C–C bond forming radical SAM enzymes involved in the construction of carbon skeletons of cofactors and natural products
出版年份 2018 全文链接
标题
C–C bond forming radical SAM enzymes involved in the construction of carbon skeletons of cofactors and natural products
作者
关键词
-
出版物
NATURAL PRODUCT REPORTS
Volume 35, Issue 7, Pages 660-694
出版商
Royal Society of Chemistry (RSC)
发表日期
2018-04-10
DOI
10.1039/c8np00006a
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- X-ray and EPR Characterization of the Auxiliary Fe–S Clusters in the Radical SAM Enzyme PqqE
- (2018) Ian Barr et al. BIOCHEMISTRY
- Substrate-Dependent Cleavage Site Selection by Unconventional Radical S-Adenosylmethionine Enzymes in Diphthamide Biosynthesis
- (2017) Min Dong et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- 7-Carboxy-7-deazaguanine Synthase: A Radical S-Adenosyl-l-methionine Enzyme with Polar Tendencies
- (2017) Nathan A. Bruender et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Aminofutalosine Synthase: Evidence for Captodative and Aryl Radical Intermediates Using β-Scission and SRN1 Trapping Reactions
- (2017) Sumedh Joshi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Reaction Catalyzed by GenK, a Cobalamin-Dependent Radical S-Adenosyl-l-methionine Methyltransferase in the Biosynthetic Pathway of Gentamicin, Proceeds with Retention of Configuration
- (2017) Hak Joong Kim et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A B12-dependent radical SAM enzyme involved in oxetanocin A biosynthesis
- (2017) Jennifer Bridwell-Rabb et al. NATURE
- Post-translational modification of ribosomally synthesized peptides by a radical SAM epimerase in Bacillus subtilis
- (2017) Alhosna Benjdia et al. Nature Chemistry
- Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition
- (2017) Katherine M. Davis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Construction of an octosyl acid backbone catalyzed by a radical S-adenosylmethionine enzyme and a phosphatase in the biosynthesis of high-carbon sugar nucleoside antibiotics
- (2017) Nisha He et al. Chemical Science
- Expanding Radical SAM Chemistry by Using Radical Addition Reactions and SAM Analogues
- (2016) Xinjian Ji et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Mechanistic Insights into the Radical S -adenosyl-l -methionine Enzyme NosL From a Substrate Analogue and the Shunt Products
- (2016) Xinjian Ji et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- RadicalS-Adenosylmethionine Enzymes in Human Health and Disease
- (2016) Bradley J. Landgraf et al. Annual Review of Biochemistry
- Biochemical and Spectroscopic Characterization of a Radical S-Adenosyl-l-methionine Enzyme Involved in the Formation of a Peptide Thioether Cross-Link
- (2016) Nathan A. Bruender et al. BIOCHEMISTRY
- Demonstration That the RadicalS-Adenosylmethionine (SAM) Enzyme PqqE Catalyzesde NovoCarbon-Carbon Cross-linking within a Peptide Substrate PqqA in the Presence of the Peptide Chaperone PqqD
- (2016) Ian Barr et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Organometallic Complex Formed by an Unconventional Radical S-Adenosylmethionine Enzyme
- (2016) Min Dong et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Carbon extension in peptidylnucleoside biosynthesis by radical SAM enzymes
- (2016) Edward A Lilla et al. Nature Chemical Biology
- An HD domain phosphohydrolase active site tailored for oxetanocin-A biosynthesis
- (2016) Jennifer Bridwell-Rabb et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Radical SAM catalysis via an organometallic intermediate with an Fe-[5'-C]-deoxyadenosyl bond
- (2016) M. Horitani et al. SCIENCE
- Fine-tuning of a radical-based reaction by radical S-adenosyl-L-methionine tryptophan lyase
- (2016) G. Sicoli et al. SCIENCE
- Substrate-Tuned Catalysis of the RadicalS-Adenosyl-L-Methionine Enzyme NosL Involved in Nosiheptide Biosynthesis
- (2015) Xinjian Ji et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Tryptophan Lyase (NosL): Mechanistic Insights from Substrate Analogues and Mutagenesis
- (2015) Dhananjay M. Bhandari et al. BIOCHEMISTRY
- PqqD Is a Novel Peptide Chaperone That Forms a Ternary Complex with the RadicalS-Adenosylmethionine Protein PqqE in the Pyrroloquinoline Quinone Biosynthetic Pathway
- (2015) John A. Latham et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- C-Terminal Glycine-Gated Radical Initiation by GTP 3′,8-Cyclase in the Molybdenum Cofactor Biosynthesis
- (2015) Bradley M. Hover et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Anaerobic 5-Hydroxybenzimidazole Formation from Aminoimidazole Ribotide: An Unanticipated Intersection of Thiamin and Vitamin B12 Biosynthesis
- (2015) Angad P. Mehta et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Biosynthetic Versatility and Coordinated Action of 5′-Deoxyadenosyl Radicals in Deazaflavin Biosynthesis
- (2015) Benjamin Philmus et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Electrochemical Resolution of the [4Fe-4S] Centers of the AdoMet Radical Enzyme BtrN: Evidence of Proton Coupling and an Unusual, Low-Potential Auxiliary Cluster
- (2015) Stephanie J. Maiocco et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A prevalent peptide-binding domain guides ribosomal natural product biosynthesis
- (2015) Brandon J Burkhart et al. Nature Chemical Biology
- Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslink
- (2015) Kelsey R. Schramma et al. Nature Chemistry
- Mechanism of pyranopterin ring formation in molybdenum cofactor biosynthesis
- (2015) Bradley M. Hover et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Anaerobic biosynthesis of the lower ligand of vitamin B12
- (2015) Amrita B. Hazra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Non-canonical active site architecture of the radical SAM thiamin pyrimidine synthase
- (2015) Michael K. Fenwick et al. Nature Communications
- Radical S-Adenosylmethionine Enzymes
- (2014) Joan B. Broderick et al. CHEMICAL REVIEWS
- SPASM and Twitch Domains inS-Adenosylmethionine (SAM) Radical Enzymes
- (2014) Tsehai A. J. Grell et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Modeling Nikkomycin Z Dosing and Pharmacology in Murine Pulmonary Coccidioidomycosis Preparatory to Phase 2 Clinical Trials
- (2014) L. F. Shubitz et al. JOURNAL OF INFECTIOUS DISEASES
- Characterization of a Radical S-Adenosyl-l-methionine Epimerase, NeoN, in the Last Step of Neomycin B Biosynthesis
- (2014) Fumitaka Kudo et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Dph3 Is an Electron Donor for Dph1-Dph2 in the First Step of Eukaryotic Diphthamide Biosynthesis
- (2014) Min Dong et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- In Vitro Reconstitution of the Radical S-Adenosylmethionine Enzyme MqnC Involved in the Biosynthesis of Futalosine-Derived Menaquinone
- (2013) Lisa E. Cooper et al. BIOCHEMISTRY
- Catalysis of a New Ribose Carbon-Insertion Reaction by the Molybdenum Cofactor Biosynthetic Enzyme MoaA
- (2013) Angad P. Mehta et al. BIOCHEMISTRY
- Flavodoxin cofactor binding induces structural changes that are required for protein–protein interactions with NADP+ oxidoreductase and pyruvate formate-lyase activating enzyme
- (2013) Adam V. Crain et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Molybdenum cofactor: A key component ofMycobacterium tuberculosispathogenesis?
- (2013) Monique Williams et al. CRITICAL REVIEWS IN MICROBIOLOGY
- The Thiamine Biosynthetic Enzyme ThiC Catalyzes Multiple Turnovers and Is Inhibited byS-Adenosylmethionine (AdoMet) Metabolites
- (2013) Lauren D. Palmer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Menaquinone Biosynthesis: Formation of Aminofutalosine Requires a Unique Radical SAM Enzyme
- (2013) Nilkamal Mahanta et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Identification of a Cyclic Nucleotide as a Cryptic Intermediate in Molybdenum Cofactor Biosynthesis
- (2013) Bradley M. Hover et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Two Fe-S clusters catalyze sulfur insertion by radical-SAM methylthiotransferases
- (2013) Farhad Forouhar et al. Nature Chemical Biology
- X-ray analysis of butirosin biosynthetic enzyme BtrN redefines structural motifs for AdoMet radical chemistry
- (2013) P. J. Goldman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of a small molecule with activity against drug-resistant and persistent tuberculosis
- (2013) F. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distribution and Properties of the Genes Encoding the Biosynthesis of the Bacterial Cofactor, Pyrroloquinoline Quinone
- (2012) Yao-Qing Shen et al. BIOCHEMISTRY
- Amalgamation of Nucleosides and Amino Acids in Antibiotic Biosynthesis: Discovery of an l-Threonine:Uridine-5′-Aldehyde Transaldolase
- (2012) Sandra Barnard-Britson et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Biosynthesis of F0, Precursor of the F420 Cofactor, Requires a Unique Two Radical-SAM Domain Enzyme and Tyrosine as Substrate
- (2012) Laure Decamps et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
- (2012) Paul G. Arnison et al. NATURAL PRODUCT REPORTS
- Biosynthesis of the tunicamycin antibiotics proceeds via unique exo-glycal intermediates
- (2012) Filip J. Wyszynski et al. Nature Chemistry
- Structural Insights into Radical Generation by the Radical SAM Superfamily
- (2011) Jessica L. Vey et al. CHEMICAL REVIEWS
- Molybdenum cofactor biosynthesis in plants and humans
- (2011) Ralf R. Mendel et al. COORDINATION CHEMISTRY REVIEWS
- Biological Systems Discovery In Silico: Radical S-Adenosylmethionine Protein Families and Their Target Peptides for Posttranslational Modification
- (2011) D. H. Haft et al. JOURNAL OF BACTERIOLOGY
- Characterization of LipL as a Non-heme, Fe(II)-dependent α-Ketoglutarate:UMP Dioxygenase That Generates Uridine-5′-aldehyde during A-90289 Biosynthesis
- (2011) Zhaoyong Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- 5′-Methylthioadenosine Nucleosidase Is Implicated in Playing a Key Role in a Modified Futalosine Pathway for Menaquinone Biosynthesis inCampylobacter jejuni
- (2011) Xu Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Convergent strategies in biosynthesis
- (2011) Tohru Dairi et al. NATURAL PRODUCT REPORTS
- Radical-mediated enzymatic carbon chain fragmentation-recombination
- (2011) Qi Zhang et al. Nature Chemical Biology
- Synthetic Lethal Compound Combinations Reveal a Fundamental Connection between Wall Teichoic Acid and Peptidoglycan Biosyntheses inStaphylococcus aureus
- (2010) Jennifer Campbell et al. ACS Chemical Biology
- Structures of apo and GTP-bound molybdenum cofactor biosynthesis protein MoaC fromThermus thermophilusHB8
- (2010) Shankar Prasad Kanaujia et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- A “Radical Dance” in Thiamin Biosynthesis: Mechanistic Analysis of the Bacterial Hydroxymethylpyrimidine Phosphate Synthase
- (2010) Abhishek Chatterjee et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- [FeFe]-Hydrogenase Cyanide Ligands Derived From S-Adenosylmethionine-Dependent Cleavage of Tyrosine
- (2010) Rebecca C. Driesener et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A Consensus Mechanism for Radical SAM-Dependent Dehydrogenation? BtrN Contains Two [4Fe-4S] Clusters
- (2010) Tyler L. Grove et al. BIOCHEMISTRY
- Regioselectivity in the Homolytic Cleavage of S-Adenosylmethionine
- (2010) Jack A. Kampmeier BIOCHEMISTRY
- Occurrence, biosynthesis and function of isoprenoid quinones
- (2010) Beatrycze Nowicka et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- The history of the discovery of the molybdenum cofactor and novel aspects of its biosynthesis in bacteria
- (2010) Silke Leimkühler et al. COORDINATION CHEMISTRY REVIEWS
- Diphthamide biosynthesis requires an organic radical generated by an iron–sulphur enzyme
- (2010) Yang Zhang et al. NATURE
- Characterization of the tunicamycin gene cluster unveiling unique steps involved in its biosynthesis
- (2010) Wenqing Chen et al. Protein & Cell
- Pyrroloquinoline Quinone Biogenesis: Demonstration That PqqE fromKlebsiella pneumoniaeIs a RadicalS-Adenosyl-l-methionine Enzyme
- (2009) Stephen R. Wecksler et al. BIOCHEMISTRY
- Anaerobic functionalization of unactivated C–H bonds
- (2009) Squire J Booker CURRENT OPINION IN CHEMICAL BIOLOGY
- Characterization of the Polyoxin Biosynthetic Gene Cluster fromStreptomyces cacaoiand Engineered Production of Polyoxin H
- (2009) Wenqing Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Catalytic Activity of the Anaerobic Tyrosine Lyase Required for Thiamine Biosynthesis in Escherichia coli
- (2009) Martin R. Challand et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pyrroloquinoline Quinone Stimulates Mitochondrial Biogenesis through cAMP Response Element-binding Protein Phosphorylation and Increased PGC-1α Expression
- (2009) Winyoo Chowanadisai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ENDOR Spectroscopy Shows That Guanine N1 Binds to [4Fe−4S] Cluster II of theS-Adenosylmethionine-Dependent Enzyme MoaA: Mechanistic Implications
- (2009) Nicholas S. Lees et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds
- (2009) John A. McIntosh et al. NATURAL PRODUCT REPORTS
- Antimicrobial nucleoside antibiotics targeting cell wall assembly: Recent advances in structure–function studies and nucleoside biosynthesis
- (2009) Michael Winn et al. NATURAL PRODUCT REPORTS
- Molybdenum cofactors, enzymes and pathways
- (2009) Günter Schwarz et al. NATURE
- Unexpected electron transfer mechanism upon AdoMet cleavage in radical SAM proteins
- (2009) Y. Nicolet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The archaeal cofactor F0is a light-harvesting antenna chromophore in eukaryotes
- (2009) Andreas F. Glas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Conversion of NO2 to NO by reduced coenzyme F420 protects mycobacteria from nitrosative damage
- (2009) E. Purwantini et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanistic Study on the Reaction of a Radical SAM Dehydrogenase BtrN by Electron Paramagnetic Resonance Spectroscopy†
- (2008) Kenichi Yokoyama et al. BIOCHEMISTRY
- ThiC Is an [Fe-S] Cluster Protein That Requires AdoMet To Generate the 4-Amino-5-hydroxymethyl-2-methylpyrimidine Moiety in Thiamin Synthesis†
- (2008) N. Cecilia Martinez-Gomez et al. BIOCHEMISTRY
- Reaction of AdoMet with ThiC Generates a Backbone Free Radical†
- (2008) N. Cecilia Martinez-Gomez et al. BIOCHEMISTRY
- DNA Repair and Free Radicals, New Insights into the Mechanism of Spore Photoproduct Lyase Revealed by Single Amino Acid Substitution
- (2008) Alexia Chandor-Proust et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Studies on A New Biosynthetic Pathway for Menaquinone
- (2008) Haruo Seto et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
- (2008) Abhishek Chatterjee et al. Nature Chemical Biology
- Structural basis for glycyl radical formation by pyruvate formate-lyase activating enzyme
- (2008) J. L. Vey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Alternative Menaquinone Biosynthetic Pathway Operating in Microorganisms
- (2008) T. Hiratsuka et al. SCIENCE
- PA-824 Kills Nonreplicating Mycobacterium tuberculosis by Intracellular NO Release
- (2008) R. Singh et al. SCIENCE
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