TAK1 mediates excessive autophagy via p38 and ERK in cisplatin-induced acute kidney injury

TAK1 as the mediator in the protective effect of propofol on renal interstitial fibrosis induced by ischemia/reperfusion injury

(2017) Huiping Wu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Crosstalk of autophagy and apoptosis: Involvement of the dual role of autophagy under ER stress

(2017) Shuling Song et al.   JOURNAL OF CELLULAR PHYSIOLOGY

TLR2 mediates autophagy through ERK signaling pathway in Mycoplasma gallisepticum -infected RAW264.7 cells

(2017) Ziyin Lu et al.   MOLECULAR IMMUNOLOGY

16-hydroxy-cleroda-3,13-dien-16,15-olide induced glioma cell autophagy via ROS generation and activation of p38 MAPK and ERK-1/2

(2016) Varadharajan Thiyagarajan et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Therapeutic effect of methyl salicylate 2- O -β- d -lactoside on LPS-induced acute lung injury by inhibiting TAK1/NF-kappaB phosphorylation and NLRP3 expression

(2016) Shengqian Yang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The dual role of autophagy under hypoxia-involvement of interaction between autophagy and apoptosis

(2015) Mengmeng Li et al.   APOPTOSIS

DNA damage response in cisplatin-induced nephrotoxicity

(2015) Shiyao Zhu et al.   ARCHIVES OF TOXICOLOGY

Neuron-Specific Tumor Necrosis Factor Receptor–Associated Factor 3 Is a Central Regulator of Neuronal Death in Acute Ischemic StrokeNovelty and Significance

(2015) Jun Gong et al.   HYPERTENSION

Autophagy Induces Prosenescent Changes in Proximal Tubular S3 Segments

(2015) A. Baisantry et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Docosahexaenoic acid inhibits inflammation via free fatty acid receptor FFA4, disruption of TAB2 interaction with TAK1/TAB1 and downregulation of ERK-dependent Egr-1 expression in EA.hy926 cells

(2015) Kai-Li Liu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

An integrated view of cisplatin-induced nephrotoxicity and ototoxicity

(2015) Takatoshi Karasawa et al.   TOXICOLOGY LETTERS

The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation

(2015) Yongjie Wei et al.   eLife

ATGs

(2014) Nuria Martinez-Lopez et al.   Autophagy

Activation of the MAPK11/12/13/14 (p38 MAPK) pathway regulates the transcription of autophagy genes in response to oxidative stress induced by a novel copper complex in HeLa cells

(2014) Wu Zhong et al.   Autophagy

TAK1 control of cell death

(2014) S R Mihaly et al.   CELL DEATH AND DIFFERENTIATION

Phosphorylation of heat shock protein 27 antagonizes TNF-α induced HeLa cell apoptosis via regulating TAK1 ubiquitination and activation of p38 and ERK signaling

(2014) Zhilin Qi et al.   CELLULAR SIGNALLING

Autophagy: a double-edged sword for neuronal survival after cerebral ischemia

(2014) Kangyong Liu et al.   Neural Regeneration Research

Autophagy and Its Effects: Making Sense of Double-Edged Swords

(2014) Andrew Thorburn   PLOS BIOLOGY

Frequency of TGF-βand IFN-γGenotype as Risk Factors for Acute Kidney Injury and Death in Intensive Care Unit Patients

(2014) Caren Cristina Grabulosa et al.   Biomed Research International

Energy deprivation by silibinin in colorectal cancer cells

(2013) Komal Raina et al.   Autophagy

Molecular determinants of response to cisplatin-based neoadjuvant chemotherapy

(2013) Joaquim Bellmunt et al.   CURRENT OPINION IN UROLOGY

Genetic deficiency of adiponectin protects against acute kidney injury

(2013) Xiaogao Jin et al.   KIDNEY INTERNATIONAL

TAK1 regulates autophagic cell death by suppressing the phosphorylation of p70 S6 kinase 1

(2013) Ju Hyun Shin et al.   Scientific Reports

Lobolide, a diterpene, blockades the NF-κB pathway and p38 and ERK MAPK activity in macrophages in vitro

(2012) Xiao-fen Lv et al.   ACTA PHARMACOLOGICA SINICA

Autophagy Guards Against Cisplatin-Induced Acute Kidney Injury

(2012) Atsushi Takahashi et al.   AMERICAN JOURNAL OF PATHOLOGY

Proteasome inhibition-induced p38 MAPK/ERK signaling regulates autophagy and apoptosis through the dual phosphorylation of glycogen synthase kinase 3β

(2012) Cheol-Hee Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Double-Edged Sword with Therapeutic Potential: An Updated Role of Autophagy in Ischemic Cerebral Injury

(2012) Kai Wei et al.   CNS Neuroscience & Therapeutics

Why is autophagy important in human diseases?

(2012) Kaipeng Jing et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

TAK1, more than just innate immunity

(2012) Liang Dai et al.   IUBMB LIFE

Autophagy Promotes Intracellular Degradation of Type I Collagen Induced by Transforming Growth Factor (TGF)-β1

(2012) Sung Il Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quercetin enhances ABCA1 expression and cholesterol efflux through a p38-dependent pathway in macrophages

(2012) Yu-Cheng Chang et al.   JOURNAL OF LIPID RESEARCH

Autophagy in proximal tubules protects against acute kidney injury

(2012) Man Jiang et al.   KIDNEY INTERNATIONAL

TGF-β Signaling via TAK1 Pathway: Role in Kidney Fibrosis

(2012) Mary E. Choi et al.   SEMINARS IN NEPHROLOGY

zVAD-induced autophagic cell death requires c-Src-dependent ERK and JNK activation and reactive oxygen species generation

(2011) Szu-Ying Chen et al.   Autophagy

Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors

(2011) Vojo Deretic   CURRENT OPINION IN IMMUNOLOGY

Autophagy Is a Component of Epithelial Cell Fate in Obstructive Uropathy

(2010) Ling Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

(2010) Hilla Weidberg et al.   EMBO JOURNAL

Selective degradation of p62 by autophagy

(2010) Yoshinobu Ichimura et al.   Seminars in Immunopathology

When autophagy meets viruses: a double-edged sword with functions in defense and offense

(2010) Hee Jin Kim et al.   Seminars in Immunopathology

The cell cycle and acute kidney injury

(2009) Peter M. Price et al.   KIDNEY INTERNATIONAL

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Participation of autophagy in renal ischemia/reperfusion injury

(2008) Chigure Suzuki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

To Die or Not to Die: That is the Autophagic Question

(2008) Maria Maiuri et al.   CURRENT MOLECULAR MEDICINE