Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms
出版年份 2018 全文链接
标题
Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms
作者
关键词
-
出版物
Nature Communications
Volume 9, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-02-08
DOI
10.1038/s41467-018-03045-x
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators
- (2017) Nian Liu et al. NATURE
- Hyperactivation of HUSH complex function by Charcot–Marie–Tooth disease mutation in MORC2
- (2017) Iva A Tchasovnikarova et al. NATURE GENETICS
- De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development
- (2017) Christopher T Gordon et al. NATURE GENETICS
- SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome
- (2017) Natalie D Shaw et al. NATURE GENETICS
- MORC2mutations cause axonal Charcot-Marie-Tooth disease with pyramidal signs
- (2016) Obaid M. Albulym et al. ANNALS OF NEUROLOGY
- The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domain
- (2016) K. Chen et al. BIOCHEMICAL JOURNAL
- Severe axonal Charcot-Marie-Tooth disease with proximal weakness caused byde novomutation in theMORC2gene
- (2016) Petra Laššuthová et al. BRAIN
- MORC2 mutation causes severe spinal muscular atrophy-phenotype, cerebellar atrophy, and diaphragmatic paralysis
- (2016) Gudrun Schottmann et al. BRAIN
- Clinico-genetics in Korean Charcot-Marie-Tooth disease type 2Z withMORC2mutations
- (2016) Young Se Hyun et al. BRAIN
- MORC2mutations in a cohort of Chinese patients with Charcot–Marie–Tooth disease type 2
- (2016) Xin Zhao et al. BRAIN
- Family-wide Characterization of Histone Binding Abilities of Human CW Domain-containing Proteins
- (2016) Yanli Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin
- (2016) Sisi Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase
- (2016) Forest H. Andrews et al. Cell Reports
- Mutations in theMORC2gene cause axonal Charcot–Marie–Tooth disease
- (2015) Teresa Sevilla et al. BRAIN
- Independent Mechanisms Target SMCHD1 to Trimethylated Histone H3 Lysine 9-Modified Chromatin and the Inactive X Chromosome
- (2015) Nicholas J. Brideau et al. MOLECULAR AND CELLULAR BIOLOGY
- Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation
- (2015) Kelan Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells
- (2015) I. A. Tchasovnikarova et al. SCIENCE
- Low-resolution refinement in the programREFMAC
- (2015) G. N. Murshudov ACTA CRYSTALLOGRAPHICA SECTION A
- MORC1 represses transposable elements in the mouse male germline
- (2014) William A. Pastor et al. Nature Communications
- HDAC4 Governs a Transcriptional Program Essential for Synaptic Plasticity and Memory
- (2012) Richard Sando et al. CELL
- Involvement of a GHKL ATPase in RNA-Directed DNA Methylation in Arabidopsis thaliana
- (2012) Zdravko J. Lorković et al. CURRENT BIOLOGY
- Histone deacetylase inhibition suppresses myogenin-dependent atrogene activation in spinal muscular atrophy mice
- (2012) Katherine V. Bricceno et al. HUMAN MOLECULAR GENETICS
- MORC Family ATPases Required for Heterochromatin Condensation and Gene Silencing
- (2012) G. Moissiard et al. SCIENCE
- MORC2 Signaling Integrates Phosphorylation-Dependent, ATPase-Coupled Chromatin Remodeling during the DNA Damage Response
- (2012) Da-Qiang Li et al. Cell Reports
- CaSeO4·0.625H2O – water channel occupation in a bassanite related structure
- (2011) Susanne Fritz et al. ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE
- Prediction of Hydrodynamic and Other Solution Properties of Rigid Proteins from Atomic- and Residue-Level Models
- (2011) A. Ortega et al. BIOPHYSICAL JOURNAL
- Two-step colocalization of MORC3 with PML nuclear bodies
- (2010) Y. Mimura et al. JOURNAL OF CELL SCIENCE
- Involvement of histone deacetylation in MORC2-mediated down-regulation of carbonic anhydrase IX
- (2010) Yangguang Shao et al. NUCLEIC ACIDS RESEARCH
- The MORPHEUS protein crystallization screen
- (2009) Fabrice Gorrec JOURNAL OF APPLIED CRYSTALLOGRAPHY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now