Epigenetic germline inheritance of diet-induced obesity and insulin resistance

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics

(2015) Martin Hrabě de Angelis et al.   NATURE GENETICS

Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder

(2015) Q. Chen et al.   SCIENCE

Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals

(2015) U. Sharma et al.   SCIENCE

RNA-mediated paternal heredity of diet-induced obesity and metabolic disorders

(2015) Valérie Grandjean et al.   Scientific Reports

Neonatal Insulin Action Impairs Hypothalamic Neurocircuit Formation in Response to Maternal High-Fat Feeding

(2014) Merly C. Vogt et al.   CELL

Pre-gestational vs gestational exposure to maternal obesity differentially programs the offspring in mice

(2014) Isaac E. Sasson et al.   DIABETOLOGIA

INFRAFRONTIER--providing mutant mouse resources as research tools for the international scientific community

(2014)   NUCLEIC ACIDS RESEARCH

High Fat Diet and In Utero Exposure to Maternal Obesity Disrupts Circadian Rhythm and Leads to Metabolic Programming of Liver in Rat Offspring

(2014) Sarah J. Borengasser et al.   PLoS One

Paternally induced transgenerational inheritance of susceptibility to diabetes in mammals

(2014) Yanchang Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maternal tract factors contribute to paternal seminal fluid impact on metabolic phenotype in offspring

(2014) John J. Bromfield et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maternal Obesity Enhances White Adipose Tissue Differentiation and Alters Genome-Scale DNA Methylation in Male Rat Offspring

(2013) Sarah J. Borengasser et al.   ENDOCRINOLOGY

Paternal obesity initiates metabolic disturbances in two generations of mice with incomplete penetrance to the F2 generation and alters the transcriptional profile of testis and sperm microRNA content

(2013) Tod Fullston et al.   FASEB JOURNAL

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Trends in the association of parental history of obesity over 60 years

(2013) Caroline S. Fox et al.   Obesity

Maternal High-Fat Diet During Gestation or Suckling Differentially Affects Offspring Leptin Sensitivity and Obesity

(2012) B. Sun et al.   DIABETES

Maternal Obesity Promotes a Proinflammatory Signature in Rat Uterus and Blastocyst

(2011) Kartik Shankar et al.   ENDOCRINOLOGY

Maternal Overweight Programs Insulin and Adiponectin Signaling in the Offspring

(2010) Kartik Shankar et al.   ENDOCRINOLOGY

Epigenetics and the origins of paternal effects

(2010) James P. Curley et al.   HORMONES AND BEHAVIOR

Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring

(2010) Sheau-Fang Ng et al.   NATURE

Towards better mouse models: enhanced genotypes, systemic phenotyping and envirotype modelling

(2009) Johannes Beckers et al.   NATURE REVIEWS GENETICS

The thrifty epigenotype: An acquired and heritable predisposition for obesity and diabetes?

(2008) Reinhard Stöger   BIOESSAYS

Maternal obesity at conception programs obesity in the offspring

(2007) Kartik Shankar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY