Unveiling anti-oxidative and anti-inflammatory effects of docosahexaenoic acid and its lipid peroxidation product on lipopolysaccharide-stimulated BV-2 microglial cells
出版年份 2018 全文链接
标题
Unveiling anti-oxidative and anti-inflammatory effects of docosahexaenoic acid and its lipid peroxidation product on lipopolysaccharide-stimulated BV-2 microglial cells
作者
关键词
Docosahexaenoic acid (DHA), 4-Hydroxyhexenal (4-HHE), 4-Hydroxynonenal (4-HNE), Microglia, Lipopolysaccharide (LPS), NO, ROS, Nrf2, HO-1, cPLA<sub>2</sub>, iPLA<sub>2</sub>
出版物
Journal of Neuroinflammation
Volume 15, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-07-09
DOI
10.1186/s12974-018-1232-3
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Antioxidants and HNE in redox homeostasis
- (2017) Wojciech Łuczaj et al. FREE RADICAL BIOLOGY AND MEDICINE
- Chemistry and analysis of HNE and other prominent carbonyl-containing lipid oxidation compounds
- (2017) Bebiana C. Sousa et al. FREE RADICAL BIOLOGY AND MEDICINE
- Docosahexaenoic acid-containing choline phospholipid modulates LPS-induced neuroinflammation in vivo and in microglia in vitro
- (2017) Célia Fourrier et al. Journal of Neuroinflammation
- Docosahexaenoic acid (DHA): An essential nutrient and a nutraceutical for brain health and diseases
- (2017) Grace Y. Sun et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- Natural Docosahexaenoic Acid in the Triglyceride Form Attenuates In Vitro Microglial Activation and Ameliorates Autoimmune Encephalomyelitis in Mice
- (2017) Pilar Mancera et al. Nutrients
- Derivatization Strategy for the Comprehensive Characterization of Endogenous Fatty Aldehydes Using HPLC-Multiple Reaction Monitoring
- (2016) Cai Tie et al. ANALYTICAL CHEMISTRY
- N-3 polyunsaturated fatty acids in animal models with neuroinflammation: An update
- (2016) Marc-Olivier Trépanier et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Lipid peroxidation in the pathogenesis of neuroborreliosis
- (2016) Anna Moniuszko-Malinowska et al. FREE RADICAL BIOLOGY AND MEDICINE
- Remodeling of lipid bodies by docosahexaenoic acid in activated microglial cells
- (2016) Marie-Eve Tremblay et al. Journal of Neuroinflammation
- Hormetic and regulatory effects of lipid peroxidation mediators in pancreatic beta cells
- (2016) Giuseppe Maulucci et al. MOLECULAR ASPECTS OF MEDICINE
- Botanical Polyphenols Mitigate Microglial Activation and Microglia-Induced Neurotoxicity: Role of Cytosolic Phospholipase A2
- (2016) Dennis Y. Chuang et al. NEUROMOLECULAR MEDICINE
- On the role of 4-hydroxynonenal in health and disease
- (2015) Miklós Csala et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- A validated LC-MS/MS assay for quantification of 24(S)-hydroxycholesterol in plasma and cerebrospinal fluid
- (2015) Rohini Sidhu et al. JOURNAL OF LIPID RESEARCH
- Calcium-independent phospholipases A2and their roles in biological processes and diseases
- (2015) Sasanka Ramanadham et al. JOURNAL OF LIPID RESEARCH
- Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway
- (2015) Dennis Y. Chuang et al. Journal of Neuroinflammation
- Quercetin Attenuates Inflammatory Responses in BV-2 Microglial Cells: Role of MAPKs on the Nrf2 Pathway and Induction of Heme Oxygenase-1
- (2015) Grace Y. Sun et al. PLoS One
- The benefit of docosahexaenoic acid for the adult brain in aging and dementia
- (2015) Norman Salem et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- Tick-borne encephalitis – lipid peroxidation and its consequences
- (2015) Wojciech Łuczaj et al. SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION
- Duality of n-3 Polyunsaturated Fatty Acids on Mcp-1 Expression in Vascular Smooth Muscle: A Potential Role of 4-Hydroxy Hexenal
- (2015) Kohji Nagayama et al. Nutrients
- Endogenous Generation and Signaling Actions of Omega-3 Fatty Acid Electrophilic Derivatives
- (2015) Chiara Cipollina Biomed Research International
- Docosahexaenoic acid attenuates the early inflammatory response following spinal cord injury in mice: in-vivo and in-vitro studies
