Characterization of PTEN mutations in brain cancer reveals that pten mono-ubiquitination promotes protein stability and nuclear localization

Migration Phenotype of Brain-Cancer Cells Predicts Patient Outcomes

(2016) Chris L. Smith et al.   Cell Reports

Engineering PTEN function: Membrane association and activity

(2015) Jr-Ming Yang et al.   METHODS

Analysis of PTEN ubiquitylation and SUMOylation using molecular traps

(2015) Valérie Lang et al.   METHODS

Human Cerebrospinal Fluid Regulates Proliferation and Migration of Stem Cells Through Insulin-Like Growth Factor-1

(2015) Mingxin Zhu et al.   STEM CELLS AND DEVELOPMENT

A leak pathway for luminal protons in endosomes drives oncogenic signalling in glioblastoma

(2015) Kalyan C. Kondapalli et al.   Nature Communications

Opening the conformation is a master switch for the dual localization and phosphatase activity of PTEN

(2015) Hoai-Nghia Nguyen et al.   Scientific Reports

Pre-Exposure of Human Adipose Mesenchymal Stem Cells to Soluble Factors Enhances Their Homing to Brain Cancer

(2015) Chris L. Smith et al.   Stem Cells Translational Medicine

Cancer-Associated PTEN Mutants Act in a Dominant-Negative Manner to Suppress PTEN Protein Function

(2014) Antonella Papa et al.   CELL

Mesenchymal Stem Cells from Human Fat Engineered to Secrete BMP4 Are Nononcogenic, Suppress Brain Cancer, and Prolong Survival

(2014) Q. Li et al.   CLINICAL CANCER RESEARCH

Glucose-6–phosphatase Is a Key Metabolic Regulator of Glioblastoma Invasion

(2014) Sara Abbadi et al.   MOLECULAR CANCER RESEARCH

A new class of cancer-associated PTEN mutations defined by membrane translocation defects

(2014) H-N Nguyen et al.   ONCOGENE

Influence of Basement Membrane Proteins and Endothelial Cell-Derived Factors on the Morphology of Human Fetal-Derived Astrocytes in 2D

(2014) Amanda F. Levy et al.   PLoS One

Engineering ePTEN, an enhanced PTEN with increased tumor suppressor activities

(2014) Hoai-Nghia Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-cultured human adipose-derived mesenchymal stem cells are non-oncogenic and have enhanced viability, motility and tropism to brain cancer

(2014) Y Feng et al.   Cell Death & Disease

Establishing percent resection and residual volume thresholds affecting survival and recurrence for patients with newly diagnosed intracranial glioblastoma

(2013) Kaisorn L. Chaichana et al.   NEURO-ONCOLOGY

Mechanism of human PTEN localization revealed by heterologous expression in Dictyostelium

(2013) H N Nguyen et al.   ONCOGENE

Nuclear PTEN Controls DNA Repair and Sensitivity to Genotoxic Stress

(2013) C. Bassi et al.   SCIENCE

Phosphorylation-mediated PTEN conformational closure and deactivation revealed with protein semisynthesis

(2013) David Bolduc et al.   eLife

Shear Forces during Blast, Not Abrupt Changes in Pressure Alone, Generate Calcium Activity in Human Brain Cells

(2012) Rea Ravin et al.   PLoS One

Regulation of Brain Tumor Dispersal by NKCC1 Through a Novel Role in Focal Adhesion Regulation

(2012) Tomas Garzon-Muvdi et al.   PLOS BIOLOGY

Non-viral gene delivery nanoparticles based on Poly(β-amino esters) for treatment of glioblastoma

(2011) Stephany Y. Tzeng et al.   BIOMATERIALS

Nuclear PTEN Regulates the APC-CDH1 Tumor-Suppressive Complex in a Phosphatase-Independent Manner

(2011) Min Sup Song et al.   CELL

Dictyostelium huntingtin controls chemotaxis and cytokinesis through the regulation of myosin II phosphorylation

(2011) Yu Wang et al.   MOLECULAR BIOLOGY OF THE CELL

Integration and analysis of genome-scale data from gliomas

(2011) Gregory Riddick et al.   Nature Reviews Neurology

Cytoarchitecture of the lateral ganglionic eminence and rostral extension of the lateral ventricle in the human fetal brain

(2010) Hugo Guerrero-Cázares et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Surgical outcomes for older patients with glioblastoma multiforme: preoperative factors associated with decreased survival

(2010) Kaisorn L. Chaichana et al.   JOURNAL OF NEUROSURGERY

Proteomic identification of phosphatidylinositol (3,4,5) triphosphate-binding proteins in Dictyostelium discoideum

(2010) P. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Guided Cell Migration on Microtextured Substrates with Variable Local Density and Anisotropy

(2009) Deok-Ho Kim et al.   ADVANCED FUNCTIONAL MATERIALS

Mechanosensitivity of fibroblast cell shape and movement to anisotropic substratum topography gradients

(2009) Deok-Ho Kim et al.   BIOMATERIALS

Intra-operatively obtained human tissue: Protocols and techniques for the study of neural stem cells

(2009) Kaisorn L. Chaichana et al.   JOURNAL OF NEUROSCIENCE METHODS

Crucial role of the C-terminus of PTEN in antagonizing NEDD4-1-mediated PTEN ubiquitination and degradation

(2008) Xinjiang Wang et al.   BIOCHEMICAL JOURNAL

Tenets of PTEN Tumor Suppression

(2008) Leonardo Salmena et al.   CELL

PIP3-Independent Activation of TorC2 and PKB at the Cell's Leading Edge Mediates Chemotaxis

(2008) Yoichiro Kamimura et al.   CURRENT BIOLOGY

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

PTEN signaling in brain: neuropathology and tumorigenesis

(2008) R Endersby et al.   ONCOGENE