Embryonic defects induced by maternal obesity in mice derive from Stella insufficiency in oocytes

A Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic Reprogramming

(2016) Sabrina Ladstätter et al.   CELL

Detection of differential DNA methylation in repetitive DNA of mice and humans perinatally exposed to bisphenol A

(2016) Christopher Faulk et al.   Epigenetics

5-Hydroxymethylcytosine-mediated alteration of transposon activity associated with the exposure to adversein uteroenvironments in human

(2016) Miao Sun et al.   HUMAN MOLECULAR GENETICS

De novo DNA methylation drives 5hmC accumulation in mouse zygotes

(2016) Rachel Amouroux et al.   NATURE CELL BIOLOGY

Epigenetic germline inheritance of diet-induced obesity and insulin resistance

(2016) Peter Huypens et al.   NATURE GENETICS

5-Hydroxymethylcytosine Marks Sites of DNA Damage and Promotes Genome Stability

(2016) Georgia Rose Kafer et al.   Cell Reports

Maternal Metabolic Syndrome Programs Mitochondrial Dysfunction via Germline Changes across Three Generations

(2016) Jessica L. Saben et al.   Cell Reports

When two obese parents are worse than one! Impacts on embryo and fetal development

(2015) N. O. McPherson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

I’m Eating for Two: Parental Dietary Effects on Offspring Metabolism

(2015) Oliver J. Rando et al.   CELL

Sirt3 prevents maternal obesity-associated oxidative stress and meiotic defects in mouse oocytes

(2015) Liang Zhang et al.   CELL CYCLE

Mitochondrial dysfunction in oocytes of obese mothers: transmission to offspring and reversal by pharmacological endoplasmic reticulum stress inhibitors

(2015) L. L. Wu et al.   DEVELOPMENT

Stella preserves maternal chromosome integrity by inhibiting 5hmC-induced  H2AX accumulation

(2015) T. Nakatani et al.   EMBO REPORTS

metilene: fast and sensitive calling of differentially methylated regions from bisulfite sequencing data

(2015) Frank Jühling et al.   GENOME RESEARCH

Combined parental obesity negatively impacts preimplantation mouse embryo development, kinetics, morphology and metabolism

(2015) Bethany J. Finger et al.   HUMAN REPRODUCTION

Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation

(2015) X. Hou et al.   JOURNAL OF CELL SCIENCE

Quantitative Phosphoproteomics Analysis Reveals a Key Role of Insulin Growth Factor 1 Receptor (IGF1R) Tyrosine Kinase in Human Sperm Capacitation

(2015) Jing Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

Maternal obesity in females born small: Pregnancy complications and offspring disease risk

(2015) Dayana Mahizir et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The UCSC Genome Browser database: 2016 update

(2015) Matthew L. Speir et al.   NUCLEIC ACIDS RESEARCH

Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation

(2015) Nuala A. O'Leary et al.   NUCLEIC ACIDS RESEARCH

Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth

(2015) Irving L. M. H. Aye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intergenerational epigenetic inheritance in models of developmental programming of adult disease

(2015) Denise S. Fernandez-Twinn et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Maternal TET3 is dispensable for embryonic development but is required for neonatal growth

(2015) Yu-ichi Tsukada et al.   Scientific Reports

Haploinsufficiency, but Not Defective Paternal 5mC Oxidation, Accounts for the Developmental Defects of Maternal Tet3 Knockouts

(2015) Azusa Inoue et al.   Cell Reports

Effects of Maternal Obesity on Fetal Programming: Molecular Approaches

(2015) Caterina Neri et al.   Cold Spring Harbor Perspectives in Medicine

Inhibition of maintenance DNA methylation by Stella

(2014) Soichiro Funaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pre-gestational vs gestational exposure to maternal obesity differentially programs the offspring in mice

(2014) Isaac E. Sasson et al.   DIABETOLOGIA

Systematic Analysis of the Phosphoproteome and Kinase-substrate Networks in the Mouse Testis

(2014) Lin Qi et al.   MOLECULAR & CELLULAR PROTEOMICS

Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity

(2014) Sébastien A Smallwood et al.   NATURE METHODS

Impact of Maternal Obesity on Fetal Health

(2013) Kinneret Tenenbaum-Gavish et al.   FETAL DIAGNOSIS AND THERAPY

Maternal obesity, infertility and mitochondrial dysfunction: potential mechanisms emerging from mouse model systems

(2013) N. M. Grindler et al.   MOLECULAR HUMAN REPRODUCTION

Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b

(2013) Jan-Wilhelm Kornfeld et al.   NATURE

PGC7 suppresses TET3 for protecting DNA methylation

(2013) C. Bian et al.   NUCLEIC ACIDS RESEARCH

CRL4 Complex Regulates Mammalian Oocyte Survival and Reprogramming by Activation of TET Proteins

(2013) C. Yu et al.   SCIENCE

Independent risk factors for infants who are small for gestational age by customised birthweight centiles in a multi-ethnic New Zealand population

(2012) Ngaire H. Anderson et al.   AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY

PGC7, H3K9me2 and Tet3: regulators of DNA methylation in zygotes

(2012) Jinsuk Kang et al.   CELL RESEARCH

Effect of maternal obesity on estrous cyclicity, embryo development and blastocyst gene expression in a mouse model

(2012) P. Bermejo-Alvarez et al.   HUMAN REPRODUCTION

PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos

(2012) Toshinobu Nakamura et al.   NATURE

High Fat Diet Induced Developmental Defects in the Mouse: Oocyte Meiotic Aneuploidy and Fetal Growth Retardation/Brain Defects

(2012) Kerri M. Luzzo et al.   PLoS One

The effect of increasing obesity on the response to and outcome of assisted reproductive technology: a national study

(2011) Barbara Luke et al.   FERTILITY AND STERILITY

The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

(2011) Tian-Peng Gu et al.   NATURE

Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine

(2011) Khursheed Iqbal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes

(2010) Mark Wossidlo et al.   EMBO JOURNAL

Diet-Induced Obesity Model: Abnormal Oocytes and Persistent Growth Abnormalities in the Offspring

(2010) Emily S. Jungheim et al.   ENDOCRINOLOGY

Maternal Diet-Induced Obesity Alters Mitochondrial Activity and Redox Status in Mouse Oocytes and Zygotes

(2010) Natalia Igosheva et al.   PLoS One

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice

(2008) Helen N. Jones et al.   FASEB JOURNAL

One-Cell Zygote Transfer from Diabetic to Nondiabetic Mouse Results in Congenital Malformations and Growth Retardation in Offspring

(2007) Amanda Wyman et al.   ENDOCRINOLOGY