标题
Advances in meningioma genetics: novel therapeutic opportunities
作者
关键词
-
出版物
Nature Reviews Neurology
Volume 14, Issue 2, Pages 106-115
出版商
Springer Nature
发表日期
2018-01-05
DOI
10.1038/nrneurol.2017.168
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeted sequencing of SMO and AKT1 in anterior skull base meningiomas
- (2017) Matthew R. Strickland et al. JOURNAL OF NEUROSURGERY
- DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis
- (2017) Felix Sahm et al. LANCET ONCOLOGY
- Frequent AKT1E17K mutations in skull base meningiomas are associated with mTOR and ERK1/2 activation and reduced time to tumor recurrence
- (2017) Ümmügülsüm Yesilöz et al. NEURO-ONCOLOGY
- BAP1 mutations in high-grade meningioma: implications for patient care
- (2017) Ganesh M Shankar et al. NEURO-ONCOLOGY
- Integrated genomic analyses of de novo pathways underlying atypical meningiomas
- (2017) Akdes Serin Harmancı et al. Nature Communications
- Genomic landscape of high-grade meningiomas
- (2017) Wenya Linda Bi et al. npj Genomic Medicine
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- SomaticAKT1mutations cause meningiomas colocalizing with a characteristic pattern of cranial hyperostosis
- (2016) Kim M. Keppler-Noreuil et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- A phase II trial of bevacizumab and everolimus as treatment for patients with refractory, progressive intracranial meningioma
- (2016) Kent C. Shih et al. JOURNAL OF NEURO-ONCOLOGY
- The Simpson grading revisited: aggressive surgery and its place in modern meningioma management
- (2016) Konstantinos Gousias et al. JOURNAL OF NEUROSURGERY
- EANO guidelines for the diagnosis and treatment of meningiomas
- (2016) Roland Goldbrunner et al. LANCET ONCOLOGY
- Clinical impact of targeted amplicon sequencing for meningioma as a practical clinical-sequencing system
- (2016) Sayaka Yuzawa et al. MODERN PATHOLOGY
- Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas
- (2016) Victoria E Clark et al. NATURE GENETICS
- Oncogenic PI3K mutations are as common asAKT1andSMOmutations in meningioma
- (2016) Malak Abedalthagafi et al. NEURO-ONCOLOGY
- Double-Blind Phase III Randomized Trial of the Antiprogestin Agent Mifepristone in the Treatment of Unresectable Meningioma: SWOG S9005
- (2015) Yongli Ji et al. JOURNAL OF CLINICAL ONCOLOGY
- Meningiomas With Rhabdoid Features Lacking Other Histologic Features of Malignancy: A Study of 44 Cases and Review of the Literature
- (2015) Rachael A. Vaubel et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Meningiomas: knowledge base, treatment outcomes, and uncertainties. A RANO review
- (2015) Leland Rogers et al. JOURNAL OF NEUROSURGERY
- TERT Promoter Mutations and Risk of Recurrence in Meningioma
- (2015) Felix Sahm et al. JNCI-Journal of the National Cancer Institute
- Pathology concordance levels for meningioma classification and grading in NRG Oncology RTOG Trial 0539
- (2015) C. Leland Rogers et al. NEURO-ONCOLOGY
- American Brain Tumor Association Adolescent and Young Adult Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012
- (2015) Quinn T. Ostrom et al. NEURO-ONCOLOGY
- CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012
- (2015) Quinn T. Ostrom et al. NEURO-ONCOLOGY
- Role of Merlin/NF2 inactivation in tumor biology
- (2015) A M Petrilli et al. ONCOGENE
- A high-throughput kinome screen reveals serum/glucocorticoid-regulated kinase 1 as a therapeutic target for NF2-deficient meningiomas
- (2015) Roberta L. Beauchamp et al. Oncotarget
- TERT Promoter Mutations and Risk of Recurrence in Meningioma
- (2015) Felix Sahm et al. JNCI-Journal of the National Cancer Institute
- Analyses of merlin/NF2 connection to FAK inhibitor responsiveness in serous ovarian cancer
- (2014) Nina R. Shah et al. GYNECOLOGIC ONCOLOGY
- Re-evaluation of cytostatic therapies for meningiomas in vitro
- (2014) Annette Wilisch-Neumann et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Germline Mutations inSUFUCause Gorlin Syndrome–Associated Childhood Medulloblastoma and Redefine the Risk Associated WithPTCH1Mutations
- (2014) Miriam J. Smith et al. JOURNAL OF CLINICAL ONCOLOGY
- GermlineSMARCE1mutations predispose to both spinal and cranial clear cell meningiomas
- (2014) Miriam J Smith et al. JOURNAL OF PATHOLOGY
- Targeted treatment for sonic hedgehog-dependent medulloblastoma
- (2014) M. W. Kieran NEURO-ONCOLOGY
- Historical benchmarks for medical therapy trials in surgery- and radiation-refractory meningioma: a RANO review
- (2014) T. Kaley et al. NEURO-ONCOLOGY
- Phase II trial of sunitinib for recurrent and progressive atypical and anaplastic meningioma
- (2014) Thomas J. Kaley et al. NEURO-ONCOLOGY
- Phase II study of monthly pasireotide LAR (SOM230C) for recurrent or progressive meningioma
- (2014) A. D. Norden et al. NEUROLOGY
- Immunohistochemical analysis of cyclooxygenase-2 and brain fatty acid binding protein expression in grades I-II meningiomas: Correlation with tumor grade and clinical outcome after radiotherapy
