Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation

Genome-wide meta-analyses identify novel loci associated with n-3 and n-6 polyunsaturated fatty acid levels in Chinese and European-ancestry populations

(2016) Yao Hu et al.   HUMAN MOLECULAR GENETICS

Cholesterol-mediated Degradation of 7-Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis

(2016) Anika V. Prabhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism for HIF-1 activation by cholesterol under normoxia: A redox signaling pathway for liver damage

(2014) Sarit Anavi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

(2014) Anubha Mahajan et al.   NATURE GENETICS

The UPS and downs of cholesterol homeostasis

(2014) Laura J. Sharpe et al.   TRENDS IN BIOCHEMICAL SCIENCES

Palmitic Acid Increases Medial Calcification by Inducing Oxidative Stress

(2013) Mathieu R. Brodeur et al.   JOURNAL OF VASCULAR RESEARCH

Oxysterols in the pathogenesis of major chronic diseases

(2013) Giuseppe Poli et al.   Redox Biology

Associations of erythrocyte palmitoleic acid with adipokines, inflammatory markers, and the metabolic syndrome in middle-aged and older Chinese

(2012) Geng Zong et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Ablation of gp78 in Liver Improves Hyperlipidemia and Insulin Resistance by Inhibiting SREBP to Decrease Lipid Biosynthesis

(2012) Tong-Fei Liu et al.   Cell Metabolism

A Genome-Wide Association Study IdentifiesGRK5andRASGRP1as Type 2 Diabetes Loci in Chinese Hans

(2012) Huaixing Li et al.   DIABETES

Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine

(2012) Chang Xie 谢畅 et al.   JOURNAL OF LIPID RESEARCH

Mechanisms underlying skeletal muscle insulin resistance induced by fatty acids: importance of the mitochondrial function

(2012) Amanda R Martins et al.   Lipids in Health and Disease

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

Cholesterol-Dependent Degradation of Squalene Monooxygenase, a Control Point in Cholesterol Synthesis beyond HMG-CoA Reductase

(2011) Saloni Gill et al.   Cell Metabolism

Electrospray MS/MS reveals extensive and nonspecific oxidation of cholesterol esters in human peripheral vascular lesions

(2011) Patrick M. Hutchins et al.   JOURNAL OF LIPID RESEARCH

Obesity, insulin resistance and free fatty acids

(2011) Guenther Boden   Current Opinion in Endocrinology Diabetes and Obesity

Activation of Glucose-6-phosphate Dehydrogenase Promotes Acute Hypoxic Pulmonary Artery Contraction

(2010) Rakhee S. Gupte et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of NF-κB by Palmitate in Endothelial Cells

(2009) Ezekiel Maloney et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Lipidomic Analysis of Glycerolipid and Cholesteryl Ester Autooxidation Products

(2009) Arnis Kuksis et al.   MOLECULAR BIOTECHNOLOGY

The Cholesterol Absorption Inhibitor Ezetimibe Acts by Blocking the Sterol-Induced Internalization of NPC1L1

(2008) Liang Ge et al.   Cell Metabolism

Identification of putative active site residues of ACAT enzymes

(2008) Akash Das et al.   JOURNAL OF LIPID RESEARCH

A chemical approach for detecting sulfenic acid-modified proteins in living cells

(2008) Khalilah G. Reddie et al.   Molecular BioSystems