Nuclear PTEN deficiency causes microcephaly with decreased neuronal soma size and increased seizure susceptibility

Characterization of PTEN mutations in brain cancer reveals that pten mono-ubiquitination promotes protein stability and nuclear localization

(2017) Jr-M Yang et al.   ONCOGENE

Dynamin-Related Protein 1 Deficiency Leads to Receptor-Interacting Protein Kinase 3–Mediated Necroptotic Neurodegeneration

(2016) Tatsuya Yamada et al.   AMERICAN JOURNAL OF PATHOLOGY

The PTEN protein: cellular localization and post-translational regulation

(2016) N. R. Leslie et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Coincident Phosphatidic Acid Interaction Restrains Drp1 in Mitochondrial Division

(2016) Yoshihiro Adachi et al.   MOLECULAR CELL

Functional diversity of astrocytes in neural circuit regulation

(2016) Lucile Ben Haim et al.   NATURE REVIEWS NEUROSCIENCE

Autistic-Like Traits and Cerebellar Dysfunction in Purkinje Cell PTEN Knock-Out Mice

(2015) Dario Cupolillo et al.   NEUROPSYCHOPHARMACOLOGY

Opening the conformation is a master switch for the dual localization and phosphatase activity of PTEN

(2015) Hoai-Nghia Nguyen et al.   Scientific Reports

PTEN

(2014) Carolyn A. Worby et al.   Annual Review of Biochemistry

Immunocytochemical markers of neuronal maturation in human diagnostic neuropathology

(2014) Harvey B. Sarnat   CELL AND TISSUE RESEARCH

Parkin‐independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain

(2014) Yusuke Kageyama et al.   EMBO JOURNAL

A new class of cancer-associated PTEN mutations defined by membrane translocation defects

(2014) H-N Nguyen et al.   ONCOGENE

Engineering ePTEN, an enhanced PTEN with increased tumor suppressor activities

(2014) Hoai-Nghia Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disorders

(2014) Patricia Kreis et al.   Frontiers in Molecular Neuroscience

Brain patterning perturbations following PTEN loss

(2014) Biliana O. Veleva-Rotse et al.   Frontiers in Molecular Neuroscience

Cowden Syndrome and the PTEN Hamartoma Tumor Syndrome: Systematic Review and Revised Diagnostic Criteria

(2013) R. Pilarski et al.   JNCI-Journal of the National Cancer Institute

New avenues for anti-epileptic drug discovery and development

(2013) Wolfgang Löscher et al.   NATURE REVIEWS DRUG DISCOVERY

Mechanism of human PTEN localization revealed by heterologous expression in Dictyostelium

(2013) H N Nguyen et al.   ONCOGENE

Nuclear PTEN Controls DNA Repair and Sensitivity to Genotoxic Stress

(2013) C. Bassi et al.   SCIENCE

PTEN signaling in autism spectrum disorders

(2012) Jing Zhou et al.   CURRENT OPINION IN NEUROBIOLOGY

Endogenous viruses: insights into viral evolution and impact on host biology

(2012) Cédric Feschotte et al.   NATURE REVIEWS GENETICS

Nuclear PTEN Regulates the APC-CDH1 Tumor-Suppressive Complex in a Phosphatase-Independent Manner

(2011) Min Sup Song et al.   CELL

Different Conformations of Phosphatase and Tensin Homolog, Deleted on Chromosome 10 (PTEN) Protein within the Nucleus and Cytoplasm of Neurons

(2011) Vera L. Moncalero et al.   PLoS One

Astrocyte heterogeneity: an underappreciated topic in neurobiology

(2010) Ye Zhang et al.   CURRENT OPINION IN NEUROBIOLOGY

PTEN hamartoma tumor syndrome: An overview

(2009) Judith A Hobert et al.   GENETICS IN MEDICINE

PTEN and the PI3-Kinase Pathway in Cancer

(2008) Nader Chalhoub et al.   Annual Review of Pathology-Mechanisms of Disease

The nuclear affairs of PTEN

(2008) S. M. Planchon et al.   JOURNAL OF CELL SCIENCE

The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network

(2008) Min Sup Song et al.   NATURE

PTEN signaling in brain: neuropathology and tumorigenesis

(2008) R Endersby et al.   ONCOGENE

The roles of PTEN in development, physiology and tumorigenesis in mouse models: a tissue-by-tissue survey

(2008) C B Knobbe et al.   ONCOGENE