Artemisinin and Its Derivatives as a Repurposing Anticancer Agent: What Else Do We Need to Do?
出版年份 2016 全文链接
标题
Artemisinin and Its Derivatives as a Repurposing Anticancer Agent: What Else Do We Need to Do?
作者
关键词
-
出版物
MOLECULES
Volume 21, Issue 10, Pages 1331
出版商
MDPI AG
发表日期
2016-10-10
DOI
10.3390/molecules21101331
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Efficacy of artemisinin-based combination therapies for the treatment of falciparum malaria in Pakistan (2007–2015): In vivo response and dhfr and dhps mutations
- (2016) Qutbuddin Kakar et al. ACTA TROPICA
- In vitro selection of Plasmodium falciparum Pfcrt and Pfmdr1 variants by artemisinin
- (2016) Muturi J. Njokah et al. MALARIA JOURNAL
- The production and exportation of artemisinin-derived drugs in China: current status and existing challenges
- (2016) Yangmu Huang et al. MALARIA JOURNAL
- Alendronate-Loaded Modified Drug Delivery Lipid Particles Intended for Improved Oral and Topical Administration
- (2016) Lacramioara Ochiuz et al. MOLECULES
- Clinical and non-clinical safety of artemisinin derivatives in pregnancy
- (2016) Caroline Gomes et al. REPRODUCTIVE TOXICOLOGY
- Halofuginone and artemisinin synergistically arrest cancer cells at the G1/G0 phase by upregulating p21Cip1 and p27Kip1
- (2016) Guoqing Chen et al. Oncotarget
- Aspirin and NSAIDs for breast cancer chemoprevention
- (2015) Eugenia Ch Yiannakopoulou EUROPEAN JOURNAL OF CANCER PREVENTION
- Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells
- (2015) Edna Ooko et al. PHYTOMEDICINE
- A Randomised, Double Blind, Placebo-Controlled Pilot Study of Oral Artesunate Therapy for Colorectal Cancer
- (2015) Sanjeev Krishna et al. EBioMedicine
- A Multifunctional Polymeric Nanotheranostic System Delivers Doxorubicin and Imaging Agents across the Blood–Brain Barrier Targeting Brain Metastases of Breast Cancer
- (2014) Jason Li et al. ACS Nano
- Artesunate induces G2/M cell cycle arrest through autophagy induction in breast cancer cells
- (2014) Kai Chen et al. ANTI-CANCER DRUGS
- Enhancing the in vitro anti-cancer efficacy of artesunate by loading into poly-d,l-lactide-co-glycolide (PLGA) nanoparticles
- (2014) Hanh Thuy Nguyen et al. ARCHIVES OF PHARMACAL RESEARCH
- Multifunctional mesoporous nanoparticles as pH-responsive Fe2+ reservoirs and artemisinin vehicles for synergistic inhibition of tumor growth
- (2014) Jian Chen et al. BIOMATERIALS
- Phase 2 study of carfilzomib, thalidomide, and dexamethasone as induction/consolidation therapy for newly diagnosed multiple myeloma
- (2014) P. Sonneveld et al. BLOOD
- Dihydroartemisinin targets VEGFR2 via the NF-κB pathway in endothelial cells to inhibit angiogenesis
- (2014) Fengyun Dong et al. CANCER BIOLOGY & THERAPY
- Unbiased Compound Screening Identifies Unexpected Drug Sensitivities and Novel Treatment Options for Gastrointestinal Stromal Tumors
- (2014) S. Boichuk et al. CANCER RESEARCH
- Aspirin in gastrointestinal oncology
- (2014) Ruth E. Langley et al. CURRENT OPINION IN ONCOLOGY
- Population pharmacokinetics of artesunate and dihydroartemisinin during long-term oral administration of artesunate to patients with metastatic breast cancer
- (2014) Therese Ericsson et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- In vivo pharmacokinetics and biodistribution of resveratrol-loaded solid lipid nanoparticles for brain delivery
- (2014) S. Jose et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Enhanced delivery of artemisinin and its analogues to cancer cells by their adducts with human serum transferrin
- (2014) Yan Yang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Artesunate Induces Cell Death in Human Cancer Cells via Enhancing Lysosomal Function and Lysosomal Degradation of Ferritin
- (2014) Nai-Di Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The activation of c-Jun NH2-terminal kinase is required for dihydroartemisinin-induced autophagy in pancreatic cancer cells
- (2014) Guang Jia et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Direct Binding of Arsenic Trioxide to AMPK and Generation of Inhibitory Effects on Acute Myeloid Leukemia Precursors
- (2014) E. M. Beauchamp et al. MOLECULAR CANCER THERAPEUTICS
- Chronic Thalidomide and Chemoembolization for Hepatocellular Carcinoma
- (2014) J. Wu et al. ONCOLOGIST
