Post-SELEX optimization of aptamers

Gonyautoxin 1/4 aptamers with high-affinity and high-specificity: From efficient selection to aptasensor application

(2016) Shunxiang Gao et al.   BIOSENSORS & BIOELECTRONICS

A saxitoxin-binding aptamer with higher affinity and inhibitory activity optimized by rational site-directed mutagenesis and truncation

(2015) X. Zheng et al.   TOXICON

A Systematic Study of the Features Critical for Designing a High Avidity Multivalent Aptamer

(2015) Xiaoching Zhao et al.   Nucleic Acid Therapeutics

Nucleic Acid Aptamers: New Methods for Selection, Stabilization, and Application in Biomedical Science

(2014) Hoon Young Kong et al.   Biomolecules & Therapeutics

Comparison of the ‘Chemical’ and ‘Structural’ Approaches to the Optimization of the Thrombin-Binding Aptamer

(2014) Olga Tatarinova et al.   PLoS One

Aptamer-modified nanoparticles and their use in cancer diagnostics and treatment

(2014) C Reinemann et al.   SWISS MEDICAL WEEKLY

Probing high-affinity 11-mer DNA aptamer against Lup an 1 (β-conglutin)

(2013) P. Nadal et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Inhibition of human neutrophil activity by an RNA aptamer bound to interleukin-8

(2013) Ho Jin Sung et al.   BIOMATERIALS

Aptamers: Molecules of great potential

(2013) Filip Radom et al.   BIOTECHNOLOGY ADVANCES

Investigating the Antiproliferative Activity of High Affinity DNA Aptamer on Cancer Cells

(2013) Harleen Kaur et al.   PLoS One

Aptamers as Theranostic Agents: Modifications, Serum Stability and Functionalisation

(2013) Sarah Shigdar et al.   SENSORS

Affinity Improvement of a VEGF Aptamer by in Silico Maturation for a Sensitive VEGF-Detection System

(2012) Yoshihiko Nonaka et al.   ANALYTICAL CHEMISTRY

Properties of an ‘LNA’-modified ricin RNA aptamer

(2012) Charlotte Förster et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

G-Quadruplex and i-Motif Are Mutually Exclusive in ILPR Double-Stranded DNA

(2012) Soma Dhakal et al.   BIOPHYSICAL JOURNAL

Polyvalent nucleic acid aptamers and modulation of their activity: a focus on the thrombin binding aptamer

(2012) Domenica Musumeci et al.   PHARMACOLOGY & THERAPEUTICS

Aptamers Against Cell Surface Receptors: Selection, Modification and Application

(2011) J. Wang et al.   CURRENT MEDICINAL CHEMISTRY

Improving the Stability of Aptamers by Chemical Modification

(2011) R. E. Wang et al.   CURRENT MEDICINAL CHEMISTRY

Antisense drug discovery and development

(2011) Tsuyoshi Yamamoto et al.   Future Medicinal Chemistry

Aptamer-Conjugated Nanoparticles Efficiently Control the Activity of Thrombin

(2010) Yen-Chun Shiang et al.   ADVANCED FUNCTIONAL MATERIALS

Engineering Dendritic Aptamer Assemblies as Superior Inhibitors of Protein Function

(2010) Youngmi Kim et al.   Chemistry-An Asian Journal

Protection of HIV Neutralizing Aptamers against Rectal and Vaginal Nucleases

(2010) Michael D. Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bioimaging of Nucleolin Aptamer-Containing 5-(N-benzylcarboxyamide)-2′-deoxyuridine More Capable of Specific Binding to Targets in Cancer Cells

(2010) Kyue Yim Lee et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Enhanced anti-HIV-1 activity of G-quadruplexes comprising locked nucleic acids and intercalating nucleic acids

(2010) Erik B. Pedersen et al.   NUCLEIC ACIDS RESEARCH

Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer

(2010) Anna Pasternak et al.   NUCLEIC ACIDS RESEARCH

A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia

(2010) Prabodhika R. Mallikaratchy et al.   NUCLEIC ACIDS RESEARCH

Sequence and Structural Features of RNA Aptamer Against Myasthenic Autoantibodies

(2009) Jung-Sun Cho et al.   OLIGONUCLEOTIDES

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection

(2009) R. E. Lanford et al.   SCIENCE

Bioinformatic Analysis of the Contribution of Primer Sequences to Aptamer Structures

(2008) Matthew C. Cowperthwaite et al.   JOURNAL OF MOLECULAR EVOLUTION

Anticoagulant characteristics of HD1-22, a bivalent aptamer that specifically inhibits thrombin and prothrombinase

(2008) J. MÜLLER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE

Molecular assembly for high-performance bivalent nucleic acid inhibitor

(2008) Y. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA