标题
The landscape of genomic alterations across childhood cancers
作者
关键词
-
出版物
NATURE
Volume 555, Issue 7696, Pages 321-327
出版商
Springer Nature
发表日期
2018-02-28
DOI
10.1038/nature25480
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mutational signature analysis identifies MUTYH deficiency in colorectal cancers and adrenocortical carcinomas
- (2017) Camilla Pilati et al. JOURNAL OF PATHOLOGY
- The whole-genome landscape of medulloblastoma subtypes
- (2017) Paul A. Northcott et al. NATURE
- Cancer statistics, 2016
- (2016) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes
- (2016) Pascal D. Johann et al. CANCER CELL
- Implementation of mechanism of action biology-driven early drug development for children with cancer
- (2016) Andrew D.J. Pearson et al. EUROPEAN JOURNAL OF CANCER
- Next-generation personalised medicine for high-risk paediatric cancer patients – The INFORM pilot study
- (2016) Barbara C. Worst et al. EUROPEAN JOURNAL OF CANCER
- Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency
- (2016) Eric Bouffet et al. JOURNAL OF CLINICAL ONCOLOGY
- Use of poly ADP-ribose polymerase [PARP] inhibitors in cancer cells bearing DDR defects: the rationale for their inclusion in the clinic
- (2016) Aniello Cerrato et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The genomic landscape of core-binding factor acute myeloid leukemias
- (2016) Zachary J Faber et al. NATURE GENETICS
- Recurrent MET fusion genes represent a drug target in pediatric glioblastoma
- (2016) NATURE MEDICINE
- TP53 germline mutation may affect response to anticancer treatments: analysis of an intensively treated Li–Fraumeni family
- (2015) Sonja Kappel et al. BREAST CANCER RESEARCH AND TREATMENT
- Mutations in the SIX1/2 Pathway and the DROSHA/DGCR8 miRNA Microprocessor Complex Underlie High-Risk Blastemal Type Wilms Tumors
- (2015) Jenny Wegert et al. CANCER CELL
- Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups
- (2015) Kristian W. Pajtler et al. CANCER CELL
- Deep Sequencing in Conjunction with Expression and Functional Analyses Reveals Activation of FGFR1 in Ewing Sarcoma
- (2015) K. Agelopoulos et al. CLINICAL CANCER RESEARCH
- Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation
- (2015) J. B. Kunz et al. HAEMATOLOGICA
- A cell-based model system links chromothripsis with hyperploidy
- (2015) B. R. Mardin et al. Molecular Systems Biology
- Data analysis: Create a cloud commons
- (2015) Lincoln D. Stein et al. NATURE
- An integrated map of structural variation in 2,504 human genomes
- (2015) Peter H. Sudmant et al. NATURE
- A global reference for human genetic variation
- (2015) Richard A. Gibbs et al. NATURE
- TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors
- (2015) Linda J Valentijn et al. NATURE GENETICS
- The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias
- (2015) Anna K Andersson et al. NATURE GENETICS
- Clock-like mutational processes in human somatic cells
- (2015) Ludmil B Alexandrov et al. NATURE GENETICS
- Mutant PRPS1: a new therapeutic target in relapsed acute lymphoblastic leukemia
- (2015) Charles G Mullighan NATURE MEDICINE
- Negative feedback–defective PRPS1 mutants drive thiopurine resistance in relapsed childhood ALL
- (2015) Benshang Li et al. NATURE MEDICINE
- Germline Mutations in Predisposition Genes in Pediatric Cancer
- (2015) Jinghui Zhang et al. NEW ENGLAND JOURNAL OF MEDICINE
- Exome sequencing of osteosarcoma reveals mutation signatures reminiscent of BRCA deficiency
- (2015) Michal Kovac et al. Nature Communications
- Genomic landscape of paediatric adrenocortical tumours
- (2015) Emilia M. Pinto et al. Nature Communications
- Age-related somatic mutations in the cancer genome
- (2015) Brandon Milholland et al. Oncotarget
- Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation
- (2015) J. B. Kunz et al. HAEMATOLOGICA
- Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition
- (2014) J. Irving et al. BLOOD
- Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition
- (2014) Marcel Kool et al. CANCER CELL
- The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acute lymphoblastic leukemia and confers a higher risk of relapse
- (2014) O. R. Bandapalli et al. HAEMATOLOGICA
- The genomic landscape of hepatoblastoma and their progenies with HCC-like features
- (2014) Melanie Eichenmüller et al. JOURNAL OF HEPATOLOGY
- Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
- (2014) Paul A. Northcott et al. NATURE
- Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
- (2014) S. C. Mack et al. NATURE
- C11orf95–RELA fusions drive oncogenic NF-κB signalling in ependymoma
- (2014) Matthew Parker et al. NATURE
- Assessing the clinical utility of cancer genomic and proteomic data across tumor types
- (2014) Yuan Yuan et al. NATURE BIOTECHNOLOGY
- The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
- (2014) Gang Wu et al. NATURE GENETICS
- Alex's Lemonade Stand Foundation Infant and Childhood Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2007–2011
- (2014) Quinn T. Ostrom et al. NEURO-ONCOLOGY
- The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes
- (2014) Robert Huether et al. Nature Communications
- Recurrent Somatic Structural Variations Contribute to Tumorigenesis in Pediatric Osteosarcoma
- (2014) Xiang Chen et al. Cell Reports
- Polycomb group gene BMI1 controls invasion of medulloblastoma cells and inhibits BMP-regulated cell adhesion
- (2014) Ashirwad Merve et al. Acta Neuropathologica Communications
- Targeting Oxidative Stress in Embryonal Rhabdomyosarcoma
- (2013) Xiang Chen et al. CANCER CELL
- Criteria for Inference of Chromothripsis in Cancer Genomes
- (2013) Jan O. Korbel et al. CELL
- Tumor Protein p53 (TP53) Testing and Li-Fraumeni Syndrome
- (2013) April D. Sorrell et al. Molecular Diagnosis & Therapy
- Integrated genomic characterization of endometrial carcinoma
- (2013) Gad Getz et al. NATURE
- Mutational landscape and significance across 12 major cancer types
- (2013) Cyriac Kandoth et al. NATURE
- Signatures of mutational processes in human cancer
- (2013) Ludmil B. Alexandrov et al. NATURE
- The genomic landscape of hypodiploid acute lymphoblastic leukemia
- (2013) Linda Holmfeldt et al. NATURE GENETICS
- Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
- (2013) David T W Jones et al. NATURE GENETICS
- Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas
- (2013) NATURE GENETICS
- Pan-cancer patterns of somatic copy number alteration
- (2013) Travis I Zack et al. NATURE GENETICS
- Emerging landscape of oncogenic signatures across human cancers
- (2013) Giovanni Ciriello et al. NATURE GENETICS
- Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL
- (2013) Gannie Tzoneva et al. NATURE MEDICINE
- IntOGen-mutations identifies cancer drivers across tumor types
- (2013) Abel Gonzalez-Perez et al. NATURE METHODS
- Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness
- (2013) M Tamura et al. ONCOGENE
- Mutationmapper: A Tool to Aid the Mapping of Protein Mutation Data
- (2013) Shabana Vohra et al. PLoS One
- Comprehensive identification of mutational cancer driver genes across 12 tumor types
- (2013) David Tamborero et al. Scientific Reports
- Common Fragile Site Profiling in Epithelial and Erythroid Cells Reveals that Most Recurrent Cancer Deletions Lie in Fragile Sites Hosting Large Genes
- (2013) Benoît Le Tallec et al. Cell Reports
- Deciphering Signatures of Mutational Processes Operative in Human Cancer
- (2013) Ludmil B. Alexandrov et al. Cell Reports
- Late Effects in Adult Survivors of Pediatric Cancer: A Guide for the Primary Care Physician
- (2012) Lisa M. Kopp et al. AMERICAN JOURNAL OF MEDICINE
- DELLY: structural variant discovery by integrated paired-end and split-read analysis
- (2012) T. Rausch et al. BIOINFORMATICS
- An Inv(16)(p13.3q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein Defines an Aggressive Subtype of Pediatric Acute Megakaryoblastic Leukemia
- (2012) Tanja A. Gruber et al. CANCER CELL
- Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations
- (2012) Tobias Rausch et al. CELL
- MuSiC: Identifying mutational significance in cancer genomes
- (2012) N. D. Dees et al. GENOME RESEARCH
- Association of Age at Diagnosis and Genetic Mutations in Patients With Neuroblastoma
- (2012) Nai-Kong V. Cheung JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Clustered Mutations in Yeast and in Human Cancers Can Arise from Damaged Long Single-Strand DNA Regions
- (2012) Steven A. Roberts et al. MOLECULAR CELL
- A novel retinoblastoma therapy from genomic and epigenetic analyses
- (2012) Jinghui Zhang et al. NATURE
- Novel mutations target distinct subgroups of medulloblastoma
- (2012) Giles Robinson et al. NATURE
- Dissecting the genomic complexity underlying medulloblastoma
- (2012) David T. W. Jones et al. NATURE
- The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
- (2012) Jordi Barretina et al. NATURE
- The Pediatric Cancer Genome Project
- (2012) James R Downing et al. NATURE GENETICS
- Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
- (2012) Gang Wu et al. NATURE GENETICS
- RIM genes differentially contribute to organizing presynaptic release sites
- (2012) P. S. Kaeser et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Parent-specific copy number in paired tumor–normal studies using circular binary segmentation
- (2011) Adam B. Olshen et al. BIOINFORMATICS
- Challenging issues in pediatric oncology
- (2011) Ching-Hon Pui et al. Nature Reviews Clinical Oncology
- GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers
- (2011) Craig H Mermel et al. GENOME BIOLOGY
- Advances in the understanding of MYC-induced lymphomagenesis
- (2010) Kay Klapproth et al. BRITISH JOURNAL OF HAEMATOLOGY
- ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data
- (2010) K. Wang et al. NUCLEIC ACIDS RESEARCH
- Radio-induced malignancies after breast cancer post-operative radiotherapy in patients with Li- Fraumeni syndrome
- (2010) Steve Heymann et al. Radiation Oncology
- The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers
- (2009) S. Veeriah et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies
- (2009) Bryan N. Howie et al. PLoS Genetics
- The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15Ink4b
- (2008) Jin He et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
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