Identifying key membrane protein lipid interactions using mass spectrometry

Protein–phospholipid interplay revealed with crystals of a calcium pump

(2017) Yoshiyuki Norimatsu et al.   NATURE

The role of interfacial lipids in stabilizing membrane protein oligomers

(2017) Kallol Gupta et al.   NATURE

Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters

(2017) Michael Landreh et al.   Nature Communications

Native MS Analysis of Bacteriorhodopsin and an Empty Nanodisc by Orthogonal Acceleration Time-of-Flight, Orbitrap and Ion Cyclotron Resonance

(2016) Iain D. G. Campuzano et al.   ANALYTICAL CHEMISTRY

Lipid interaction sites on channels, transporters and receptors: Recent insights from molecular dynamics simulations

(2016) George Hedger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

A sliding selectivity scale for lipid binding to membrane proteins

(2016) Michael Landreh et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Native Mass Spectrometry Characterizes the Photosynthetic Reaction Center Complex from the Purple Bacterium Rhodobacter sphaeroides

(2016) Hao Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Negative Ions Enhance Survival of Membrane Protein Complexes

(2016) Idlir Liko et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Mass spectrometry captures off-target drug binding and provides mechanistic insights into the human metalloprotease ZMPSTE24

(2016) Shahid Mehmood et al.   Nature Chemistry

High-resolution mass spectrometry of small molecules bound to membrane proteins

(2016) Joseph Gault et al.   NATURE METHODS

Dimer interface of bovine cytochromecoxidase is influenced by local posttranslational modifications and lipid binding

(2016) Idlir Liko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM

(2016) Matthew G. Iadanza et al.   Nature Communications

A subset of annular lipids is linked to the flippase activity of an ABC transporter

(2015) Chérine Bechara et al.   Nature Chemistry

MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis

(2015) Hiroshi Tsugawa et al.   NATURE METHODS

Tight binding of NAP-22 with acidic membrane lipids

(2015) Shohei Maekawa et al.   NEUROSCIENCE LETTERS

Quantifying the stabilizing effects of protein–ligand interactions in the gas phase

(2015) Timothy M. Allison et al.   Nature Communications

Variation of the Detergent-Binding Capacity and Phospholipid Content of Membrane Proteins When Purified in Different Detergents

(2014) Hüseyin Ilgü et al.   BIOPHYSICAL JOURNAL

Charge Reduction Stabilizes Intact Membrane Protein Complexes for Mass Spectrometry

(2014) Shahid Mehmood et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Purification and interaction analyses of two human lysosomal vitamin B12transporters: LMBD1 and ABCD4

(2014) Justin C. Deme et al.   MOLECULAR MEMBRANE BIOLOGY

Global structural changes of an ion channel during its gating are followed by ion mobility mass spectrometry

(2014) Albert Konijnenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mass spectrometry of intact membrane protein complexes

(2013) Arthur Laganowsky et al.   Nature Protocols

Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pump

(2013) J. Marcoux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mass Spectrometry of Intact V-Type ATPases Reveals Bound Lipids and the Effects of Nucleotide Binding

(2011) M. Zhou et al.   SCIENCE

Lipidomics Profiling by High-Resolution LC−MS and High-Energy Collisional Dissociation Fragmentation: Focus on Characterization of Mitochondrial Cardiolipins and Monolysocardiolipins

(2010) Susan S. Bird et al.   ANALYTICAL CHEMISTRY

Micelles Protect Membrane Complexes from Solution to Vacuum

(2008) N. P. Barrera et al.   SCIENCE