Transcriptome analysis of alcohol-treated microglia reveals downregulation of beta amyloid phagocytosis

Microglial-specific transcriptome changes following chronic alcohol consumption

(2018) Gizelle M. McCarthy et al.   NEUROPHARMACOLOGY

Long-term ethanol exposure: Temporal pattern of microRNA expression and associated mRNA gene networks in mouse brain

(2018) Elizabeth A. Osterndorff-Kahanek et al.   PLoS One

Cancer immunotherapy targeting the CD47/SIRPα axis

(2017) Kipp Weiskopf   EUROPEAN JOURNAL OF CANCER

Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity

(2017) Eva Czirr et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Engineering macrophages to eat cancer: from “marker of self” CD47 and phagocytosis to differentiation

(2017) Cory Alvey et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease

(2017) Carmen Venegas et al.   NATURE

The role of neuroimmune signaling in alcoholism

(2017) Fulton T. Crews et al.   NEUROPHARMACOLOGY

Risk factors associated with the onset and progression of Alzheimer’s disease: A systematic review of the evidence

(2017) Mona Hersi et al.   NEUROTOXICOLOGY

Beer Drinking Associates with Lower Burden of Amyloid Beta Aggregation in the Brain: Helsinki Sudden Death Series

(2016) Eloise H. Kok et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Effective Reduction of Acute Ethanol Withdrawal by the Tetracycline Derivative, Tigecycline, in Female and Male DBA/2J Mice

(2016) Joseph M. Martinez et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Impact of the Innate Immune Response in the Actions of Ethanol on the Central Nervous System

(2016) Jorge Montesinos et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

The Association Between Alcohol Use and the Progression of Alzheimer's Disease

(2016) Devorah Heymann et al.   Current Alzheimer Research

Calreticulin mutation does not contribute to disease progression in essential thrombocythemia by inhibiting phagocytosis

(2016) Shinya Daitoku et al.   EXPERIMENTAL HEMATOLOGY

Activation of phagocytic activity in astrocytes by reduced expression of the inflammasome component ASC and its implication in a mouse model of Alzheimer disease

(2016) Julien Couturier et al.   Journal of Neuroinflammation

Soluble IgM links apoptosis to complement activation in early alcoholic liver disease in mice

(2016) Rebecca L. Smathers et al.   MOLECULAR IMMUNOLOGY

Expansion of the Gene Ontology knowledgebase and resources

(2016)   NUCLEIC ACIDS RESEARCH

The neuroimmune transcriptome and alcohol dependence: potential for targeted therapies

(2016) Anna Warden et al.   PHARMACOGENOMICS

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

Association between alcohol and Alzheimer's disease

(2016) Wen-Juan Huang et al.   Experimental and Therapeutic Medicine

Mechanisms of Aβ Clearance and Degradation by Glial Cells

(2016) Miriam Ries et al.   Frontiers in Aging Neuroscience

The sequenced rat brain transcriptome - its use in identifying networks predisposing alcohol consumption

(2015) Laura M. Saba et al.   FEBS Journal

Transient activation of microglia following acute alcohol exposure in developing mouse neocortex is primarily driven by BAX-dependent neurodegeneration

(2015) Katelin E. Ahlers et al.   GLIA

Low concentrations of ethanol protect against synaptotoxicity induced by Aβ in hippocampal neurons

(2015) Gonzalo Muñoz et al.   NEUROBIOLOGY OF AGING

Ethanol-Induced TLR4/NLRP3 Neuroinflammatory Response in Microglial Cells Promotes Leukocyte Infiltration Across the BBB

(2015) Silvia Alfonso-Loeches et al.   NEUROCHEMICAL RESEARCH

Synaptic microRNAs Coordinately Regulate Synaptic mRNAs: Perturbation by Chronic Alcohol Consumption

(2015) Dana Most et al.   NEUROPSYCHOPHARMACOLOGY

Integrating mRNA and miRNA Weighted Gene Co-Expression Networks with eQTLs in the Nucleus Accumbens of Subjects with Alcohol Dependence

(2015) Mohammed Mamdani et al.   PLoS One

P2X4 Receptor Regulates Alcohol-Induced Responses in Microglia

(2014) Larisa Gofman et al.   Journal of Neuroimmune Pharmacology

Neurodegeneration by Activation of the Microglial Complement-Phagosome Pathway

(2014) L.-G. Bodea et al.   JOURNAL OF NEUROSCIENCE

Altered autophagy in the mice with a deficiency of saposin A and saposin B

(2013) Ying Sun et al.   Autophagy

Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation

(2013) Dora Lippai et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Ethanol induces TLR4/TLR2 association, triggering an inflammatory response in microglial cells

