In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis

Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2

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Polycomb Repressive Complex 2 Is a Barrier to KRAS-Driven Inflammation and Epithelial-Mesenchymal Transition in Non-Small-Cell Lung Cancer

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The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells

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Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung Cancer

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LKB1 Inactivation Elicits a Redox Imbalance to Modulate Non-small Cell Lung Cancer Plasticity and Therapeutic Response

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A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC

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Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis

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EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors

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The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

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CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

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Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia

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Rapid modelling of cooperating genetic events in cancer through somatic genome editing

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CRISPR-mediated direct mutation of cancer genes in the mouse liver

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Nkx2-1 Represses a Latent Gastric Differentiation Program in Lung Adenocarcinoma

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Genome engineering using the CRISPR-Cas9 system

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Transcriptional regulation by Polycomb group proteins

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Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

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Multiplex Genome Engineering Using CRISPR/Cas Systems

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Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

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Identification of RET gene fusion by exon array analyses in “pan-negative” lung cancer from never smokers

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LKB1-AMPK axis revisited

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AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress

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Comprehensive genomic characterization of squamous cell lung cancers

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Polycomb repressive complex 2 is required for MLL-AF9 leukemia

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UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity

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Fast and accurate long-read alignment with Burrows–Wheeler transform

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The histone demethylase UTX enables RB-dependent cell fate control

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Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

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