- (2014) Irene Paterniti et al. Journal of Neuroinflammation
- Omega-3 Fatty Acids Protect the Brain against Ischemic Injury by Activating Nrf2 and Upregulating Heme Oxygenase 1
- (2014) M. Zhang et al. JOURNAL OF NEUROSCIENCE
- Cellular Membrane Fluidity in Amyloid Precursor Protein Processing
- (2014) Xiaoguang Yang et al. MOLECULAR NEUROBIOLOGY
- Role of Cytosolic Phospholipase A2 in Oxidative and Inflammatory Signaling Pathways in Different Cell Types in the Central Nervous System
- (2014) Grace Y. Sun et al. MOLECULAR NEUROBIOLOGY
- Role of Omega-3 Fatty Acids in the Treatment of Depressive Disorders: A Comprehensive Meta-Analysis of Randomized Clinical Trials
- (2014) Giuseppe Grosso et al. PLoS One
- Omega-3 fatty acids and brain resistance to ageing and stress: Body of evidence and possible mechanisms
- (2013) I. Denis et al. AGEING RESEARCH REVIEWS
- 4-Hydroxy hexenal derived from dietary n-3 polyunsaturated fatty acids induces anti-oxidative enzyme heme oxygenase-1 in multiple organs
- (2013) Fumiyuki Nakagawa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Magnolia polyphenols attenuate oxidative and inflammatory responses in neurons and microglial cells
- (2013) Dennis Y Chuang et al. Journal of Neuroinflammation
- 4-Hydroxy Hexenal Derived from Docosahexaenoic Acid Protects Endothelial Cells via Nrf2 Activation
- (2013) Atsushi Ishikado et al. PLoS One
- Omega-3 fatty acids and traumatic neurological injury: from neuroprotection to neuroplasticity?
- (2013) Adina T. Michael-Titus et al. TRENDS IN NEUROSCIENCES
- Shotgun Lipidomics Analysis of 4-Hydroxyalkenal Species Directly from Lipid Extracts after One-Step in Situ Derivatization
- (2012) Miao Wang et al. ANALYTICAL CHEMISTRY
- Docosahexaenoic acid inhibition of inflammation is partially via cross-talk between Nrf2/heme oxygenase 1 and IKK/NF-κB pathways
- (2012) Ya-Chen Yang et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Anti-oxidative stress regulator NF-E2-related factor 2 mediates the adaptive induction of antioxidant and detoxifying enzymes by lipid peroxidation metabolite 4-hydroxynonenal
- (2012) Ying Huang et al. Cell and Bioscience
- Pro-inflammatory cytokines and lipopolysaccharide induce changes in cell morphology, and upregulation of ERK1/2, iNOS and sPLA2-IIA expression in astrocytes and microglia
- (2011) Wenwen Sheng et al. Journal of Neuroinflammation
- Docosahexaenoic acid modulates inflammatory and antineurogenic functions of activated microglial cells
- (2011) Maria Antonietta Ajmone-Cat et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Low concentration of 4-hydroxy hexenal increases heme oxygenase-1 expression through activation of Nrf2 and antioxidative activity in vascular endothelial cells
- (2010) Atsushi Ishikado et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Trans-4-hydroxy-2-hexenal, a product of n-3 fatty acid peroxidation: Make some room HNE…
- (2010) Eric K. Long et al. FREE RADICAL BIOLOGY AND MEDICINE
- Docosahexaenoic Acid Suppresses Neuroinflammatory Responses and Induces Heme Oxygenase-1 Expression in BV-2 Microglia: Implications of Antidepressant Effects for Omega-3 Fatty Acids
- (2010) Dah-Yuu Lu et al. NEUROPSYCHOPHARMACOLOGY
- Regulatory role of cytosolic phospholipase A2α in NADPH oxidase activity and in inducible nitric oxide synthase induction by aggregated Aβ1-42in microglia
- (2009) I. Szaingurten-Solodkin et al. GLIA
- The emerging role of group VI calcium-independent phospholipase A2in releasing docosahexaenoic acid from brain phospholipids: Fig. 1.
- (2008) Joshua T. Green et al. JOURNAL OF LIPID RESEARCH
- Docosahexaenoic acid prevents lipopolysaccharide-induced cytokine production in microglial cells by inhibiting lipopolysaccharide receptor presentation but not its membrane subdomain localization
- (2008) Véronique De Smedt-Peyrusse et al. JOURNAL OF NEUROCHEMISTRY
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