A multi-omic study reveals BTG2 as a reliable prognostic marker for early-stage non-small cell lung cancer

Lung cancer: current therapies and new targeted treatments

(2017) Fred R Hirsch et al.   LANCET

Seven-CpG-based prognostic signature coupled with gene expression predicts survival of oral squamous cell carcinoma

(2017) Sipeng Shen et al.   Clinical Epigenetics

Development and Validation of an Individualized Immune Prognostic Signature in Early-Stage Nonsquamous Non–Small Cell Lung Cancer

(2017) Bailiang Li et al.   JAMA Oncology

ITPKA Gene Body Methylation Regulates Gene Expression and Serves as an Early Diagnostic Marker in Lung and Other Cancers

(2016) Yi-Wei Wang et al.   Journal of Thoracic Oncology

Quantitative comparison of DNA methylation assays for biomarker development and clinical applications

(2016) Christoph Bock et al.   NATURE BIOTECHNOLOGY

Targeting the cancer epigenome for therapy

(2016) Peter A. Jones et al.   NATURE REVIEWS GENETICS

BTG2 bridges PABPC1 RNA-binding domains and CAF1 deadenylase to control cell proliferation

(2016) Benjamin Stupfler et al.   Nature Communications

Prognostic and Predictive Value inKRASin Non–Small-Cell Lung Cancer

(2016) Kevin Wood et al.   JAMA Oncology

miR-25 modulates NSCLC cell radio-sensitivity through directly inhibiting BTG2 expression

(2015) Zhiwei He et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hypoxia-induced p53 modulates both apoptosis and radiosensitivity via AKT

(2015) Katarzyna B. Leszczynska et al.   JOURNAL OF CLINICAL INVESTIGATION

An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma Based on mRNA, microRNA, and DNA Methylation Biomarkers

(2015) Ana I. Robles et al.   Journal of Thoracic Oncology

Genome-wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis

(2015) Maria Moksnes Bjaanaes et al.   Molecular Oncology

Gene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer

(2014) Xiaojing Yang et al.   CANCER CELL

Genome-wide DNA Methylation Analysis of Lung Carcinoma Reveals One Neuroendocrine and Four Adenocarcinoma Epitypes Associated with Patient Outcome

(2014) A. Karlsson et al.   CLINICAL CANCER RESEARCH

Comparing two correlated C indices with right-censored survival outcome: a one-shot nonparametric approach

(2014) Le Kang et al.   STATISTICS IN MEDICINE

Endogenous BTG2 expression stimulates migration of bladder cancer cells and correlates with poor clinical prognosis for bladder cancer patients

(2013) N Wagener et al.   BRITISH JOURNAL OF CANCER

Regulation of Btg2/TIS21/PC3 expression via reactive oxygen species–protein kinase C–ΝFκΒ pathway under stress conditions

(2013) Muhammad Imran et al.   CELLULAR SIGNALLING

TIS21/BTG2/PC3 inhibits interleukin-6 expression via downregulation of STAT3 pathway

(2013) Linh Nguyen Quy et al.   CELLULAR SIGNALLING

MicroRNAs Cooperatively Inhibit a Network of Tumor Suppressor Genes to Promote Pancreatic Tumor Growth and Progression

(2013) Adam E. Frampton et al.   GASTROENTEROLOGY

A Prognostic DNA Methylation Signature for Stage I Non–Small-Cell Lung Cancer

(2013) Juan Sandoval et al.   JOURNAL OF CLINICAL ONCOLOGY

Validation of a Histology-Independent Prognostic Gene Signature for Early-Stage, Non–Small-Cell Lung Cancer Including Stage IA Patients

(2013) Sandy D. Der et al.   Journal of Thoracic Oncology

BTG2 Overexpression Increases the Radiosensitivity of Breast Cancer Cells In Vitro and In Vivo

(2013) Xudong Hu et al.   ONCOLOGY RESEARCH

Expression and significance of miRNA-21 and BTG2 in lung cancer

(2013) Qing Sun et al.   TUMOR BIOLOGY

BTG2 inhibits the proliferation, invasion, and apoptosis of MDA-MB-231 triple-negative breast cancer cells

(2013) Yan-jun Zhang et al.   TUMOR BIOLOGY

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

BTG2 loss and miR-21 upregulation contribute to prostate cell transformation by inducing luminal markers expression and epithelial–mesenchymal transition

(2012) V Coppola et al.   ONCOGENE

Effects of BTG2 on proliferation inhibition and anti-invasion in human lung cancer cells

(2012) Sen Wei et al.   TUMOR BIOLOGY

A 5-MicroRNA Signature for Lung Squamous Cell Carcinoma Diagnosis and hsa-miR-31 for Prognosis

(2011) X. Tan et al.   CLINICAL CANCER RESEARCH

Breast tumor progression induced by loss of BTG2 expression is inhibited by targeted therapy with the ErbB/HER inhibitor lapatinib

(2011) F Takahashi et al.   ONCOGENE

MicroRNA Classifiers for Predicting Prognosis of Squamous Cell Lung Cancer

(2009) M. Raponi et al.   CANCER RESEARCH

Regulation of the cell cycle gene, BTG2, by miR-21 in human laryngeal carcinoma

(2009) Min Liu et al.   CELL RESEARCH

Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

(2009) Madeleine P Ball et al.   NATURE BIOTECHNOLOGY

Gene expression–based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study

(2008) Kerby Shedden et al.   NATURE MEDICINE