miRNA targeting and alternative splicing in the stress response – events hosted by membrane-less compartments

Stress-dependent miR-980 regulation of Rbfox1/A2bp1 promotes ribonucleoprotein granule formation and cell survival

(2018) Mariya M. Kucherenko et al.   Nature Communications

ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway

(2017) Yang Zhao et al.   Molecular Cancer

Clinical implications of cellular stress responses

(2017) Borut Poljšak et al.   Bosnian Journal of Basic Medical Sciences

Vulnerability of microRNA biogenesis in FTD–ALS

(2016) Chen Eitan et al.   BRAIN RESEARCH

Rbfox Proteins Regulate Splicing as Part of a Large Multiprotein Complex LASR

(2016) Andrey Damianov et al.   CELL

Coexisting Liquid Phases Underlie Nucleolar Subcompartments

(2016) Marina Feric et al.   CELL

MicroRNA-dependent roles of Drosha and Pasha in the Drosophila larval ovary morphogenesis

(2016) Huiming Yang et al.   DEVELOPMENTAL BIOLOGY

Repression of Pumilio Protein Expression by Rbfox1 Promotes Germ Cell Differentiation

(2016) Arnaldo Carreira-Rosario et al.   DEVELOPMENTAL CELL

Droplet organelles?

(2016) Edward M Courchaine et al.   EMBO JOURNAL

Reversible HuR‐microRNA binding controls extracellular export of miR‐122 and augments stress response

(2016) Kamalika Mukherjee et al.   EMBO REPORTS

Nup358 binds to AGO proteins through its SUMO‐interacting motifs and promotes the association of target mRNA with miRISC

(2016) Manas Ranjan Sahoo et al.   EMBO REPORTS

microRNAs target SRSF7 splicing factor to modulate the expression of osteopontin splice variants in renal cancer cells

(2016) Joanna Boguslawska et al.   GENE

Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet

(2016) I. O. Cicek et al.   GENETICS

Dancing Protein Clouds: The Strange Biology and Chaotic Physics of Intrinsically Disordered Proteins

(2016) Vladimir N. Uversky   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytoplasmic Rbfox1 Regulates the Expression of Synaptic and Autism-Related Genes

(2016) Ji-Ann Lee et al.   NEURON

A continuum of mRNP complexes in embryonic microRNA-mediated silencing

(2016) Edlyn Wu et al.   NUCLEIC ACIDS RESEARCH

Alternative splicing affects the subcellular localization of Drosha

(2016) Steffen Link et al.   NUCLEIC ACIDS RESEARCH

Rbfox proteins regulate microRNA biogenesis by sequence-specific binding to their precursors and target downstream Dicer

(2016) Yu Chen et al.   NUCLEIC ACIDS RESEARCH

The DBHS proteins SFPQ, NONO and PSPC1: a multipurpose molecular scaffold

(2016) Gavin J. Knott et al.   NUCLEIC ACIDS RESEARCH

Getting Access to Low-Complexity Domain Modifications

(2016) Roland Schüller et al.   TRENDS IN BIOCHEMICAL SCIENCES

Analysis of microRNA and Gene Expression Profiles in Multiple Sclerosis: Integrating Interaction Data to Uncover Regulatory Mechanisms

(2016) Sherry Freiesleben et al.   Scientific Reports

Stress granules, P-bodies and cancer

(2015) Paul Anderson et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

Nuclear bodies: the emerging biophysics of nucleoplasmic phases

(2015) Lian Zhu et al.   CURRENT OPINION IN CELL BIOLOGY

Intrinsically disordered proteins: emerging interaction specialists

(2015) Peter Tompa et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Dysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: a new mechanism for ALS

(2015) A. Emde et al.   EMBO JOURNAL

Competition between RNA-binding proteins CELF1 and HuR modulates MYC translation and intestinal epithelium renewal

(2015) Lan Liu et al.   MOLECULAR BIOLOGY OF THE CELL

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

(2015) Yuan Lin et al.   MOLECULAR CELL

Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles

(2015) Timothy J. Nott et al.   MOLECULAR CELL

Stress Induces p38 MAPK-Mediated Phosphorylation and Inhibition of Drosha-Dependent Cell Survival

(2015) Qian Yang et al.   MOLECULAR CELL

Comprehensive analysis of microRNA expression profile in malignant glioma tissues

(2015) Monika Piwecka et al.   Molecular Oncology

Polymer physics of intracellular phase transitions

(2015) Clifford P. Brangwynne et al.   Nature Physics

Intrinsically disordered proteins in cellular signalling and regulation

(2015) Peter E. Wright et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics

(2015) Shana Elbaum-Garfinkle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An RNA biosensor for imaging the first round of translation from single cells to living animals

(2015) J. M. Halstead et al.   SCIENCE

Emerging Roles of Disordered Sequences in RNA-Binding Proteins

(2015) Sara Calabretta et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mitochondrial RNA Granules Are Centers for Posttranscriptional RNA Processing and Ribosome Biogenesis

(2015) Hana Antonicka et al.   Cell Reports

SmD1 Modulates the miRNA Pathway Independently of Its Pre-mRNA Splicing Function

(2015) Xiao-Peng Xiong et al.   PLoS Genetics

Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules

(2015) Sonja Kroschwald et al.   eLife

Role of the cytoplasmic isoform of RBFOX1/A2BP1 in establishing the architecture of the developing cerebral cortex

(2015) Nanako Hamada et al.   Molecular Autism

Soma influences GSC progeny differentiation via the cell adhesion-mediated steroid-let-7-Wingless signaling cascade that regulates chromatin dynamics

(2015) A. Konig et al.   Biology Open

Liquid-Liquid Phase Separation in Biology

(2014) Anthony A. Hyman et al.   Annual Review of Cell and Developmental Biology

Drosophila miR-9a Targets the ECM Receptor Dystroglycan to Canalize Myotendinous Junction Formation

(2014) Andriy S. Yatsenko et al.   DEVELOPMENTAL CELL

Context-dependent control of alternative splicing by RNA-binding proteins

(2014) Xiang-Dong Fu et al.   NATURE REVIEWS GENETICS

Interplay between pre-mRNA splicing and microRNA biogenesis within the supraspliceosome

(2014) Lily Agranat-Tamir et al.   NUCLEIC ACIDS RESEARCH

mRNP granules

(2014) J Ross Buchan   RNA Biology

Nucleoli and Stress Granules: Connecting Distant Relatives

(2014) Hicham Mahboubi et al.   TRAFFIC

Drosha Promotes Splicing of a Pre-microRNA-like Alternative Exon

(2014) Mallory A. Havens et al.   PLoS Genetics

Nucleolar stress with and without p53

(2014) Allison James et al.   Nucleus

CELFish ways to modulate mRNA decay

(2013) Irina Vlasova-St. Louis et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Phosphorylation-Regulated Binding of RNA Polymerase II to Fibrous Polymers of Low-Complexity Domains

(2013) Ilmin Kwon et al.   CELL

Two new and distinct roles for Drosophila Argonaute-2 in the nucleus: alternative pre-mRNA splicing and transcriptional repression

(2013) J. M. Taliaferro et al.   GENES & DEVELOPMENT

Environmental stress, ageing and glial cell senescence: a novel mechanistic link to Parkinson's disease?

(2013) S. J. Chinta et al.   JOURNAL OF INTERNAL MEDICINE

Hippocampal gene expression changes underlying stress sensitization and recovery

(2013) J D Gray et al.   MOLECULAR PSYCHIATRY

EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2

(2013) Jia Shen et al.   NATURE

How cells get the message: dynamic assembly and function of mRNA–protein complexes

(2013) Michaela Müller-McNicoll et al.   NATURE REVIEWS GENETICS

miRNA Biogenesis Enzyme Drosha Is Required for Vascular Smooth Muscle Cell Survival

(2013) Pei Fan et al.   PLoS One

Stress-induced ECM alteration modulates cellular microRNAs that feedback to readjust the extracellular environment and cell behavior

(2013) Evgeniia V. Edeleva et al.   Frontiers in Genetics

Rare inheritedA2BP1deletion in a proband with autism and developmental hemiparesis

(2012) L.K. Davis et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Dg-Dys-Syn1 signaling in Drosophila regulates the microRNA profile

(2012) April K Marrone et al.   BMC CELL BIOLOGY

MicroRNAs in Stress Signaling and Human Disease

(2012) Joshua T. Mendell et al.   CELL

Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

(2012) Masato Kato et al.   CELL

Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies

(2012) Tina W. Han et al.   CELL

Role of MicroRNA Processing in Adipose Tissue in Stress Defense and Longevity

(2012) Marcelo A. Mori et al.   Cell Metabolism

Steroid-induced microRNAlet-7acts as a spatio-temporal code for neuronal cell fate in the developingDrosophilabrain

(2012) Mariya M Kucherenko et al.   EMBO JOURNAL

Functional Importance of Dicer Protein in the Adaptive Cellular Response to Hypoxia

(2012) J. J. David Ho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulated protein aggregation: stress granules and neurodegeneration

(2012) Benjamin Wolozin   Molecular Neurodegeneration

TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes

(2012) Y. Kawahara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The p53 network: cellular and systemic DNA damage responses in aging and cancer

(2012) H. Christian Reinhardt et al.   TRENDS IN GENETICS

Sequestration of Highly Expressed mRNAs in Cytoplasmic Granules, P-Bodies, and Stress Granules Enhances Cell Viability

(2012) Anna Lavut et al.   PLoS Genetics

Cajal bodies: where form meets function

(2012) Martin Machyna et al.   Wiley Interdisciplinary Reviews-RNA

p53 -Dependent and -Independent Nucleolar Stress Responses

(2012) Karl Holmberg Olausson et al.   Cells

MicroRNA-binding is required for recruitment of human Argonaute 2 to stress granules and P-bodies

(2011) Justin M. Pare et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ecdysteroids affectDrosophilaovarian stem cell niche formation and early germline differentiation

(2011) Annekatrin König et al.   EMBO JOURNAL

Shuttling SR proteins: more than splicing factors

(2011) Laure Twyffels et al.   FEBS Journal

Nucleolin Protein Interacts with Microprocessor Complex to Affect Biogenesis of MicroRNAs 15a and 16

(2011) Brian F. Pickering et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Polypyrimidine Tract-Binding Protein Affects Coronavirus RNA Accumulation Levels and Relocalizes Viral RNAs to Novel Cytoplasmic Domains Different from Replication-Transcription Sites

(2011) I. Sola et al.   JOURNAL OF VIROLOGY

Hypoxia Potentiates MicroRNA-Mediated Gene Silencing through Posttranslational Modification of Argonaute2

(2011) C. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

Nucleation of nuclear bodies by RNA

(2011) Sergey P. Shevtsov et al.   NATURE CELL BIOLOGY

The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain

(2011) Lauren T Gehman et al.   NATURE GENETICS

Controlling gene expression in response to stress

(2011) Eulàlia de Nadal et al.   NATURE REVIEWS GENETICS

Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes

(2011) C. P. Brangwynne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA Granules in Germ Cells

(2011) E. Voronina et al.   Cold Spring Harbor Perspectives in Biology

The importance of CELF control: molecular and biological roles of the CUG-BP, Elav-like family of RNA-binding proteins

(2011) Twishasri Dasgupta et al.   Wiley Interdisciplinary Reviews-RNA

Essential Role of Coiled Coils for Aggregation and Activity of Q/N-Rich Prions and PolyQ Proteins

(2010) Ferdinando Fiumara et al.   CELL

Evaluation of A2BP1 as an Obesity Gene

(2010) L. Ma et al.   DIABETES

MAPK signalling in cellular metabolism: stress or wellness?

(2010) Helmuth Gehart et al.   EMBO REPORTS

MicroRNAs coordinate an alternative splicing network during mouse postnatal heart development

(2010) A. Kalsotra et al.   GENES & DEVELOPMENT

A2BP1 as a novel susceptible gene for primary biliary cirrhosis in Japanese patients

(2010) Satoru Joshita et al.   HUMAN IMMUNOLOGY

MicroRNA Functions in Stress Responses

(2010) Anthony K.L. Leung et al.   MOLECULAR CELL

The Nucleolus under Stress

(2010) Séverine Boulon et al.   MOLECULAR CELL

The Heat Shock Response: Life on the Verge of Death

(2010) Klaus Richter et al.   MOLECULAR CELL

Cell stress is related to re-localization of Argonaute 2 and to decreased RNA interference in human cells

(2010) Anke Detzer et al.   NUCLEIC ACIDS RESEARCH

The Cajal Body and Histone Locus Body

(2010) Z. Nizami et al.   Cold Spring Harbor Perspectives in Biology

Paraspeckles

(2010) A. H. Fox et al.   Cold Spring Harbor Perspectives in Biology

Protein aggregation as a paradigm of aging

(2009) Ariel B. Lindner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Signaling to p53: Ribosomal Proteins Find Their Way

(2009) Yanping Zhang et al.   CANCER CELL

Paraspeckles: nuclear bodies built on long noncoding RNA

(2009) Charles S. Bond et al.   JOURNAL OF CELL BIOLOGY

Functional Association of the Microprocessor Complex with the Spliceosome

(2009) N. Kataoka et al.   MOLECULAR AND CELLULAR BIOLOGY

An Architectural Role for a Nuclear Noncoding RNA: NEAT1 RNA Is Essential for the Structure of Paraspeckles

(2009) Christine M. Clemson et al.   MOLECULAR CELL

Eukaryotic Stress Granules: The Ins and Outs of Translation

(2009) J. Ross Buchan et al.   MOLECULAR CELL

Dicer is regulated by cellular stresses and interferons

(2009) Jennifer L. Wiesen et al.   MOLECULAR IMMUNOLOGY

The GW182 protein family in animal cells: New insights into domains required for miRNA-mediated gene silencing

(2009) A. Eulalio et al.   RNA

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

(2009) C. P. Brangwynne et al.   SCIENCE

Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies

(2008) Yan Zeng et al.   BIOCHEMICAL JOURNAL

Primary microRNA transcript retention at sites of transcription leads to enhanced microRNA production

(2008) Jan M. Pawlicki et al.   JOURNAL OF CELL BIOLOGY

Prolyl 4-hydroxylation regulates Argonaute 2 stability

(2008) Hank H. Qi et al.   NATURE

GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay

(2008) Ana Eulalio et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The splicing factor SC35 has an active role in transcriptional elongation

(2008) Shengrong Lin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dual localization of the RNA binding protein CUGBP-1 to stress granule and perinucleolar compartment

(2007) Ken Fujimura et al.   EXPERIMENTAL CELL RESEARCH

Argonaute proteins: key players in RNA silencing

(2007) Gyorgy Hutvagner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY