Mutational signature analysis identifies MUTYH deficiency in colorectal cancers and adrenocortical carcinomas

Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma

(2016) Siyuan Zheng et al.   CANCER CELL

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

(2016) Serena Nik-Zainal et al.   NATURE

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors

(2016) Jaegil Kim et al.   NATURE GENETICS

Adenoma development in familial adenomatous polyposis andMUTYH-associated polyposis: somatic landscape and driver genes

(2015) Mamunur Rashid et al.   JOURNAL OF PATHOLOGY

Telomerase activation by genomic rearrangements in high-risk neuroblastoma

(2015) Martin Peifer et al.   NATURE

Clock-like mutational processes in human somatic cells

(2015) Ludmil B Alexandrov et al.   NATURE GENETICS

Understanding the origins of human cancer

(2015) L. B. Alexandrov   SCIENCE

A mutational signature in gastric cancer suggests therapeutic strategies

(2015) Ludmil B. Alexandrov et al.   Nature Communications

Integrated genomic characterization of adrenocortical carcinoma

(2014) Guillaume Assié et al.   NATURE GENETICS

8-oxoguanine causes spontaneous de novo germline mutations in mice

(2014) Mizuki Ohno et al.   Scientific Reports

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Deciphering Signatures of Mutational Processes Operative in Human Cancer

(2013) Ludmil B. Alexandrov et al.   Cell Reports

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

(2012) Cécile Guichard et al.   NATURE GENETICS

Clinical Implications of the Colorectal Cancer Risk Associated With MUTYH Mutation

(2009) Steven J. Lubbe et al.   JOURNAL OF CLINICAL ONCOLOGY