Decreased microglial activation through gut-brain axis by prebiotics, probiotics, or synbiotics effectively restored cognitive function in obese-insulin resistant rats

The Crosstalk between the Gut Microbiota and Mitochondria during Exercise

(2017) Allison Clark et al.   Frontiers in Physiology

Impact of the gut microbiota on rodent models of human disease

(2017) Axel Kornerup Hansen et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Dietary obesity reversibly induces synaptic stripping by microglia and impairs hippocampal plasticity

(2016) Shuai Hao et al.   BRAIN BEHAVIOR AND IMMUNITY

Prebiotics effect on immune and hepatic oxidative status and gut morphology of white sea bream (Diplodus sargus)

(2016) Inês Guerreiro et al.   FISH & SHELLFISH IMMUNOLOGY

FGF21 improves cognition by restored synaptic plasticity, dendritic spine density, brain mitochondrial function and cell apoptosis in obese-insulin resistant male rats

(2016) Piangkwan Sa-nguanmoo et al.   HORMONES AND BEHAVIOR

Blood–brain barrier breakdown promotes macrophage infiltration and cognitive impairment in leptin receptor-deficient mice

(2016) Alexis M Stranahan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants

(2016)   LANCET

Testosterone deprivation has neither additive nor synergistic effects with obesity on the cognitive impairment in orchiectomized and/or obese male rats

(2016) Hiranya Pintana et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome

(2016) Rachel J. Perry et al.   NATURE

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

Vagus Nerve Stimulation Exerts the Neuroprotective Effects in Obese-Insulin Resistant Rats, Leading to the Improvement of Cognitive Function

(2016) Titikorn Chunchai et al.   Scientific Reports

Testosterone replacement attenuates cognitive decline in testosterone-deprived lean rats, but not in obese rats, by mitigating brain oxidative stress

(2015) Hiranya Pintana et al.   AGE

Bifidobacteria modulate cognitive processes in an anxious mouse strain

(2015) H.M. Savignac et al.   BEHAVIOURAL BRAIN RESEARCH

Obesity accelerates cognitive decline by aggravating mitochondrial dysfunction, insulin resistance and synaptic dysfunction under estrogen-deprived conditions

(2015) Wasana Pratchayasakul et al.   HORMONES AND BEHAVIOR

In vitrostudy of the prebiotic xylooligosaccharide (XOS) on the growth ofBifidobacteriumspp andLactobacillusspp

(2015) Zhaoping Li et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Dipeptidyl peptidase 4 inhibitor improves brain insulin sensitivity, but fails to prevent cognitive impairment in orchiectomy obese rats

(2015) Hiranya Pintana et al.   JOURNAL OF ENDOCRINOLOGY

High-fat Diet-induced Intestinal Hyperpermeability is Associated with Increased Bile Acids in the Large Intestine of Mice

(2015) Yuki Murakami et al.   JOURNAL OF FOOD SCIENCE

Prebiotic Potential of Xylooligosaccharides Derived from Corn Cobs and Their In Vitro Antioxidant Activity When Combined with Lactobacillus

(2015) Xiuhua Yu et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Microbiota and neuroimmune signalling—Metchnikoff to microglia

(2015) John F. Cryan et al.   Nature Reviews Gastroenterology & Hepatology

Mitochondrial ROS govern the LPS-induced pro-inflammatory response in microglia cells by regulating MAPK and NF-κB pathways

(2015) Junghyung Park et al.   NEUROSCIENCE LETTERS

Microbiota–mitochondria inter-talk: consequence for microbiota–host interaction

(2015) Yann Saint-Georges-Chaumet et al.   Pathogens and Disease

Garlic extract attenuates brain mitochondrial dysfunction and cognitive deficit in obese-insulin resistant rats

(2014) Hiranya Pintana et al.   Applied Physiology Nutrition and Metabolism

DPP-4 Inhibitor and PPARγ Agonist Restore the Loss of CA1 Dendritic Spines in Obese Insulin-resistant Rats

(2014) Jirapas Sripetchwandee et al.   ARCHIVES OF MEDICAL RESEARCH

Modulation of gut microbiota during probiotic-mediated attenuation of metabolic syndrome in high fat diet-fed mice

(2014) Jingjing Wang et al.   ISME Journal

Obesity Elicits Interleukin 1-Mediated Deficits in Hippocampal Synaptic Plasticity

