Features and regulation of non-enzymatic post-translational modifications

Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes

(2018) Rahul S. Kathayat et al.   Nature Communications

Inositol hexakisphosphate kinase 1 (IP6K1) activity is required for cytoplasmic dynein-driven transport

(2016) M. Chanduri et al.   BIOCHEMICAL JOURNAL

Cellular Cations Control Conformational Switching of Inositol Pyrophosphate Analogues

(2016) Anastasia Hager et al.   CHEMISTRY-A EUROPEAN JOURNAL

Site-Specific Reactivity of Nonenzymatic Lysine Acetylation

(2015) Josue Baeza et al.   ACS Chemical Biology

Regulation of Protein Function by Reversible Methionine Oxidation and the Role of Selenoprotein MsrB1

(2015) Alaattin Kaya et al.   ANTIOXIDANTS & REDOX SIGNALING

Establishing the Stability and Reversibility of Protein Pyrophosphorylation with Synthetic Peptides

(2015) Lisa M. Yates et al.   CHEMBIOCHEM

The widespread role of non-enzymatic reactions in cellular metabolism

(2015) Markus A Keller et al.   CURRENT OPINION IN BIOTECHNOLOGY

Protein carbamylation and cardiovascular disease

(2015) Frederik H. Verbrugge et al.   KIDNEY INTERNATIONAL

Protein Polyphosphorylation of Lysine Residues by Inorganic Polyphosphate

(2015) Cristina Azevedo et al.   MOLECULAR CELL

Protein Carbamylation in Kidney Disease: Pathogenesis and Clinical Implications

(2014) Sahir Kalim et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Elucidating Diphosphoinositol Polyphosphate Function with Nonhydrolyzable Analogues

(2014) Mingxuan Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The physiological role of reversible methionine oxidation

(2014) Adrian Drazic et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Lysine Glutarylation Is a Protein Posttranslational Modification Regulated by SIRT5

(2014) Minjia Tan et al.   Cell Metabolism

An overview of mechanisms of redox signaling

(2014) Henry Jay Forman et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Nonenzymatic Protein Acylation as a Carbon Stress Regulated by Sirtuin Deacylases

(2014) Gregory R. Wagner et al.   MOLECULAR CELL

Hydrogen peroxide signaling in vascular endothelial cells

(2014) Rosa Bretón-Romero et al.   Redox Biology

Characterization of a cellular denitrase activity that reverses nitration of cyclooxygenase

(2013) Ruba S. Deeb et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery

(2013) Candice E. Paulsen et al.   CHEMICAL REVIEWS

Cysteine Oxidative Posttranslational Modifications

(2013) Heaseung S. Chung et al.   CIRCULATION RESEARCH

Widespread and Enzyme-independentNϵ-Acetylation andNϵ-Succinylation of Proteins in the Chemical Conditions of the Mitochondrial Matrix

(2013) Gregory R. Wagner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolution and functional cross-talk of protein post-translational modifications

(2013) Pedro Beltrao et al.   Molecular Systems Biology

Rare insights into cancer biology

(2013) J Adam et al.   ONCOGENE

Methionine oxidation activates a transcription factor in response to oxidative stress

(2013) Adrian Drazic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Lysine Modification by an Intrinsically Reactive Primary Glycolytic Metabolite

(2013) R. E. Moellering et al.   SCIENCE

Protein Lysine Acylation and Cysteine Succination by Intermediates of Energy Metabolism

(2012) Hening Lin et al.   ACS Chemical Biology

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling

(2011) Julie Adam et al.   CANCER CELL

Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status

(2011) Chiara Bardella et al.   JOURNAL OF PATHOLOGY

Chemistry and biology of reactive oxygen species in signaling or stress responses

(2011) Bryan C Dickinson et al.   Nature Chemical Biology

Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase

(2011) J. Du et al.   SCIENCE

Inositol Pyrophosphates Inhibit Akt Signaling, Thereby Regulating Insulin Sensitivity and Weight Gain

(2010) Anutosh Chakraborty et al.   CELL

Evaluation of Nonenzymatic Posttranslational Modification-Derived Products as Biomarkers of Molecular Aging of Proteins

(2010) S. Jaisson et al.   CLINICAL CHEMISTRY

Identifying peroxidases and their oxidants in the early pathology of cystic fibrosis

(2010) Eline Thomson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Succination of proteins in diabetes

(2010) Norma Frizzell et al.   FREE RADICAL RESEARCH

Proteomic Identification of Carbonylated Proteins and Their Oxidation Sites

(2010) Ashraf G. Madian et al.   JOURNAL OF PROTEOME RESEARCH

Identification of lysine succinylation as a new post-translational modification

(2010) Zhihong Zhang et al.   Nature Chemical Biology

Inositol pyrophosphate mediated pyrophosphorylation of AP3B1 regulates HIV-1 Gag release

(2009) Cristina Azevedo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H2S Signals Through Protein S-Sulfhydration

(2009) A. K. Mustafa et al.   Science Signaling

Succination of Proteins by Fumarate

(2008) Matthew Blatnik et al.   Annals of the New York Academy of Sciences

Loss of Keap1 Function Activates Nrf2 and Provides Advantages for Lung Cancer Cell Growth

(2008) T. Ohta et al.   CANCER RESEARCH

Quantitative Analysis of global Ubiquitination in HeLa Cells by Mass Spectrometry

(2008) David Meierhofer et al.   JOURNAL OF PROTEOME RESEARCH