The Amino Terminus of Herpes Simplex Virus 1 Glycoprotein K (gK) Is Required for gB Binding to Akt, Release of Intracellular Calcium, and Fusion of the Viral Envelope with Plasma Membranes

Cysteines and N-Glycosylation Sites Conserved among All Alphaherpesviruses Regulate Membrane Fusion in Herpes Simplex Virus 1 Infection

(2017) Paul J. F. Rider et al.   JOURNAL OF VIROLOGY

Vaccination of rhesus macaques with the live-attenuated HSV-1 vaccine VC2 stimulates the proliferation of mucosal T cells and germinal center responses resulting in sustained production of highly neutralizing antibodies

(2017) Brent A. Stanfield et al.   VACCINE

Herpesvirus Entry into Host Cells Mediated by Endosomal Low pH

(2016) Anthony V. Nicola   TRAFFIC

Deletion of a Predicted β-Sheet Domain within the Amino Terminus of Herpes Simplex Virus Glycoprotein K Conserved among Alphaherpesviruses Prevents Virus Entry into Neuronal Axons

(2015) Nithya Jambunathan et al.   JOURNAL OF VIROLOGY

Membrane Perturbation-Associated Ca2+Signaling and Incoming Genome Sensing Are Required for the Host Response to Low-Level Enveloped Virus Particle Entry

(2015) David N. Hare et al.   JOURNAL OF VIROLOGY

The role of PI3K/Akt in human herpesvirus infection: From the bench to the bedside

(2015) XueQiao Liu et al.   VIROLOGY

Binding of Alphaherpesvirus Glycoprotein H to Surface α 4 β 1 -Integrins Activates Calcium-Signaling Pathways and Induces Phosphatidylserine Exposure on the Plasma Membrane

(2015) Walid Azab et al.   mBio

A Replication Competent HSV-1(McKrae) with a Mutation in the Amino-terminus of Glycoprotein K (gK) is Unable to Infect Mouse Trigeminal Ganglia after Cornea Infection

(2014) Ahmad A. Saied et al.   CURRENT EYE RESEARCH

Herpes Simplex Virus 1 Protein UL37 Interacts with Viral Glycoprotein gK and Membrane Protein UL20 and Functions in Cytoplasmic Virion Envelopment

(2014) N. Jambunathan et al.   JOURNAL OF VIROLOGY

A Single Intramuscular Vaccination of Mice with the HSV-1 VC2 Virus with Mutations in the Glycoprotein K and the Membrane Protein UL20 Confers Full Protection against Lethal Intravaginal Challenge with Virulent HSV-1 and HSV-2 Strains

(2014) Brent A. Stanfield et al.   PLoS One

HSV activates Akt to trigger calcium release and promote viral entry: novel candidate target for treatment and suppression

(2013) Natalia Cheshenko et al.   FASEB JOURNAL

The Amino Terminus of Herpes Simplex Virus 1 Glycoprotein K Is Required for Virion Entry via the Paired Immunoglobulin-Like Type-2 Receptor Alpha

(2013) S. Chowdhury et al.   JOURNAL OF VIROLOGY

Ultrastructural Visualization of Individual Tegument Protein Dissociation during Entry of Herpes Simplex Virus 1 into Human and Rat Dorsal Root Ganglion Neurons

(2012) A. Aggarwal et al.   JOURNAL OF VIROLOGY

Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING

(2012) Christian K Holm et al.   NATURE IMMUNOLOGY

Pitstop 2 Is a Potent Inhibitor of Clathrin-Independent Endocytosis

(2012) Dipannita Dutta et al.   PLoS One

Herpes Virus Fusion and Entry: A Story with Many Characters

(2012) Roselyn J. Eisenberg et al.   Viruses-Basel

A Herpes Simplex Virus 1 (McKrae) Mutant Lacking the Glycoprotein K Gene Is Unable To Infect via Neuronal Axons and Egress from Neuronal Cell Bodies

(2012) A. T. David et al.   mBio

PI3K-PKB/Akt Pathway

(2012) B. A. Hemmings et al.   Cold Spring Harbor Perspectives in Biology

Viral and cellular contributions to herpes simplex virus entry into the cell

(2012) Gabriella Campadelli-Fiume et al.   Current Opinion in Virology

Akt signalling in health and disease

(2011) Ingeborg Hers et al.   CELLULAR SIGNALLING

Site-Specific Proteolytic Cleavage of the Amino Terminus of Herpes Simplex Virus Glycoprotein K on Virion Particles Inhibits Virus Entry

(2011) N. Jambunathan et al.   JOURNAL OF VIROLOGY

Fusing structure and function: a structural view of the herpesvirus entry machinery

(2011) Sarah A. Connolly et al.   NATURE REVIEWS MICROBIOLOGY

Entry Pathways of Herpes Simplex Virus Type 1 into Human Keratinocytes Are Dynamin- and Cholesterol-Dependent

(2011) Elena Rahn et al.   PLoS One

Herpes Simplex Virus is Akt-ing in translational control

(2010) K. L. Norman et al.   GENES & DEVELOPMENT

The Herpes Simplex Virus Type 1 UL20 Protein and the Amino Terminus of Glycoprotein K (gK) Physically Interact with gB

(2010) V. N. Chouljenko et al.   JOURNAL OF VIROLOGY

Cascade of Events Governing Cell-Cell Fusion Induced by Herpes Simplex Virus Glycoproteins gD, gH/gL, and gB

(2010) D. Atanasiu et al.   JOURNAL OF VIROLOGY

Non-muscle myosin IIA is a functional entry receptor for herpes simplex virus-1

(2010) Jun Arii et al.   NATURE

Binding of Herpes Simplex Virus Type-1 Virions Leads to the Induction of Intracellular Signalling in the Absence of Virus Entry

(2010) Iain J. MacLeod et al.   PLoS One

The Herpes Simplex Virus Type 1 (HSV-1) Glycoprotein K(gK) is Essential for Viral Corneal Spread and Neuroinvasiveness

(2009) Andrew T. David et al.   CURRENT EYE RESEARCH

The Amino Terminus of Herpes Simplex Virus Type 1 Glycoprotein K (gK) Modulates gB-Mediated Virus-Induced Cell Fusion and Virion Egress

(2009) V. N. Chouljenko et al.   JOURNAL OF VIROLOGY

Myelin-associated glycoprotein mediates membrane fusion and entry of neurotropic herpesviruses

(2009) T. Suenaga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PILRα Is a Herpes Simplex Virus-1 Entry Coreceptor That Associates with Glycoprotein B

(2008) Takeshi Satoh et al.   CELL

Functional and Physical Interactions of the Herpes Simplex Virus Type 1 UL20 Membrane Protein with Glycoprotein K

(2008) T. P. Foster et al.   JOURNAL OF VIROLOGY

Native 3D intermediates of membrane fusion in herpes simplex virus 1 entry

(2008) U. E. Maurer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy

(2008) Pauline Chugh et al.   Retrovirology