa et al. BIOSENSORS & BIOELECTRONICS
- Improving and repurposing biocatalysts via directed evolution
- (2015) Carl A Denard et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast
- (2015) Mingtao Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Using droplet-based microfluidics to improve the catalytic properties of RNA under multiple-turnover conditions
- (2015) Michael Ryckelynck et al. RNA
- Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics
- (2015) Pierre-Yves Colin et al. Nature Communications
- One in a Million: Flow Cytometric Sorting of Single Cell-Lysate Assays in Monodisperse Picolitre Double Emulsion Droplets for Directed Evolution
- (2014) Anastasia Zinchenko et al. ANALYTICAL CHEMISTRY
- Droplet-Based Microfluidics Platform for Ultra-High-Throughput Bioprospecting of Cellulolytic Microorganisms
- (2014) Majdi Najah et al. CHEMISTRY & BIOLOGY
- High Throughput Screening and Selection Methods for Directed Enzyme Evolution
- (2014) Han Xiao et al. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
- Directed evolution of stereoselective enzymes based on genetic selection as opposed to screening systems
- (2014) Carlos G. Acevedo-Rocha et al. JOURNAL OF BIOTECHNOLOGY
- Evolution of enzyme catalysts caged in biomimetic gel-shell beads
- (2014) Martin Fischlechner et al. Nature Chemistry
- An Improved Single Cell Ultrahigh Throughput Screening Method Based on In Vitro Compartmentalization
- (2014) Fuqiang Ma et al. PLoS One
- Development of a highly sensitive, high-throughput assay for glycosyltransferases using enzyme-coupled fluorescence detection
- (2013) Kazuo Kumagai et al. ANALYTICAL BIOCHEMISTRY
- Double strand DNA-templated copper nanoparticle as a novel fluorescence indicator for label-free detection of polynucleotide kinase activity
- (2013) Liangliang Zhang et al. BIOSENSORS & BIOELECTRONICS
- Laboratory Evolution of Enantiocomplementary Candida antarctica Lipase B Mutants with Broad Substrate Scope
- (2013) Qi Wu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- High-throughput screening for industrial enzyme production hosts by droplet microfluidics
- (2013) Staffan L. Sjostrom et al. LAB ON A CHIP
- Picoliter Cell Lysate Assays in Microfluidic Droplet Compartments for Directed Enzyme Evolution
- (2012) Balint Kintses et al. CHEMISTRY & BIOLOGY
- Combinatorial reshaping of the Candida antarctica lipase A substrate pocket for enantioselectivity using an extremely condensed library
- (2011) A. G. Sandstrom et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fluorescence Activated Cell Sorting as a General Ultra-High-Throughput Screening Method for Directed Evolution of Glycosyltransferases
- (2010) Guangyu Yang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Ultrahigh-throughput screening in drop-based microfluidics for directed evolution
- (2010) J. J. Agresti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
- (2009) Garrett M. Morris et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Directed Evolution of Enantioselective Enzymes: An Unconventional Approach to Asymmetric Catalysis in Organic Chemistry
- (2009) Manfred T. Reetz JOURNAL OF ORGANIC CHEMISTRY
- Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity
- (2009) Jean-Christophe Baret et al. LAB ON A CHIP
- Enzyme engineering for enantioselectivity: from trial-and-error to rational design?
- (2009) Linda G. Otten et al. TRENDS IN BIOTECHNOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started