- Nanoparticles and the Blood-Brain Barrier: Advancing from In-Vitro Models Towards Therapeutic Significance
- (2014) David J. Mc Carthy et al. PHARMACEUTICAL RESEARCH
- Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK
- (2014) X. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dihydroartemisinin inhibits vascular endothelial growth factor-induced endothelial cell migration by a p38 mitogen-activated protein kinase-independent pathway
- (2014) LING GUO et al. Experimental and Therapeutic Medicine
- Iron Metabolism Regulates p53 Signaling through Direct Heme-p53 Interaction and Modulation of p53 Localization, Stability, and Function
- (2014) Jia Shen et al. Cell Reports
- Preparation, characterization and in vitro efficacy of magnetic nanoliposomes containing the artemisinin and transferrin
- (2014) Amir Gharib et al. DARU-Journal of Pharmaceutical Sciences
- Dihydroartemisinin promotes angiogenesis during the early embryonic development of zebrafish
- (2013) Qian Ba et al. ACTA PHARMACOLOGICA SINICA
- Novel artemisinin derivatives with potential usefulness against liver/colon cancer and viral hepatitis
- (2013) Alba G. Blazquez et al. BIOORGANIC & MEDICINAL CHEMISTRY
- In vivostudy of effects of artesunate nanoliposomes on human hepatocellular carcinoma xenografts in nude mice
- (2013) Meihua Jin et al. DRUG DELIVERY
- Lymphoma and myeloma cells are highly sensitive to growth arrest and apoptosis induced by artesunate
- (2013) Toril Holien et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Synergistic Inhibition of Angiogenesis by Artesunate and CaptoprilIn VitroandIn Vivo
- (2013) Benjamin Krusche et al. Evidence-based Complementary and Alternative Medicine
- Preparation and optimization of transferrin-modified-artemether lipid nanospheres based on the orthogonal design of emulsion formulation and physically electrostatic adsorption
- (2013) S.E. Eltayeb et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Artemisinin rewires the protein interaction network in cancer cells: network analysis, pathway identification, and target prediction
- (2013) Chao Huang et al. Molecular BioSystems
- Artemether Combined with shRNA Interference of Vascular Cell Adhesion Molecule-1 Significantly Inhibited the Malignant Biological Behavior of Human Glioma Cells
- (2013) Ying-Bin Wang et al. PLoS One
- Artesunate induces G0/G1 cell cycle arrest and iron-mediated mitochondrial apoptosis in A431 human epidermoid carcinoma cells
- (2012) Zhongyong Jiang et al. ANTI-CANCER DRUGS
- Development of artemisinin compounds for cancer treatment
- (2012) Henry C. Lai et al. INVESTIGATIONAL NEW DRUGS
- Artesunate induces apoptosis via a Bak-mediated caspase-independent intrinsic pathway in human lung adenocarcinoma cells
- (2012) Chenjuan Zhou et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials
- (2012) Peter M Rothwell et al. LANCET
- Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials
- (2012) Annemijn M Algra et al. LANCET ONCOLOGY
- LyP-1 Modification To Enhance Delivery of Artemisinin or Fluorescent Probe Loaded Polymeric Micelles to Highly Metastatic Tumor and Its Lymphatics
- (2012) Zhaohui Wang et al. MOLECULAR PHARMACEUTICS
- Dihydroartemisinin Exerts Its Anticancer Activity through Depleting Cellular Iron via Transferrin Receptor-1
- (2012) Qian Ba et al. PLoS One
- Correction: Dihydroartemisinin Enhances Apo2L/TRAIL-Mediated Apoptosis in Pancreatic Cancer Cells via ROS-Mediated Up-Regulation of Death Receptor 5
- (2012) Rui Kong et al. PLoS One
- An injectable hybrid nanoparticle-in-oil-in-water submicron emulsion for improved delivery of poorly soluble drugs
- (2012) Shuo Wang et al. Nanoscale Research Letters
- Dihydroartemisinin inhibits angiogenesis in pancreatic cancer by targeting the NF-κB pathway
- (2011) Shuang-Jia Wang et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Artesunate enhances radiosensitivity of human non-small cell lung cancer A549 cells via increasing NO production to induce cell cycle arrest at G2/M phase
- (2011) Yanyan Zhao et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- In vitroevaluation of the cytotoxic and genotoxic effects of artemether, an antimalarial drug, in a gastric cancer cell line (PG100)
- (2011) Diego Di Felipe Ávila Alcântara et al. JOURNAL OF APPLIED TOXICOLOGY
- Anti-tumor effects of dihydroartemisinin on human osteosarcoma
