Alternative splicing affects the subcellular localization of Drosha

Structure of Human DROSHA

(2016) S. Chul Kwon et al.   CELL

Functional Anatomy of the Human Microprocessor

(2015) Tuan Anh Nguyen et al.   CELL

Stress Induces p38 MAPK-Mediated Phosphorylation and Inhibition of Drosha-Dependent Cell Survival

(2015) Qian Yang et al.   MOLECULAR CELL

Drosha controls dendritic cell development by cleaving messenger RNAs encoding inhibitors of myelopoiesis

(2015) Timothy M Johanson et al.   NATURE IMMUNOLOGY

Swiss army knives: non-canonical functions of nuclear Drosha and Dicer

(2015) Kaspar Burger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rare Drosha Splice Variants Are Deficient in MicroRNA Processing but Do Not Affect General MicroRNA Expression in Cancer Cells

(2015) Stefanie E. Grund et al.   NEOPLASIA

Analysis of nuclear RNA interference in human cells by subcellular fractionation and Argonaute loading

(2014) Keith T Gagnon et al.   Nature Protocols

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Drosha as an interferon-independent antiviral factor

(2014) J. S. Shapiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drosha Promotes Splicing of a Pre-microRNA-like Alternative Exon

(2014) Mallory A. Havens et al.   PLoS Genetics

Cellular functions of the microprocessor

(2013) Sara Macias et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Loop-miRs: active microRNAs generated from single-stranded loop regions

(2013) Julia Winter et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells

(2013) A Formosa et al.   ONCOGENE

miRNA Biogenesis Enzyme Drosha Is Required for Vascular Smooth Muscle Cell Survival

(2013) Pei Fan et al.   PLoS One

Phosphorylation of DGCR8 Increases Its Intracellular Stability and Induces a Progrowth miRNA Profile

(2013) Kristina M. Herbert et al.   Cell Reports

Drosha Regulates Gene Expression Independently of RNA Cleavage Function

(2013) Natalia Gromak et al.   Cell Reports

Toward a Comprehensive Characterization of a Human Cancer Cell Phosphoproteome

(2012) Houjiang Zhou et al.   JOURNAL OF PROTEOME RESEARCH

Drosha regulates neurogenesis by controlling Neurogenin 2 expression independent of microRNAs

(2012) Philip Knuckles et al.   NATURE NEUROSCIENCE

Evidence for a cytoplasmic microprocessor of pri-miRNAs

(2012) J. S. Shapiro et al.   RNA

In-vivo quantification of primary microRNA processing by Drosha with a luciferase based system

(2011) Danilo Allegra et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival

(2011) E A Afanasyeva et al.   CELL DEATH AND DIFFERENTIATION

Shuttling SR proteins: more than splicing factors

(2011) Laure Twyffels et al.   FEBS Journal

Gene silencing by microRNAs: contributions of translational repression and mRNA decay

(2011) Eric Huntzinger et al.   NATURE REVIEWS GENETICS

Depletion of key protein components of the RISC pathway impairs pre-ribosomal RNA processing

(2011) Xue-hai Liang et al.   NUCLEIC ACIDS RESEARCH

Glycogen Synthase Kinase 3 Beta (GSK3β) Phosphorylates the RNAase III Enzyme Drosha at S300 and S302

(2011) Xiaoli Tang et al.   PLoS One

Argonaute proteins regulate microRNA stability: Increased microRNA abundance by Argonaute proteins is due to microRNA stabilization

(2011) Julia Winter et al.   RNA Biology

Diverse Endonucleolytic Cleavage Sites in the Mammalian Transcriptome Depend upon MicroRNAs, Drosha, and Additional Nucleases

(2010) Fedor V. Karginov et al.   MOLECULAR CELL

MicroRNA Functions in Stress Responses

(2010) Anthony K.L. Leung et al.   MOLECULAR CELL

Phosphorylation of the RNase III enzyme Drosha at Serine300 or Serine302 is required for its nuclear localization

(2010) Xiaoli Tang et al.   NUCLEIC ACIDS RESEARCH

Posttranscriptional Crossregulation between Drosha and DGCR8

(2009) Jinju Han et al.   CELL

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

Small silencing RNAs: an expanding universe

(2009) Megha Ghildiyal et al.   NATURE REVIEWS GENETICS

Genome-wide identification of targets of the drosha-pasha/DGCR8 complex

(2009) S. Kadener et al.   RNA

Post-transcriptional control of DGCR8 expression by the Microprocessor

(2009) R. Triboulet et al.   RNA

The SR protein family

(2009) Peter J Shepard et al.   GENOME BIOLOGY

The SR protein family of splicing factors: master regulators of gene expression

(2008) Jennifer C. Long et al.   BIOCHEMICAL JOURNAL

Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA

(2008) Inha Heo et al.   MOLECULAR CELL

Identification and Characterization of a General Nuclear Translocation Signal in Signaling Proteins

(2008) Dana Chuderland et al.   MOLECULAR CELL

Coexpression of Argonaute-2 enhances RNA interference toward perfect match binding sites

(2008) S. Diederichs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Global View of Gene Activity and Alternative Splicing by Deep Sequencing of the Human Transcriptome

(2008) M. Sultan et al.   SCIENCE

Argonaute proteins: key players in RNA silencing

(2007) Gyorgy Hutvagner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY