2-Deoxy-D-Glucose Treatment of Endothelial Cells Induces Autophagy by Reactive Oxygen Species-Mediated Activation of the AMP-Activated Protein Kinase

AMPK in cardiovascular health and disease

(2010) Najeeb A Shirwany et al.   ACTA PHARMACOLOGICA SINICA

Oxidative Stress and Autophagy in Cardiac Disease, Neurological Disorders, Aging and Cancer

(2010) Eric E. Essick et al.   Oxidative Medicine and Cellular Longevity

Autophagy, Redox Signaling, and Ventricular Remodeling

(2009) Narasimman Gurusamy et al.   ANTIOXIDANTS & REDOX SIGNALING

Alzheimer Disease–Associated Peptide, Amyloid β40, Inhibits Vascular Regeneration With Induction of Endothelial Autophagy

(2009) Shin-ichiro Hayashi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Hypoxia-induced downregulation of autophagy mediator Beclin-1 reduces the susceptibility of malignant intestinal epithelial cells to hypoxia-dependent apoptosis

(2009) Byong Hoon Yoo et al.   Autophagy

Autophagy induced by 2-deoxy-D-glucose suppresses intracellular multiplication ofLegionella pneumophilain A/J mouse macrophages

(2009) Fumiko Matsuda et al.   Autophagy

AMPKα1 regulates the antioxidant status of vascular endothelial cells

(2009) Sergio L. Colombo et al.   BIOCHEMICAL JOURNAL

Therapeutics by Cytotoxic Metabolite Accumulation: Pemetrexed Causes ZMP Accumulation, AMPK Activation, and Mammalian Target of Rapamycin Inhibition

(2009) Alexandra C. Racanelli et al.   CANCER RESEARCH

Superoxide is the major reactive oxygen species regulating autophagy

(2009) Y Chen et al.   CELL DEATH AND DIFFERENTIATION

Molecular Insights and Therapeutic Targets for Diabetic Endothelial Dysfunction

(2009) Jian Xu et al.   CIRCULATION

Autophagy in Ischemic Heart Disease

(2009) Åsa B. Gustafsson et al.   CIRCULATION RESEARCH

Activation and Signaling by the AMP-Activated Protein Kinase in Endothelial Cells

(2009) Beate Fisslthaler et al.   CIRCULATION RESEARCH

Oxidized Metabolites of Oltipraz Exert Cytoprotective Effects against Arachidonic Acid through AMP-Activated Protein Kinase-Dependent Cellular Antioxidant Effect and Mitochondrial Protection

(2009) Y. N. Kwon et al.   DRUG METABOLISM AND DISPOSITION

FoxO Transcription Factors Promote Autophagy in Cardiomyocytes

(2009) Arunima Sengupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Simian Virus 40 Small T Antigen Activates AMPK and Triggers Autophagy To Protect Cancer Cells from Nutrient Deprivation

(2009) S. H. Kumar et al.   JOURNAL OF VIROLOGY

 1-AMP-Activated Protein Kinase Regulates Hypoxia-Induced Na,K-ATPase Endocytosis via Direct Phosphorylation of Protein Kinase C 

(2009) G. A. Gusarova et al.   MOLECULAR AND CELLULAR BIOLOGY

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

Increased levels of superoxide and H2O2mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation

(2008) Nùkhet Aykin-Burns et al.   BIOCHEMICAL JOURNAL

The role of autophagy in the heart

(2008) K Nishida et al.   CELL DEATH AND DIFFERENTIATION

AMP-ACTIVATED PROTEIN KINASE ACTIVATION AS A STRATEGY FOR PROTECTING VASCULAR ENDOTHELIAL FUNCTION

(2008) Ming-Hui Zou et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Autophagy in atherosclerosis

(2008) Wim Martinet et al.   Current Atherosclerosis Reports

Upregulation of Mitochondrial Uncoupling Protein-2 by the AMP-Activated Protein Kinase in Endothelial Cells Attenuates Oxidative Stress in Diabetes

(2008) Z. Xie et al.   DIABETES

Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS

(2008) Tatyana A. Klimova et al.   FASEB JOURNAL

High molecular weight adiponectin inhibits proliferation of hepatic stellate cells via activation of adenosine monophosphate-activated protein kinase

(2008) Masayuki Adachi et al.   HEPATOLOGY

Reactive Nitrogen Species Is Required for the Activation of the AMP-activated Protein Kinase by Statinin Vivo

(2008) Hyoung Chul Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of the activities of AMP‐activated protein kinase, protein kinase B, and mammalian target of rapamycin by limiting energy availability with 2‐deoxyglucose

(2008) Weiqin Jiang et al.   MOLECULAR CARCINOGENESIS

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Autophagy is involved in the ischemic preconditioning

(2008) Hee-Kwon Park et al.   NEUROSCIENCE LETTERS

Drug/diet synergy for managing malignant astrocytoma in mice: 2-deoxy-D-glucose and the restricted ketogenic diet

(2008) Jeremy Marsh et al.   Nutrition & Metabolism