Development of oligonucleotide-based antagonists of Ebola virus protein 24 inhibiting its interaction with karyopherin alpha 1

Macrocyclic peptide inhibitors for the protein–protein interaction of Zaire Ebola virus protein 24 and karyopherin alpha 5

(2017) Xiao Song et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Structural basis for IL-1α recognition by a modified DNA aptamer that specifically inhibits IL-1α signaling

(2017) Xiaoming Ren et al.   Nature Communications

Selection, Characterization and Application of Artificial DNA Aptamer Containing Appended Bases with Sub-nanomolar Affinity for a Salivary Biomarker

(2017) Hirotaka Minagawa et al.   Scientific Reports

Post-SELEX optimization of aptamers

(2016) Shunxiang Gao et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Consecutive incorporation of functionalized nucleotides with amphiphilic side chains by novel KOD polymerase mutant

(2016) Hidekazu Hoshino et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Importin α: a key molecule in nuclear transport and non-transport functions

(2016) Yoichi Miyamoto et al.   JOURNAL OF BIOCHEMISTRY

Progression of Ebola Therapeutics During the 2014–2015 Outbreak

(2016) Emelissa J. Mendoza et al.   TRENDS IN MOLECULAR MEDICINE

Functional characterization of importin α8 as a classical nuclear localization signal receptor

(2015) Chihiro Kimoto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Aptamer–Drug Conjugates

(2015) Guizhi Zhu et al.   BIOCONJUGATE CHEMISTRY

ATP1A1-Mediated Src Signaling Inhibits Coronavirus Entry into Host Cells

(2015) Christine Burkard et al.   JOURNAL OF VIROLOGY

A Single Phosphorodiamidate Morpholino Oligomer Targeting VP24 Protects Rhesus Monkeys against Lethal Ebola Virus Infection

(2015) Travis K. Warren et al.   mBio

Rapid evaluation and quality control of next generation sequencing data with FaQCs

(2014) Chien-Chi Lo et al.   BMC BIOINFORMATICS

Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1

(2014) Wei Xu et al.   Cell Host & Microbe

Crystal Structure of Interleukin-6 in Complex with a Modified Nucleic Acid Ligand

(2014) Amy D. Gelinas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elucidation of the Ebola Virus VP24 Cellular Interactome and Disruption of Virus Biology through Targeted Inhibition of Host-Cell Protein Function

(2014) Isabel García-Dorival et al.   JOURNAL OF PROTEOME RESEARCH

Capillary Electrophoresis–Systematic Evolution of Ligands by Exponential Enrichment Selection of Base- and Sugar-Modified DNA Aptamers: Target Binding Dominated by 2′-O,4′-C-Methylene-Bridged/Locked Nucleic Acid Primer

(2013) Yuuya Kasahara et al.   ANALYTICAL CHEMISTRY

Development of RNA Aptamers Targeting Ebola Virus VP35

(2013) Jennifer M. Binning et al.   BIOCHEMISTRY

Efficacy of Base-Modification on Target Binding of Small Molecule DNA Aptamers

(2013) Yuri Imaizumi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets

(2012) D. R. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery

(2011) Larry Gold et al.   PLoS One

Development of DNA aptamers using Cell-SELEX

(2010) Kwame Sefah et al.   Nature Protocols

Aptamers as therapeutics

(2010) Anthony D. Keefe et al.   NATURE REVIEWS DRUG DISCOVERY

The Chemical Biology of Aptamers

(2009) Günter Mayer   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tetherin-mediated restriction of filovirus budding is antagonized by the Ebola glycoprotein

(2009) Rachel L. Kaletsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SELEX with modified nucleotides

(2008) Anthony D Keefe et al.   CURRENT OPINION IN CHEMICAL BIOLOGY