Irisin Peptide Protects Brain Against Ischemic Injury Through Reducing Apoptosis and Enhancing BDNF in a Rodent Model of Stroke

Serum levels of irisin predict short-term outcomes in ischemic stroke

(2018) Huisheng Wu et al.   CYTOKINE

Neuroprotective nature of adipokine resistin in the early stages of focal cerebral ischemia in a stroke mouse model

(2018) Sedigheh Behrouzifar et al.   NEUROCHEMISTRY INTERNATIONAL

Irisin plays a pivotal role to protect the heart against ischemia and reperfusion injury

(2017) Hao Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The novel exercise-induced hormone irisin protects against neuronal injury via activation of the Akt and ERK1/2 signaling pathways and contributes to the neuroprotection of physical exercise in cerebral ischemia

(2017) Dong-Jie Li et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Irisin protects against neuronal injury induced by oxygen-glucose deprivation in part depends on the inhibition of ROS-NLRP3 inflammatory signaling pathway

(2017) Juan Peng et al.   MOLECULAR IMMUNOLOGY

Effects and underlying mechanisms of irisin on the proliferation and apoptosis of pancreatic β cells

(2017) Shiwei Liu et al.   PLoS One

Alteration of the irisin–brain-derived neurotrophic factor axis contributes to disturbance of mood in COPD patients

(2017) Csaba Papp et al.   International Journal of Chronic Obstructive Pulmonary Disease

Cellular and molecular mechanisms of the brain-derived neurotrophic factor in physiological and pathological conditions

(2016) Veronica Begni et al.   CLINICAL SCIENCE

Novel myokine: irisin may be an independent predictor for subclinic atherosclerosis in Behçet's disease

(2016) Abdullah Icli et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Conjugated linoleic acid rat pretreatment reduces renal damage in ischemia/reperfusion injury: Unraveling antiapoptotic mechanisms and regulation of phosphorylated mammalian target of rapamycin

(2016) Gholamali Javedan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Irisin protects against endothelial injury and ameliorates atherosclerosis in apolipoprotein E-Null diabetic mice

(2015) Junyan Lu et al.   ATHEROSCLEROSIS

Irisin relaxes mouse mesenteric arteries through endothelium-dependent and endothelium-independent mechanisms

(2015) Miao Jiang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effect of the Inhibition of Hydrogen Sulfide Synthesis on Ischemic Injury and Oxidative Stress Biomarkers in a Transient Model of Focal Cerebral Ischemia in Rats

(2015) Maryam Hadadha et al.   Journal of Stroke & Cerebrovascular Diseases

Does PGC1α/FNDC5/BDNF Elicit the Beneficial Effects of Exercise on Neurodegenerative Disorders?

(2015) Mohammad Jodeiri Farshbaf et al.   NEUROMOLECULAR MEDICINE

Effect of the Inhibition of Hydrogen Sulfide Synthesis on Ischemic Injury and Oxidative Stress Biomarkers in a Transient Model of Focal Cerebral Ischemia in Rats

(2015) Maryam Hadadha et al.   Journal of Stroke & Cerebrovascular Diseases

Decreased saliva/serum irisin concentrations in the acute myocardial infarction promising for being a new candidate biomarker for diagnosis of this pathology

(2014) Suna Aydin et al.   PEPTIDES

Irisin: A potentially candidate marker for myocardial infarction

(2014) Tuncay Kuloglu et al.   PEPTIDES

Irisin Promotes Human Umbilical Vein Endothelial Cell Proliferation through the ERK Signaling Pathway and Partly Suppresses High Glucose-Induced Apoptosis

(2014) Haibo Song et al.   PLoS One

Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway

(2013) Christiane D. Wrann et al.   Cell Metabolism

Pharmacological concentrations of irisin increase cell proliferation without influencing markers of neurite outgrowth and synaptogenesis in mouse H19-7 hippocampal cell lines

(2013) Hyun-Seuk Moon et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Irisin-immunoreactivity in neural and non-neural cells of the rodent

(2013) S.L. Dun et al.   NEUROSCIENCE

FNDC5/Irisin Is Not Only a Myokine but Also an Adipokine

(2013) Arturo Roca-Rivada et al.   PLoS One

Irisin, Two Years Later

(2013) Marta G. Novelle et al.   International Journal of Endocrinology

Fndc5 knockdown significantly decreased neural differentiation rate of mouse embryonic stem cells

(2012) M.-S. Hashemi et al.   NEUROSCIENCE

Pentoxifylline attenuates TNF-α protein levels and brain edema following temporary focal cerebral ischemia in rats

(2011) Abedin Vakili et al.   BRAIN RESEARCH