- (2014) Hyun-Cheol Kang et al. NEUROPATHOLOGY
- Merlin Deficiency Predicts FAK Inhibitor Sensitivity: A Synthetic Lethal Relationship
- (2014) I. M. Shapiro et al. Science Translational Medicine
- Complex interactions between the components of the PI3K/AKT/mTOR pathway, and with components of MAPK, JAK/STAT and Notch-1 pathways, indicate their involvement in meningioma development
- (2014) Elias A. El-Habr et al. VIRCHOWS ARCHIV
- AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry
- (2013) Felix Sahm et al. ACTA NEUROPATHOLOGICA
- Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations
- (2013) David E. Reuss et al. ACTA NEUROPATHOLOGICA
- High Incidence of ActivatingTERTPromoter Mutations in Meningiomas Undergoing Malignant Progression
- (2013) Stéphane Goutagny et al. BRAIN PATHOLOGY
- Role of Macrophage Targeting in the Antitumor Activity of Trabectedin
- (2013) Giovanni Germano et al. CANCER CELL
- mTORC1 Inhibitors Suppress Meningioma Growth in Mouse Models
- (2013) D. Pachow et al. CLINICAL CANCER RESEARCH
- Mobile phone use and risk of brain neoplasms and other cancers: prospective study
- (2013) Victoria S Benson et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Loss-of-function mutations in SMARCE1 cause an inherited disorder of multiple spinal meningiomas
- (2013) Miriam J Smith et al. NATURE GENETICS
- Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations
- (2013) Priscilla K Brastianos et al. NATURE GENETICS
- Genomic Analysis of Non-NF2 Meningiomas Reveals Mutations in TRAF7, KLF4, AKT1, and SMO
- (2013) V. E. Clark et al. SCIENCE
- Trabectedin has promising antineoplastic activity in high-grade meningioma
- (2012) Matthias Preusser et al. CANCER
- Exogenous hormone use, reproductive factors, and risk of intracranial meningioma in females
- (2012) Elizabeth B. Claus et al. JOURNAL OF NEUROSURGERY
- Regulation of mTOR Complex 2 Signaling in Neurofibromatosis 2-Deficient Target Cell Types
- (2012) M. F. James et al. MOLECULAR CANCER RESEARCH
- The structure of the Klf4 DNA-binding domain links to self-renewal and macrophage differentiation
- (2011) Anja Schuetz et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Comparative morphological and immunohistochemical study of human meningioma after intracranial transplantation into nude mice
- (2011) Sabrina Friedrich et al. JOURNAL OF NEUROSCIENCE METHODS
- Family and personal medical history and risk of meningioma
- (2011) Elizabeth B. Claus et al. JOURNAL OF NEUROSURGERY
- Possible interaction between ionizing radiation, smoking, and gender in the causation of meningioma
- (2011) P. Flint-Richter et al. NEURO-ONCOLOGY
- Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes
- (2011) M Kalamarides et al. ONCOGENE
- Genomic Profiling Reveals Alternative Genetic Pathways of Meningioma Malignant Progression Dependent on the Underlying NF2 Status
- (2010) S. Goutagny et al. CLINICAL CANCER RESEARCH
- Improved Correlation of the Neuropathologic Classification According to Adapted World Health Organization Classification and Outcome After Radiotherapy in Patients With Atypical and Anaplastic Meningiomas
- (2010) Stephanie E. Combs et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Analysis of transforming growth factor β receptor expression and signaling in higher grade meningiomas
- (2010) Mahlon D. Johnson et al. JOURNAL OF NEURO-ONCOLOGY
- Pathological classification and molecular genetics of meningiomas
- (2010) Christian Mawrin et al. JOURNAL OF NEURO-ONCOLOGY
- Medical therapies for meningiomas
- (2010) Patrick Y. Wen et al. JOURNAL OF NEURO-ONCOLOGY
- Unknown
- (2010) Ingrid Laurendeau et al. MOLECULAR MEDICINE
- Mammalian Krüppel-Like Factors in Health and Diseases
- (2010) Beth B. McConnell et al. PHYSIOLOGICAL REVIEWS
- Bone Morphogenetic Protein 4 and Its Receptors Are Expressed in the Leptomeninges and Meningiomas and Signal via the Smad Pathway
- (2009) Mahlon D. Johnson et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Loss of the Tumor Suppressor Gene NF2, Encoding Merlin, Constitutively Activates Integrin-Dependent mTORC1 Signaling
- (2009) M. A. Lopez-Lago et al. MOLECULAR AND CELLULAR BIOLOGY
- NF2/Merlin Is a Novel Negative Regulator of mTOR Complex 1, and Activation of mTORC1 Is Associated with Meningioma and Schwannoma Growth
- (2009) M. F. James et al. MOLECULAR AND CELLULAR BIOLOGY
- CORRESPONDENCE OF TUMOR LOCALIZATION WITH TUMOR RECURRENCE AND CYTOGENETIC PROGRESSION IN MENINGIOMAS
- (2009) Ralf Ketter et al. NEUROSURGERY
- Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma
- (2009) Daniel D. Von Hoff et al. NEW ENGLAND JOURNAL OF MEDICINE
- Hitting a moving target: evolution of a treatment paradigm for atypical meningiomas amid changing diagnostic criteria
- (2008) Blake E. Pearson et al. Neurosurgical Focus
- A comparison of the cell lines used in meningioma research
- (2008) Brian T. Ragel et al. SURGICAL NEUROLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More