(2013) Sara Fernandez-Lizarbe et al.   JOURNAL OF NEUROCHEMISTRY

Mammalian iron transporters: Families SLC11 and SLC40

(2013) Nicolas Montalbetti et al.   MOLECULAR ASPECTS OF MEDICINE

Gene Expression in Brain and Liver Produced by Three Different Regimens of Alcohol Consumption in Mice: Comparison with Immune Activation

(2013) Elizabeth Osterndorff-Kahanek et al.   PLoS One

The impact of alcohol on Alzheimer's disease: A systematic review

(2012) Anna K. Piazza-Gardner et al.   AGING & MENTAL HEALTH

Coronin 1C harbours a second actin-binding site that confers co-operative binding to F-actin

(2012) Keefe T. Chan et al.   BIOCHEMICAL JOURNAL

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

High Mobility Group Box 1/Toll-like Receptor Danger Signaling Increases Brain Neuroimmune Activation in Alcohol Dependence

(2012) Fulton T. Crews et al.   BIOLOGICAL PSYCHIATRY

Ethanol suppresses phagosomal adhesion maturation, Rac activation, and subsequent actin polymerization during FcγR-mediated phagocytosis

(2012) John Karavitis et al.   CELLULAR IMMUNOLOGY

Novel Insights into V-ATPase Functioning: Distinct Roles for its Accessory Subunits ATP6AP1/Ac45 and ATP6AP2/(pro) Renin Receptor

(2012) Eric J.R. Jansen et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia

(2012) Hongjun Fu et al.   GLIA

Essential diurnal Rac1 activation during retinal phagocytosis requires αvβ5 integrin but not tyrosine kinases focal adhesion kinase or Mer tyrosine kinase

(2012) Yingyu Mao et al.   MOLECULAR BIOLOGY OF THE CELL

Effects of long-term moderate ethanol and cholesterol on cognition, cholinergic neurons, inflammation, and vascular impairment in rats

(2012) D. Ehrlich et al.   NEUROSCIENCE

Current alcohol consumption and its relationship to incident dementia: results from a 3-year follow-up study among primary care attenders aged 75 years and older

(2011) S. Weyerer et al.   AGE AND AGEING

Effects of chronic alcohol consumption on expression levels of APP and Aβ-producing enzymes

(2011) Sae-Rom Kim et al.   BMB Reports

Statistical methods on detecting differentially expressed genes for RNA-seq data

(2011) Zhongxue Chen et al.   BMC Systems Biology

Attenuation of microglial and IL-1 signaling protects mice from acute alcohol-induced sedation and/or motor impairment

(2011) Yue Wu et al.   BRAIN BEHAVIOR AND IMMUNITY

Minocycline reduces ethanol drinking

(2011) R.G. Agrawal et al.   BRAIN BEHAVIOR AND IMMUNITY

TLR4-MyD88 signalling: a molecular target for alcohol actions

(2011) Subhash C Pandey   BRITISH JOURNAL OF PHARMACOLOGY

Identification of a Cytochrome P4502E1/Bid/C1q-dependent Axis Mediating Inflammation in Adipose Tissue after Chronic Ethanol Feeding to Mice

(2011) Becky M. Sebastian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macrophage phagocytosis: effects of environmental pollutants, alcohol, cigarette smoke, and other external factors

(2011) John Karavitis et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Complement receptor 3 (CD11b/CD18) is implicated in the elimination of β-amyloid peptides

(2010) Nada Choucair-Jaafar et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Complement and Alcoholic Liver Disease: Role of C1q in the Pathogenesis of Ethanol-Induced Liver Injury in Mice

(2010) Jessica I. Cohen et al.   GASTROENTEROLOGY

Pivotal Role of TLR4 Receptors in Alcohol-Induced Neuroinflammation and Brain Damage

(2010) S. Alfonso-Loeches et al.   JOURNAL OF NEUROSCIENCE

Signal Regulatory Protein-β1

(2009) Sadanand Gaikwad et al.   AMERICAN JOURNAL OF PATHOLOGY

C5a Mediates Peripheral Blood Neutrophil Dysfunction in Critically Ill Patients

(2009) Andrew Conway Morris et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Fc RI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions

(2009) C. H. Serezani et al.   BLOOD

Critical Role of TLR4 Response in the Activation of Microglia Induced by Ethanol

(2009) S. Fernandez-Lizarbe et al.   JOURNAL OF IMMUNOLOGY

Blockade of chloride intracellular ion channel 1 stimulates Aβ phagocytosis

(2008) Silvia Paradisi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The genomic determinants of alcohol preference in mice

(2008) Boris Tabakoff et al.   MAMMALIAN GENOME

Lipid rafts regulate ethanol-induced activation of TLR4 signaling in murine macrophages

(2007) Sara Fernandez-Lizarbe et al.   MOLECULAR IMMUNOLOGY