SOCS1-targeted therapy ameliorates renal and vascular oxidative stress in diabetes via STAT1 and PI3K inhibition
出版年份 2018 全文链接
标题
SOCS1-targeted therapy ameliorates renal and vascular oxidative stress in diabetes via STAT1 and PI3K inhibition
作者
关键词
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出版物
LABORATORY INVESTIGATION
Volume -, Issue -, Pages -
出版商
Springer Nature
发表日期
2018-03-15
DOI
10.1038/s41374-018-0043-6
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Suppressor of Cytokine Signaling-1 Peptidomimetic Limits Progression of Diabetic Nephropathy
- (2016) Carlota Recio et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Hepatic Deletion of Janus Kinase 2 Counteracts Oxidative Stress in Mice
- (2016) Madeleine Themanns et al. Scientific Reports
- Gene delivery of suppressors of cytokine signaling (SOCS) inhibits inflammation and atherosclerosis development in mice
- (2015) Carlota Recio et al. BASIC RESEARCH IN CARDIOLOGY
- JAK inhibition and progressive kidney disease
- (2015) Frank C. Brosius et al. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
- NADPH oxidase NOX1 is involved in activation of protein kinase C and premature senescence in early stage diabetic kidney
- (2015) Kai Zhu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Gene therapy with neurogenin3, betacellulin and SOCS1 reverses diabetes in NOD mice
- (2015) R Li et al. GENE THERAPY
- Regulation of Nox enzymes expression in vascular pathophysiology: Focusing on transcription factors and epigenetic mechanisms
- (2015) Simona-Adriana Manea et al. Redox Biology
- Suppressor of Cytokine Signaling 1–Derived Peptide Inhibits Janus Kinase/Signal Transducers and Activators of Transcription Pathway and Improves Inflammation and Atherosclerosis in Diabetic Mice
- (2014) Carlota Recio et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Nox family NADPH oxidases: Molecular mechanisms of activation
- (2014) Ralf P. Brandes et al. FREE RADICAL BIOLOGY AND MEDICINE
- Genetic Targeting or Pharmacologic Inhibition of NADPH Oxidase Nox4 Provides Renoprotection in Long-Term Diabetic Nephropathy
- (2014) J. C. Jha et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Therapeutic approaches to diabetic nephropathy—beyond the RAS
- (2014) Beatriz Fernandez-Fernandez et al. Nature Reviews Nephrology
- Vascular Complications of Diabetes: Mechanisms of Injury and Protective Factors
- (2013) Christian Rask-Madsen et al. Cell Metabolism
- NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis
- (2013) Stephen P. Gray et al. CIRCULATION
- Nox as a target for diabetic complications
- (2013) Yves Gorin et al. CLINICAL SCIENCE
- Suppression of cytokine signaling: The SOCS perspective
- (2013) Edmond M. Linossi et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Therapeutic Effects of Suppressors of Cytokine Signaling in Diabetic Nephropathy
- (2013) Qingjuan Liu et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Diabetic nephropathy: diagnosis and treatment
- (2013) Daniel Fineberg et al. Nature Reviews Endocrinology
- Gene Deficiency in Activating Fcγ Receptors Influences the Macrophage Phenotypic Balance and Reduces Atherosclerosis in Mice
- (2013) Beñat Mallavia et al. PLoS One
- Heme Oxygenase-1 Prevents Cardiac Dysfunction in Streptozotocin-Diabetic Mice by Reducing Inflammation, Oxidative Stress, Apoptosis and Enhancing Autophagy
- (2013) Yanli Zhao et al. PLoS One
- Catalase Deficiency Accelerates Diabetic Renal Injury Through Peroxisomal Dysfunction
- (2012) I. Hwang et al. DIABETES
- The JAK-STAT Pathway at Twenty
- (2012) George R. Stark et al. IMMUNITY
- SOD1, but not SOD3, deficiency accelerates diabetic renal injury in C57BL/6-Ins2Akita diabetic mice
- (2012) Hiroki Fujita et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Role of Suppressor of Cytokine Signaling-1 In Murine Atherosclerosis
- (2012) Christina Grothusen et al. PLoS One
- Oxidative Stress, Nox Isoforms and Complications of Diabetes—Potential Targets for Novel Therapies
- (2012) Mona Sedeek et al. Journal of Cardiovascular Translational Research
- Tyrphostin AG490 reduces NAPDH oxidase activity and expression in the aorta of hypercholesterolemic apolipoprotein E-deficient mice
- (2011) Ioana M. Fenyo et al. VASCULAR PHARMACOLOGY
- Oxidative Stress in Diabetic Nephropathy
- (2010) N. Kashihara et al. CURRENT MEDICINAL CHEMISTRY
- Suppressors of Cytokine Signaling Abrogate Diabetic Nephropathy
- (2010) G. Ortiz-Munoz et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Suppressors of Cytokine Signaling Modulate JAK/STAT-Mediated Cell Responses During Atherosclerosis
- (2009) Guadalupe Ortiz-Muñoz et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- JAK/STAT Signaling Pathway Regulates Nox1 and Nox4-Based NADPH Oxidase in Human Aortic Smooth Muscle Cells
- (2009) Adrian Manea et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Poldip2, a Novel Regulator of Nox4 and Cytoskeletal Integrity in Vascular Smooth Muscle Cells
- (2009) Alicia N. Lyle et al. CIRCULATION RESEARCH
- SOCS1 protects protein tyrosine phosphatases by thioredoxin upregulation and attenuates Jaks to suppress ROS-mediated apoptosis
- (2009) J Oh et al. ONCOGENE
- Redox Regulation of Cell Survival
- (2008) Dunyaporn Trachootham et al. ANTIOXIDANTS & REDOX SIGNALING
- Inflammation and immunity in diabetic vascular complications
- (2008) Jan Nilsson et al. CURRENT OPINION IN LIPIDOLOGY
- Increased expression of SOCS3 in monocytes and SOCS1 in lymphocytes correlates with progressive loss of renal function and cardiovascular risk factors in chronic kidney disease
- (2008) M. Mehdi Rastmanesh et al. EUROPEAN JOURNAL OF PHARMACOLOGY
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