Oleuropein Aglycone Protects against MAO-A-Induced Autophagy Impairment and Cardiomyocyte Death through Activation of TFEB

Monoamine Oxidases, Oxidative Stress, and Altered Mitochondrial Dynamics in Cardiac Ageing

(2017) Damien Maggiorani et al.   Oxidative Medicine and Cellular Longevity

Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis

(2017) Ismail Sergin et al.   Nature Communications

Green Tea Polyphenols, Mimicking the Effects of Dietary Restriction, Ameliorate High-Fat Diet-Induced Kidney Injury via Regulating Autophagy Flux

(2017) Xiao Xie et al.   Nutrients

Oxidative Stress by Monoamine Oxidase-A Impairs Transcription Factor EB Activation and Autophagosome Clearance, Leading to Cardiomyocyte Necrosis and Heart Failure

(2016) Yohan Santin et al.   ANTIOXIDANTS & REDOX SIGNALING

Olive polyphenols: new promising agents to combat aging-associated neurodegeneration

(2016) Fiorella Casamenti et al.   Expert Review of Neurotherapeutics

Nutraceutical Properties of Olive Oil Polyphenols. An Itinerary from Cultured Cells through Animal Models to Humans

(2016) Stefania Rigacci et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Polyphenol Oleuropein Aglycone Modulates the PARP1-SIRT1 Interplay: An In Vitro and In Vivo Study

(2016) Ilaria Luccarini et al.   JOURNAL OF ALZHEIMERS DISEASE

Staying young at heart: autophagy and adaptation to cardiac aging

(2016) Leonardo J. Leon et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Oleuropein attenuates the progression of heart failure in rats by antioxidant and antiinflammatory effects

(2016) Zeinab Janahmadi et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Resveratrol Enhances Autophagic Flux and Promotes Ox-LDL Degradation in HUVECs via Upregulation of SIRT1

(2016) Yanlin Zhang et al.   Oxidative Medicine and Cellular Longevity

Monoamine Oxidase Is Overactivated in Left and Right Ventricles from Ischemic Hearts: An Intriguing Therapeutic Target

(2016) Maria Elena Manni et al.   Oxidative Medicine and Cellular Longevity

Curcumin targets the TFEB-lysosome pathway for induction of autophagy

(2016) Jianbin Zhang et al.   Oncotarget

Olive polyphenols: new promising agents to combat aging-associated neurodegeneration

(2016) Fiorella Casamenti et al.   Expert Review of Neurotherapeutics

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

(2015) Diego L. Medina et al.   NATURE CELL BIOLOGY

Oleuropein aglycone induces autophagy via the AMPK/mTOR signalling pathway: a mechanistic insight

(2015) Stefania Rigacci et al.   Oncotarget

Beneficial properties of natural phenols: Highlight on protection against pathological conditions associated with amyloid aggregation

(2014) Massimo Stefani et al.   BIOFACTORS

Exchange protein directly activated by cAMP 1 promotes autophagy during cardiomyocyte hypertrophy

(2014) Anne-Coline Laurent et al.   CARDIOVASCULAR RESEARCH

Resveratrol-enhanced autophagic flux ameliorates myocardial oxidative stress injury in diabetic mice

(2014) Bo Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Oleuropein prevents doxorubicin-induced cardiomyopathy interfering with signaling molecules and cardiomyocyte metabolism

(2014) Ioanna Andreadou et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Monoamine oxidases as sources of oxidants in the heart

(2014) Nina Kaludercic et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Monoamine Oxidase is a Major Determinant of Redox Balance in Human Atrial Myocardium and is Associated With Postoperative Atrial Fibrillation

(2014) Ethan J. Anderson et al.   Journal of the American Heart Association

Why should autophagic flux be assessed?

(2013) Xiao-jie Zhang et al.   ACTA PHARMACOLOGICA SINICA

Autophagy: a potential therapeutic target in lung diseases

(2013) Kiichi Nakahira et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The biotransformation of oleuropein in rats

(2013) Peiyan Lin et al.   BIOMEDICAL CHROMATOGRAPHY

Exposure of cardiomyocytes to angiotensin II induces over-activation of monoamine oxidase type A: Implications in heart failure

(2013) Maria Elena Manni et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Epigallocatechin Gallate (EGCG) Stimulates Autophagy in Vascular Endothelial Cells

(2013) Hae-Suk Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human absorption and metabolism of oleuropein and hydroxytyrosol ingested as olive (Olea europaeaL.) leaf extract

(2013) Martin de Bock et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The Polyphenol Oleuropein Aglycone Protects TgCRND8 Mice against Aß Plaque Pathology

(2013) Cristina Grossi et al.   PLoS One

p53-PGC-1α Pathway Mediates Oxidative Mitochondrial Damage and Cardiomyocyte Necrosis Induced by Monoamine Oxidase-A Upregulation: Role in Chronic Left Ventricular Dysfunction in Mice

(2012) Christelle Villeneuve et al.   ANTIOXIDANTS & REDOX SIGNALING

Autophagy modulation as a potential therapeutic target for diverse diseases

(2012) David C. Rubinsztein et al.   NATURE REVIEWS DRUG DISCOVERY

Distribution of olive oil phenolic compounds in rat tissues after administration of a phenolic extract from olive cake

(2011) Aida Serra et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Exploratory analysis of human urine by LC–ESI-TOF MS after high intake of olive oil: understanding the metabolism of polyphenols

(2010) Rocío García-Villalba et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Nitric Oxide/Reactive Oxygen Species Generation and Nitroso/Redox Imbalance in Heart Failure: From Molecular Mechanisms to Therapeutic Implications

(2010) Chiara Nediani et al.   ANTIOXIDANTS & REDOX SIGNALING

Bioavailability of the Polyphenols: Status and Controversies

(2010) Massimo D’Archivio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial Turnover and Aging of Long-Lived Postmitotic Cells: The Mitochondrial–Lysosomal Axis Theory of Aging

(2009) Alexei Terman et al.   ANTIOXIDANTS & REDOX SIGNALING

Monoamine Oxidase A–Mediated Enhanced Catabolism of Norepinephrine Contributes to Adverse Remodeling and Pump Failure in Hearts With Pressure Overload

(2009) Nina Kaludercic et al.   CIRCULATION RESEARCH

Powerful Protective Role of 3,4-Dihydroxyphenylethanol−Elenolic Acid Dialdehyde against Erythrocyte Oxidative-Induced Hemolysis

(2009) Fátima Paiva-Martins et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Phenolic compounds in olive oil: antioxidant, health and organoleptic activities according to their chemical structure

(2009) M. Servili et al.   INFLAMMOPHARMACOLOGY