Synthesis of novel 1,2,3-triazole based artemisinin derivatives and their antiproliferative activity

Antiproliferative and antimicrobial efficacy of the compounds isolated from the roots of Oenothera biennis L.

(2017) Shilpi Singh et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Synthesis of a series of novel dihydroartemisinin monomers and dimers containing chalcone as a linker and their anticancer activity

(2016) Rashmi Gaur et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Artemisinin and Its Derivatives as a Repurposing Anticancer Agent: What Else Do We Need to Do?

(2016) Zhe Li et al.   MOLECULES

Triazole analog 1-(1-benzyl-5-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)-2-(4-bromophenylamino)-1-(4-chlorophenyl)ethanol induces reactive oxygen species and autophagy-dependent apoptosis in both in vitro and in vivo breast cancer models

(2015) Hamidullah et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Diastereoselective Synthesis of β-Ether Derivatives of Artemisinin, an Antimalarial Drug: The Effect of Nitrile on Stereoselectivity

(2015) Hemender R. Chand et al.   Asian Journal of Organic Chemistry

Synthesis of cyclic 1,9-acetal derivatives of forskolin and their bioactivity evaluation

(2014) Devendar Ponnam et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel 1H-1,2,3-, 2H-1,2,3-, 1H-1,2,4- and 4H-1,2,4-triazole derivatives: a patent review (2008 – 2011)

(2013) Vitor F Ferreira et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Click Chemistry: 1,2,3-Triazoles as Pharmacophores

(2011) Sandip G. Agalave et al.   Chemistry-An Asian Journal

Artesunate inhibits growth and induces apoptosis in human osteosarcoma HOS cell line in vitro and in vivo

(2011) Qiang Xu et al.   Journal of Zhejiang University-SCIENCE B

Heme as Trigger and Target for Trioxane-Containing Antimalarial Drugs†

(2010) Bernard Meunier et al.   ACCOUNTS OF CHEMICAL RESEARCH

Effect of artemisinin derivatives on apoptosis and cell cycle in prostate cancer cells

(2010) Colm Morrissey et al.   ANTI-CANCER DRUGS

In vitro study of the anti-cancer effects of artemisone alone or in combination with other chemotherapeutic agents

(2010) Andrew M. Gravett et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Dihydroartemisinin inactivates NF-κB and potentiates the anti-tumor effect of gemcitabine on pancreatic cancer both in vitro and in vivo

(2010) Shuang-Jia Wang et al.   CANCER LETTERS

The Role of Heme and the Mitochondrion in the Chemical and Molecular Mechanisms of Mammalian Cell Death Induced by the Artemisinin Antimalarials

(2010) Amy E. Mercer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Artesunate Activates Mitochondrial Apoptosis in Breast Cancer Cells via Iron-catalyzed Lysosomal Reactive Oxygen Species Production

(2010) Anne Hamacher-Brady et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacological significance of triazole scaffold

(2010) Rajeev Kharb et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines

(2009) Martin Michaelis et al.   BIOCHEMICAL PHARMACOLOGY

Artemisinin and its derivatives: a novel class of anti-malarial and anti-cancer agents

(2009) Devdutt Chaturvedi et al.   CHEMICAL SOCIETY REVIEWS

Drug interactions involving the new second- and third-generation antiepileptic drugs

(2009) Cecilie Johannessen Landmark et al.   Expert Review of Neurotherapeutics

Heme Mediates Cytotoxicity from Artemisinin and Serves as a General Anti-Proliferation Target

(2009) Shiming Zhang et al.   PLoS One

Experimental Therapy of Hepatoma with Artemisinin and Its Derivatives: In vitro and In vivo Activity, Chemosensitization, and Mechanisms of Action

(2008) J. Hou et al.   CLINICAL CANCER RESEARCH

Anti-Inflammatory and Analgesic Potency of Carboxyamidotriazole, a Tumorostatic Agent

(2008) L. Guo et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Anticancer properties of artemisinin derivatives and their targeted delivery by transferrin conjugation

(2007) Ikuhiko Nakase et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS