A potential strategy for treating atherosclerosis: improving endothelial function via AMP-activated protein kinase

Macrophage metabolism in atherosclerosis

(2017) Gael F. P. Bories et al.   FEBS LETTERS

Adiponectin, a Therapeutic Target for Obesity, Diabetes, and Endothelial Dysfunction

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Drp1-Dependent Mitochondrial Fission Plays Critical Roles in Physiological and Pathological Progresses in Mammals

(2017) Chenxia Hu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tryptophan depletion under conditions that imitate insulin resistance enhances fatty acid oxidation and induces endothelial dysfunction through reactive oxygen species-dependent and independent pathways

(2017) Theodoros Eleftheriadis et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

A Chemogenomic Screen Reveals Novel Snf1p/AMPK Independent Regulators of Acetyl-CoA Carboxylase

(2017) Bruno L. Bozaquel-Morais et al.   PLoS One

AMPK/α-Ketoglutarate Axis Dynamically Mediates DNA Demethylation in the Prdm16 Promoter and Brown Adipogenesis

(2016) Qiyuan Yang et al.   Cell Metabolism

Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function

(2016) Emilio P. Mottillo et al.   Cell Metabolism

Resveratrol attenuates lipopolysaccharide-induced dysfunction of blood-brain barrier in endothelial cells via AMPK activation

(2016) Min Hu et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling

(2016) C. Rutherford et al.   Science Signaling

AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs

(2016) D. Grahame Hardie et al.   TRENDS IN CELL BIOLOGY

AMP-activated protein kinase attenuates oxLDL uptake in macrophages through PP2A/NF-κB/LOX-1 pathway

(2016) Bo Chen et al.   VASCULAR PHARMACOLOGY

Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling

(2016) C. Rutherford et al.   Science Signaling

Mitochondria-targeted esculetin alleviates mitochondrial dysfunction by AMPK-mediated nitric oxide and SIRT3 regulation in endothelial cells: potential implications in atherosclerosis

(2016) Santosh Karnewar et al.   Scientific Reports

Uncoupling AMPK from autophagy: a foe that hinders the beneficial effects of metformin treatment on metabolic syndrome-associated atherosclerosis? Focus on “Glucose and palmitate uncouple AMPK from autophagy in human aortic endothelial cells”

(2015) Wen-Xing Ding   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Redox Regulation of NLRP3 Inflammasomes: ROS as Trigger or Effector?

(2015) Justine M. Abais et al.   ANTIOXIDANTS & REDOX SIGNALING

Molecular Strategies for Targeting Antioxidants to Mitochondria: Therapeutic Implications

(2015) Nadezda Apostolova et al.   ANTIOXIDANTS & REDOX SIGNALING

Resveratrol inhibits inflammation and ameliorates insulin resistant endothelial dysfunction via regulation of AMP-activated protein kinase and sirtuin 1 activities

(2015) Zifeng Liu et al.   Journal of Diabetes

Inflammation and Cardiovascular Disease: From Pathogenesis to Therapeutic Target

(2014) Enrica Golia et al.   Current Atherosclerosis Reports

AMP-activated protein kinase: a key regulator of energy balance with many roles in human disease

(2014) D. Grahame Hardie   JOURNAL OF INTERNAL MEDICINE

Endothelial dysfunction — A major mediator of diabetic vascular disease

(2013) Cristina M. Sena et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1

(2013) D. N. Tripathi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis

(2012) L. Ouyang et al.   CELL PROLIFERATION

Monocyte Chemoattractant Protein 1 (MCP-1) in obesity and diabetes

(2012) Jun Panee   CYTOKINE

Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation

(2012) Ian P Salt et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Immunometabolism of AMPK in insulin resistance and atherosclerosis

(2012) Morgan D. Fullerton et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Oxidized LDL, LOX-1 and Atherosclerosis

(2011) Sona Mitra et al.   CARDIOVASCULAR DRUGS AND THERAPY

Endothelial cells and magnesium: implications in atherosclerosis

(2011) Jeanette A. M. Maier   CLINICAL SCIENCE

Coenzyme Q10 suppresses oxLDL-induced endothelial oxidative injuries by the modulation of LOX-1-mediated ROS generation via the AMPK/PKC/NADPH oxidase signaling pathway

(2011) Kun-Ling Tsai et al.   MOLECULAR NUTRITION & FOOD RESEARCH

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

2-Deoxy-D-Glucose Treatment of Endothelial Cells Induces Autophagy by Reactive Oxygen Species-Mediated Activation of the AMP-Activated Protein Kinase

(2011) Qilong Wang et al.   PLoS One

Molecular imaging in atherosclerosis

(2010) Andor W. J. M. Glaudemans et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Adenosine Monophosphate-activated Protein Kinase Induces Cholesterol Efflux from Macrophage-derived Foam Cells and Alleviates Atherosclerosis in Apolipoprotein E-deficient Mice

(2010) Dan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The endothelial cell tube formation assay on basement membrane turns 20: state of the science and the art

(2009) Irina Arnaoutova et al.   ANGIOGENESIS

Inflammatory cytokines in vascular dysfunction and vascular disease

(2009) Alexander H. Sprague et al.   BIOCHEMICAL PHARMACOLOGY

Activation of the AMPK-FOXO3 Pathway Reduces Fatty Acid-Induced Increase in Intracellular Reactive Oxygen Species by Upregulating Thioredoxin

(2009) X.-N. Li et al.   DIABETES

The NF- B Family of Transcription Factors and Its Regulation

(2009) A. Oeckinghaus et al.   Cold Spring Harbor Perspectives in Biology

AMP-Activated Protein Kinase Activation by 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) Inhibits Palmitate-Induced Endothelial Cell Apoptosis Through Reactive Oxygen Species Suppression

(2008) Ji-Eun Kim et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES