A novel mouse model for ataxia-telangiectasia with a N-terminal mutation displays a behavioral defect and a low incidence of lymphoma but no increased oxidative burden

NADPH oxidase 4 is a critical mediator in Ataxia telangiectasia disease

(2015) Urbain Weyemi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Strain Background Determines Lymphoma Incidence in Atm Knockout Mice

(2015) Paula C. Genik et al.   NEOPLASIA

ATM-Dependent Phosphorylation of MEF2D Promotes Neuronal Survival after DNA Damage

(2014) S. F. Chan et al.   JOURNAL OF NEUROSCIENCE

The Interaction of the Atm Genotype with Inflammation and Oxidative Stress

(2014) Yan Yang et al.   PLoS One

Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency

(2014) L Carlessi et al.   Cell Death & Disease

The appropriateness of the mouse model for ataxia-telangiectasia: Neurological defects but no neurodegeneration

(2013) Martin F. Lavin   DNA REPAIR

Concurrent V(D)J recombination and DNA end instability increase interchromosomal trans -rearrangements in ATM-deficient thymocytes

(2013) Steven Bowen et al.   NUCLEIC ACIDS RESEARCH

ATM signalling and cancer

(2013) C A Cremona et al.   ONCOGENE

ATM Influences the Efficiency of TCRβ Rearrangement, Subsequent TCRβ-Dependent T Cell Development, and Generation of the Pre-Selection TCRβ CDR3 Repertoire

(2013) Karen S. Hathcock et al.   PLoS One

Mitochondria and Cancer: Past, Present, and Future

(2013) M. L. Verschoor et al.   Biomed Research International

Process for immune defect and chromosomal translocation during early thymocyte development lacking ATM

(2012) T. Isoda et al.   BLOOD

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice

(2012) Kenta Yamamoto et al.   JOURNAL OF CELL BIOLOGY

Loss of ATM kinase activity leads to embryonic lethality in mice

(2012) Jeremy A. Daniel et al.   JOURNAL OF CELL BIOLOGY

P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferation

(2012) Ping Li et al.   MOLECULAR BIOLOGY OF THE CELL

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

ATM and the Molecular Pathogenesis of Ataxia Telangiectasia

(2011) Peter J. McKinnon   Annual Review of Pathology-Mechanisms of Disease

Mitochondrial dysfunction in ataxia-telangiectasia

(2011) Y. A. Valentin-Vega et al.   BLOOD

ATM protects against oxidative stress induced by oxidized low-density lipoprotein

(2011) Michaela Semlitsch et al.   DNA REPAIR

Presence of ATM protein and residual kinase activity correlates with the phenotype in ataxia-telangiectasia: A genotype-phenotype study

(2011) Mijke M. M. Verhagen et al.   HUMAN MUTATION

Signal transduction by reactive oxygen species

(2011) Toren Finkel   JOURNAL OF CELL BIOLOGY

Stable Brain ATM Message and Residual Kinase-Active ATM Protein in Ataxia-Telangiectasia

(2011) J. Li et al.   JOURNAL OF NEUROSCIENCE

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

X-linked disorders with cerebellar dysgenesis

(2011) Ginevra Zanni et al.   Orphanet Journal of Rare Diseases

ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair

(2010) Claudia Cosentino et al.   EMBO JOURNAL

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks

(2010) Shan Zha et al.   NATURE

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

(2010) A. Alexander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging common themes in regulation of PIKKs and PI3Ks

(2009) Harri Lempiäinen et al.   EMBO JOURNAL

Essential Role for DNA-PKcs in DNA Double-Strand Break Repair and Apoptosis in ATM-Deficient Lymphocytes

(2009) Elsa Callén et al.   MOLECULAR CELL

Effects of antioxidants on cancer prevention and neuromotor performance in Atm deficient mice

(2007) Ramune Reliene et al.   FOOD AND CHEMICAL TOXICOLOGY