Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase

Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation

(2017) Yong-Jian Wang et al.   NATURE CELL BIOLOGY

Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP

(2017) Li Zhang et al.   eLife

Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene

(2017) Emma C. L. Cook et al.   PLoS One

Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts

(2015) Bei-Bei Chu et al.   CELL

The E3 Ubiquitin Ligase MARCH6 Degrades Squalene Monooxygenase and Affects 3-Hydroxy-3-Methyl-Glutaryl Coenzyme A Reductase and the Cholesterol Synthesis Pathway

(2014) N. Zelcer et al.   MOLECULAR AND CELLULAR BIOLOGY

Ubiquitin Ligases in Cholesterol Metabolism

(2014) Wei Jiang et al.   Diabetes & Metabolism Journal

The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1

(2013) Pei-Shan Li et al.   NATURE MEDICINE

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Ablation of gp78 in Liver Improves Hyperlipidemia and Insulin Resistance by Inhibiting SREBP to Decrease Lipid Biosynthesis

(2012) Tong-Fei Liu et al.   Cell Metabolism

Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system

(2012) Yien Che Tsai et al.   MOLECULAR BIOLOGY OF THE CELL

A Systematic Search for Endoplasmic Reticulum (ER) Membrane-associated RING Finger Proteins Identifies Nixin/ZNRF4 as a Regulator of Calnexin Stability and ER Homeostasis

(2011) Albert Neutzner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8

(2011) Y. Jo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake

(2010) L. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cholesterol Absorption Inhibitor Ezetimibe Acts by Blocking the Sterol-Induced Internalization of NPC1L1

(2008) Liang Ge et al.   Cell Metabolism