ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy
出版年份 2017 全文链接
标题
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy
作者
关键词
-
出版物
NATURE
Volume 549, Issue 7673, Pages 523-527
出版商
Springer Nature
发表日期
2017-09-20
DOI
10.1038/nature24016
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- Impaired Autophagy in APOE4 Astrocytes
- (2016) Shira Simonovitch et al. JOURNAL OF ALZHEIMERS DISEASE
- TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
- (2016) Yaming Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
- (2016) Xing Liu et al. NATURE
- TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy
- (2016) Peng Yuan et al. NEURON
- Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice
- (2014) Oleg Butovsky et al. ANNALS OF NEUROLOGY
- APOε4 is associated with enhanced in vivo innate immune responses in human subjects
- (2014) Stephen C. Gale et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation
- (2013) Lea Tenenholz Grinberg et al. ACTA NEUROPATHOLOGICA
- Identification of a unique TGF-β–dependent molecular and functional signature in microglia
- (2013) Oleg Butovsky et al. NATURE NEUROSCIENCE
- Anti-Tau Antibodies that Block Tau Aggregate Seeding In Vitro Markedly Decrease Pathology and Improve Cognition In Vivo
- (2013) Kiran Yanamandra et al. NEURON
- National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
- (2012) Bradley T. Hyman et al. Alzheimers & Dementia
- Genomic Analysis of Reactive Astrogliosis
- (2012) J. L. Zamanian et al. JOURNAL OF NEUROSCIENCE
- Human APOE Isoform-Dependent Effects on Brain -Amyloid Levels in PDAPP Transgenic Mice
- (2009) K. R. Bales et al. JOURNAL OF NEUROSCIENCE
- Apolipoprotein E ε4 is associated with disease-specific effects on brain atrophy in Alzheimer's disease and frontotemporal dementia
- (2009) Federica Agosta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- β-amyloid burden is not associated with rates of brain atrophy
- (2007) Keith A. Josephs et al. ANNALS OF NEUROLOGY
- APOE genotype-specific differences in the innate immune response
- (2007) Michael P. Vitek et al. NEUROBIOLOGY OF AGING
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started