(2014) J. R. Erion et al.   JOURNAL OF NEUROSCIENCE

Ingestion of Lactobacillus strain reduces anxiety and improves cognitive function in the hyperammonemia rat

(2014) Jia Luo et al.   Science China-Life Sciences

Effect of Lactobacillus rhamnosus CGMCC1.3724 supplementation on weight loss and maintenance in obese men and women

(2013) Marina Sanchez et al.   BRITISH JOURNAL OF NUTRITION

Exploring host-microbiota interactions in animal models and humans

(2013) A. D. Kostic et al.   GENES & DEVELOPMENT

DPP-4 inhibitors improve cognition and brain mitochondrial function of insulin-resistant rats

(2013) Hiranya Pintana et al.   JOURNAL OF ENDOCRINOLOGY

Dietary Xylooligosaccharide Downregulates IFN-γ and the Low-Grade Inflammatory Cytokine IL-1β Systemically in Mice

(2013) Camilla H. F. Hansen et al.   JOURNAL OF NUTRITION

Microglia: New Roles for the Synaptic Stripper

(2013) Helmut Kettenmann et al.   NEURON

Damaging effects of a high-fat diet to the brain and cognition: A review of proposed mechanisms

(2013) Linnea R. Freeman et al.   NUTRITIONAL NEUROSCIENCE

Probiotics, Prebiotics and Immunomodulation of Gut Mucosal Defences: Homeostasis and Immunopathology

(2013) Holly Hardy et al.   Nutrients

Fiber and Prebiotics: Mechanisms and Health Benefits

(2013) Joanne Slavin   Nutrients

DPP4-inhibitor improves neuronal insulin receptor function, brain mitochondrial function and cognitive function in rats with insulin resistance induced by high-fat diet consumption

(2012) Noppamas Pipatpiboon et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Effects of metformin on learning and memory behaviors and brain mitochondrial functions in high fat diet induced insulin resistant rats

(2012) Hiranya Pintana et al.   LIFE SCIENCES

Comparative meta-analysis of the effect of Lactobacillus species on weight gain in humans and animals

(2012) Matthieu Million et al.   MICROBIAL PATHOGENESIS

The gut microbiota, obesity and insulin resistance

(2012) Jian Shen et al.   MOLECULAR ASPECTS OF MEDICINE

PPARγ Agonist Improves Neuronal Insulin Receptor Function in Hippocampus and Brain Mitochondria Function in Rats with Insulin Resistance Induced by Long Term High-Fat Diets

(2011) Noppamas Pipatpiboon et al.   ENDOCRINOLOGY

A novel cystine based antioxidant attenuates oxidative stress and hepatic steatosis in diet-induced obese mice

(2011) Indrani Sinha-Hikim et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Effects of high-fat diet on insulin receptor function in rat hippocampus and the level of neuronal corticosterone

(2011) Wasana Pratchayasakul et al.   LIFE SCIENCES

The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication

(2011) P. Bercik et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Consumption of a high-fat diet induces central insulin resistance independent of adiposity

(2011) Deborah J. Clegg et al.   PHYSIOLOGY & BEHAVIOR

Reactive Oxygen Species in the Regulation of Synaptic Plasticity and Memory

(2010) Cynthia A. Massaad et al.   ANTIOXIDANTS & REDOX SIGNALING

Gut inflammation provides a respiratory electron acceptor for Salmonella

(2010) Sebastian E. Winter et al.   NATURE

Xylo-oligosaccharides and lactitol promote the growth of Bifidobacterium lactis and Lactobacillus species in pure cultures

(2010) H. Mäkeläinen et al.   Beneficial Microbes

Proinflammatory Cytokines Activate the Intrinsic Apoptotic Pathway in  -Cells

(2009) L. G. Grunnet et al.   DIABETES

Involvement of Reactive Oxygen Species in Long-Term Potentiation in the Spinal Cord Dorsal Horn

(2009) Kwan Yeop Lee et al.   JOURNAL OF NEUROPHYSIOLOGY

Probiotics: Definition, Sources, Selection, and Uses

(2008) Mary Ellen Sanders   CLINICAL INFECTIOUS DISEASES

Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats

(2008) Alexis M. Stranahan et al.   HIPPOCAMPUS

Role of gut microflora in the development of obesity and insulin resistance following high-fat diet feeding

(2008) P.D. Cani et al.   PATHOLOGIE BIOLOGIE