Precise, automated control of conditions for high-throughput growth of yeast and bacteria with eVOLVER

Genomics of cellular proliferation in periodic environmental fluctuations

(2018) Jérôme Salignon et al.   Molecular Systems Biology

Experimental Evolution Reveals Favored Adaptive Routes to Cell Aggregation in Yeast

(2017) Elyse A. Hope et al.   GENETICS

The Internet of Things comes to the lab

(2017) Jeffrey M. Perkel   NATURE

The DIY electronics transforming research

(2017) Daniel Cressey   NATURE

Open-source, community-driven microfluidics with Metafluidics

(2017) David S Kong et al.   NATURE BIOTECHNOLOGY

Design of a synthetic yeast genome

(2017) Sarah M. Richardson et al.   SCIENCE

Experimental Evolution Reveals Favored Adaptive Routes to Cell Aggregation in Yeast

(2017) Elyse A. Hope et al.   GENETICS

Design and synthesis of a minimal bacterial genome

(2016) C. A. Hutchison et al.   SCIENCE

On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system

(2016) A. Adamo et al.   SCIENCE

Automated optogenetic feedback control for precise and robust regulation of gene expression and cell growth

(2016) Andreas Milias-Argeitis et al.   Nature Communications

In vivo continuous evolution of genes and pathways in yeast

(2016) Nathan Crook et al.   Nature Communications

Adaptation, Clonal Interference, and Frequency-Dependent Interactions in a Long-Term Evolution Experiment with Escherichia coli

(2015) Rohan Maddamsetti et al.   GENETICS

Stress-response balance drives the evolution of a network module and its host genome

(2015) C. Gonzalez et al.   Molecular Systems Biology

Galactose metabolic genes in yeast respond to a ratio of galactose and glucose

(2015) Renan Escalante-Chong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The concept of fitness in fluctuating environments

(2015) Bernt-Erik Sæther et al.   TRENDS IN ECOLOGY & EVOLUTION

Adaptation, Clonal Interference, and Frequency-Dependent Interactions in a Long-Term Evolution Experiment with Escherichia coli

(2015) Rohan Maddamsetti et al.   GENETICS

The Yeast Deletion Collection: A Decade of Functional Genomics

(2014) Guri Giaever et al.   GENETICS

The enduring utility of continuous culturing in experimental evolution

(2014) David Gresham et al.   GENOMICS

An orthogonal DNA replication system in yeast

(2014) Arjun Ravikumar et al.   Nature Chemical Biology

Dynamic characterization of growth and gene expression using high-throughput automated flow cytometry

(2014) Ignacio A Zuleta et al.   NATURE METHODS

Global epistasis makes adaptation predictable despite sequence-level stochasticity

(2014) S. Kryazhimskiy et al.   SCIENCE

A Low Cost, Customizable Turbidostat for Use in Synthetic Circuit Characterization

(2014) Chris N. Takahashi et al.   ACS Synthetic Biology

Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populations

(2013) Gregory I. Lang et al.   NATURE

Building a morbidostat: an automated continuous-culture device for studying bacterial drug resistance under dynamically sustained drug inhibition

(2013) Erdal Toprak et al.   Nature Protocols

Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes

(2013) P. A. Gibney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromosomal duplication is a transient evolutionary solution to stress

(2012) A. H. Yona et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping the Environmental Fitness Landscape of a Synthetic Gene Circuit

(2012) Dmitry Nevozhay et al.   PLoS Computational Biology

The Response to Heat Shock and Oxidative Stress in Saccharomyces cerevisiae

(2011) K. A. Morano et al.   GENETICS

A system for the continuous directed evolution of biomolecules

(2011) Kevin M. Esvelt et al.   NATURE

Systematic exploration of essential yeast gene function with temperature-sensitive mutants

(2011) Zhijian Li et al.   NATURE BIOTECHNOLOGY

Evolutionary paths to antibiotic resistance under dynamically sustained drug selection

(2011) Erdal Toprak et al.   NATURE GENETICS

Saccharomyces Genome Database: the genomics resource of budding yeast

(2011) J. M. Cherry et al.   NUCLEIC ACIDS RESEARCH

Phenotypic Landscape of a Bacterial Cell

(2010) Robert J. Nichols et al.   CELL

The renaissance of continuous culture in the post-genomics age

(2010) Alan T. Bull   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Quantitative phenotyping via deep barcode sequencing

(2009) A. M. Smith et al.   GENOME RESEARCH

Adaptive prediction of environmental changes by microorganisms

(2009) Amir Mitchell et al.   NATURE

Programming cells by multiplex genome engineering and accelerated evolution

(2009) Harris H. Wang et al.   NATURE

Metabolic gene regulation in a dynamically changing environment

(2008) Matthew R. Bennett et al.   NATURE

Reconstruction of biochemical networks in microorganisms

(2008) Adam M. Feist et al.   NATURE REVIEWS MICROBIOLOGY