Single-cell transcriptomics reveal the dynamic of haematopoietic stem cell production in the aorta

Proinflammatory Signals as Fuel for the Fire of Hematopoietic Stem Cell Emergence

(2018) Raquel Espin-Palazon et al.   TRENDS IN CELL BIOLOGY

Conversion of adult endothelium to immunocompetent haematopoietic stem cells

(2017) Raphael Lis et al.   NATURE

Haematopoietic stem and progenitor cells from human pluripotent stem cells

(2017) Ryohichi Sugimura et al.   NATURE

Understanding Hematopoietic Stem Cell Development through Functional Correlation of Their Proliferative Status with the Intra-aortic Cluster Architecture

(2017) Antoniana Batsivari et al.   Stem Cell Reports

Isolation and characterization of circulating tumor cells using a novel workflow combining the CellSearch®system and the CellCelector™

(2016) Martin Horst Dieter Neumann et al.   BIOTECHNOLOGY PROGRESS

De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data

(2016) Dominic Grün et al.   Cell Stem Cell

Concealed expansion of immature precursors underpins acute burst of adult HSC activity in foetal liver

(2016) Stanislav Rybtsov et al.   DEVELOPMENT

Hematopoietic Reprogramming In Vitro Informs In Vivo Identification of Hemogenic Precursors to Definitive Hematopoietic Stem Cells

(2016) Carlos-Filipe Pereira et al.   DEVELOPMENTAL CELL

Tracing haematopoietic stem cell formation at single-cell resolution

(2016) Fan Zhou et al.   NATURE

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells

(2016) Céline Souilhol et al.   Nature Communications

FANTOM5 transcriptome catalog of cellular states based on Semantic MediaWiki

(2016) Imad Abugessaisa et al.   Database-The Journal of Biological Databases and Curation

A Single-Cell Transcriptome Atlas of the Human Pancreas

(2016) Mauro J. Muraro et al.   Cell Systems

Index sorting resolves heterogeneous murine hematopoietic stem cell populations

(2015) Reiner Schulte et al.   EXPERIMENTAL HEMATOLOGY

C-Myb+ Erythro-Myeloid Progenitor-Derived Fetal Monocytes Give Rise to Adult Tissue-Resident Macrophages

(2015) Guillaume Hoeffel et al.   IMMUNITY

The Technology and Biology of Single-Cell RNA Sequencing

(2015) Aleksandra A. Kolodziejczyk et al.   MOLECULAR CELL

Advances and Applications of Single-Cell Sequencing Technologies

(2015) Yong Wang et al.   MOLECULAR CELL

Single-cell messenger RNA sequencing reveals rare intestinal cell types

(2015) Dominic Grün et al.   NATURE

GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1

(2015) Roshana Thambyrajah et al.   NATURE CELL BIOLOGY

Distinct Sources of Hematopoietic Progenitors Emerge before HSCs and Provide Functional Blood Cells in the Mammalian Embryo

(2015) Kathleen E. McGrath et al.   Cell Reports

In Vivo Repopulating Activity Emerges at the Onset of Hematopoietic Specification during Embryonic Stem Cell Differentiation

(2015) Stella Pearson et al.   Stem Cell Reports

Progressive maturation toward hematopoietic stem cells in the mouse embryo aorta

(2014) J.-C. Boisset et al.   BLOOD

Reconstruction of the Mouse Otocyst and Early Neuroblast Lineage at Single-Cell Resolution

(2014) Robert Durruthy-Durruthy et al.   CELL

A Systems Biology Approach for Defining the Molecular Framework of the Hematopoietic Stem Cell Niche

(2014) Pierre Charbord et al.   Cell Stem Cell

Whole-transcriptome analysis of endothelial to hematopoietic stem cell transition reveals a requirement for Gpr56 in HSC generation

(2014) Parham Solaimani Kartalaei et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

(2014) Elisa Gomez Perdiguero et al.   NATURE

Reprogramming human endothelial cells to haematopoietic cells requires vascular induction

(2014) Vladislav M. Sandler et al.   NATURE

Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq

(2014) Barbara Treutlein et al.   NATURE

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

(2014) D. A. Jaitin et al.   SCIENCE

Direct Reprogramming of Murine Fibroblasts to Hematopoietic Progenitor Cells

(2014) Kiran Batta et al.   Cell Reports

Tracing the Origin of the HSC Hierarchy Reveals an SCF-Dependent, IL-3-Independent CD43− Embryonic Precursor

(2014) Stanislav Rybtsov et al.   Stem Cell Reports

Sox17 is indispensable for acquisition and maintenance of arterial identity

(2013) Monica Corada et al.   Nature Communications

Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level

(2013) Gemma Swiers et al.   Nature Communications

Automated selection and harvesting of pluripotent stem cell colonies

(2012) Simone Haupt et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment

(2012) C. Lancrin et al.   BLOOD

Endoglin expression level discriminates long-term hematopoietic from short-term clonogenic progenitor cells in the aorta

(2012) M. Roques et al.   HAEMATOLOGICA

CEL-Seq: Single-Cell RNA-Seq by Multiplexed Linear Amplification

(2012) Tamar Hashimshony et al.   Cell Reports

CD41 is developmentally regulated and differentially expressed on mouse hematopoietic stem cells

(2011) C. Robin et al.   BLOOD

Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region

(2011) Stanislav Rybtsov et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ex vivo time-lapse confocal imaging of the mouse embryo aorta

(2011) Jean-Charles Boisset et al.   Nature Protocols

Hey2 acts upstream of Notch in hematopoietic stem cell specification in zebrafish embryos

(2010) J. M. Rowlinson et al.   BLOOD

Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos

(2010) T. Yokomizo et al.   DEVELOPMENT

In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium

(2010) Jean-Charles Boisset et al.   NATURE

Blood stem cells emerge from aortic endothelium by a novel type of cell transition

(2010) Karima Kissa et al.   NATURE

Haematopoietic stem cells derive directly from aortic endothelium during development

(2010) Julien Y. Bertrand et al.   NATURE

Identification of novel regulators of hematopoietic stem cell development through refinement of stem cell localization and expression profiling

(2009) M. I. Mascarenhas et al.   BLOOD

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

(2009) Michael J. Chen et al.   NATURE

Continuous single-cell imaging of blood generation from haemogenic endothelium

(2009) Hanna M. Eilken et al.   NATURE

The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage

(2009) Christophe Lancrin et al.   NATURE

Extensive Hematopoietic Stem Cell Generation in the AGM Region via Maturation of VE-Cadherin+CD45+ Pre-Definitive HSCs

(2008) Samir Taoudi et al.   Cell Stem Cell

Fate Tracing Reveals the Endothelial Origin of Hematopoietic Stem Cells

(2008) Ann C. Zovein et al.   Cell Stem Cell

All primitive and definitive hematopoietic progenitor cells emerging before E10 in the mouse embryo are products of the yolk sac

(2007) C. T. Lux et al.   BLOOD