- (2011) Ye Ji et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Artesunate Induces Oxidative DNA Damage, Sustained DNA Double-Strand Breaks, and the ATM/ATR Damage Response in Cancer Cells
- (2011) N. Berdelle et al. MOLECULAR CANCER THERAPEUTICS
- The Effects of Artesunate on the Expression of EGFR and ABCG2 in A549 Human Lung Cancer Cells and a Xenograft Model
- (2011) Hu Ma et al. MOLECULES
- The discovery of artemisinin (qinghaosu) and gifts from Chinese medicine
- (2011) Youyou Tu NATURE MEDICINE
- Dihydroartemisinin accelerates c-MYC oncoprotein degradation and induces apoptosis in c-MYC-overexpressing tumor cells
- (2010) Jin-Jian Lu et al. BIOCHEMICAL PHARMACOLOGY
- Dihydroartemisinin induces apoptosis in HL-60 leukemia cells dependent of iron and p38 mitogen-activated protein kinase activation but independent of reactive oxygen species
- (2010) Jin-Jian Lu et al. CANCER BIOLOGY & THERAPY
- In vitro study of the anti-cancer effects of artemisone alone or in combination with other chemotherapeutic agents
- (2010) Andrew M. Gravett et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Dihydroartemisinin inactivates NF-κB and potentiates the anti-tumor effect of gemcitabine on pancreatic cancer both in vitro and in vivo
- (2010) Shuang-Jia Wang et al. CANCER LETTERS
- Artesunate inhibiting angiogenesis induced by human myeloma RPMI8226 cells
- (2010) Hao Chen et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- The Role of Heme and the Mitochondrion in the Chemical and Molecular Mechanisms of Mammalian Cell Death Induced by the Artemisinin Antimalarials
- (2010) Amy E. Mercer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Artesunate Activates Mitochondrial Apoptosis in Breast Cancer Cells via Iron-catalyzed Lysosomal Reactive Oxygen Species Production
- (2010) Anne Hamacher-Brady et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Artesunate mitigates proliferation of tumor cells by alkylating heme-harboring nitric oxide synthase
- (2010) Qing-Ping Zeng et al. NITRIC OXIDE-BIOLOGY AND CHEMISTRY
- Arsenic Trioxide Controls the Fate of the PML-RAR Oncoprotein by Directly Binding PML
- (2010) X. W. Zhang et al. SCIENCE
- The Role of Downstream Signaling Pathways of the Epidermal Growth Factor Receptor for Artesunates Activity in Cancer Cells
- (2009) V. Konkimalla et al. CURRENT CANCER DRUG TARGETS
- Novel Classes of Dimer Antitumour Drug Candidates
- (2009) Larry Chow et al. CURRENT PHARMACEUTICAL DESIGN
- Effect of artesunate on inhibiting proliferation and inducing apoptosis of SP2/0 myeloma cells through affecting NFκB p65
- (2009) Shihui Li et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Growth inhibitory effects of dihydroartemisinin on pancreatic cancer cells: involvement of cell cycle arrest and inactivation of nuclear factor-κB
- (2009) Hua Chen et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Severe Embryotoxicity of Artemisinin Derivatives in Experimental Animals, but Possibly Safe in Pregnant Women
- (2009) Qigui Li et al. MOLECULES
- Transferrin receptor-dependent cytotoxicity of artemisinin–transferrin conjugates on prostate cancer cells and induction of apoptosis
- (2008) Ikuhiko Nakase et al. CANCER LETTERS
- Artesunate Derived from Traditional Chinese Medicine Induces DNA Damage and Repair
- (2008) P. C.H. Li et al. CANCER RESEARCH
- Experimental Therapy of Hepatoma with Artemisinin and Its Derivatives: In vitro and In vivo Activity, Chemosensitization, and Mechanisms of Action
- (2008) J. Hou et al. CLINICAL CANCER RESEARCH
- The Antiviral Activities of Artemisinin and Artesunate
- (2008) Thomas Efferth et al. CLINICAL INFECTIOUS DISEASES
- Differential sensitivity of colorectal cancer cell lines to artesunate is associated with expression of beta-catenin and E-cadherin
- (2008) Lin-Na Li et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Artemisinin Blocks Prostate Cancer Growth and Cell Cycle Progression by Disrupting Sp1 Interactions with the Cyclin-dependent Kinase-4 (CDK4) Promoter and Inhibiting CDK4 Gene Expression
- (2008) Jamin A. Willoughby et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dihydroartemisinin induces apoptosis and sensitizes human ovarian cancer cells to carboplatin therapy
- (2008) Tao Chen et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
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