标题
Protein–Protein Interactions with Connexin 43: Regulation and Function
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 5, Pages 1428
出版商
MDPI AG
发表日期
2018-05-11
DOI
10.3390/ijms19051428
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The connexin 43 C-terminus: A tail of many tales
- (2018) Edward Leithe et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Spatio-temporal regulation of connexin43 phosphorylation and gap junction dynamics
- (2018) Joell L. Solan et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- The ubiquitin-specific protease USP8 deubiquitinates and stabilizes Cx43
- (2018) Jian Sun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The E3 ubiquitin ligase NEDD4 induces endocytosis and lysosomal sorting of connexin 43 to promote loss of gap junctions
- (2017) Max Z. Totland et al. JOURNAL OF CELL SCIENCE
- Phosphorylation regulates connexin43/ZO-1 binding and release, an important step in gap junction turnover
- (2017) Anastasia F. Thévenin et al. MOLECULAR BIOLOGY OF THE CELL
- Molecular mechanisms regulating formation, trafficking and processing of annular gap junctions
- (2016) Matthias M. Falk et al. BMC CELL BIOLOGY
- Regulation of Connexin43 Function and Expression by Tyrosine Kinase 2
- (2016) Hanjun Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Studies of the Nedd4 WW Domains and Their Selectivity for the Connexin43 (Cx43) Carboxyl Terminus
- (2016) Gaelle Spagnol et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- New protein-protein interactions of mitochondrial connexin 43 in mouse heart
- (2016) Amanda Denuc et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Connexin43 Forms Supramolecular Complexes through Non-Overlapping Binding Sites for Drebrin, Tubulin, and ZO-1
- (2016) Cinzia Ambrosi et al. PLoS One
- The cardiac connexome: Non-canonical functions of connexin43 and their role in cardiac arrhythmias
- (2016) Alejandra Leo-Macias et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Dynamic changes in protein interaction between AKAP95 and Cx43 during cell cycle progression of A549 cells
- (2016) Xiaoxuan Chen et al. Scientific Reports
- Degradation of gap junction connexins is regulated by the interaction with Cx43-interacting protein of 75 kDa (CIP75)
- (2015) Jennifer L. Kopanic et al. BIOCHEMICAL JOURNAL
- Ischaemia-induced autophagy leads to degradation of gap junction protein connexin43 in cardiomyocytes
- (2015) Tania Martins-Marques et al. BIOCHEMICAL JOURNAL
- Gap junctions–guards of excitability
- (2015) Line Waring Stroemlund et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Heart ischemia results in connexin43 ubiquitination localized at the intercalated discs
- (2015) Tânia Martins-Marques et al. BIOCHIMIE
- Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis
- (2015) Wassim A. Basheer et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Interacting Network of the Gap Junction (GJ) Protein Connexin43 (Cx43) is Modulated by Ischemia and Reperfusion in the Heart
- (2015) Tania Martins-Marques et al. MOLECULAR & CELLULAR PROTEOMICS
- Connexin43 phosphorylation by PKC and MAPK signals VEGF-mediated gap junction internalization
- (2015) Wutigri Nimlamool et al. MOLECULAR BIOLOGY OF THE CELL
- Rapid electrical stimulation causes alterations in cardiac intercellular junction proteins of cardiomyocytes
- (2014) Tadamitsu Nakashima et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Super-resolution imaging reveals that loss of the C-terminus of connexin43 limits microtubule plus-end capture and NaV1.5 localization at the intercalated disc
- (2014) Esperanza Agullo-Pascual et al. CARDIOVASCULAR RESEARCH
- Trafficking Highways to the Intercalated Disc: New Insights Unlocking the Specificity of Connexin 43 Localization
- (2014) Shan-Shan Zhang et al. CELL COMMUNICATION AND ADHESION
- Osteoblastic protein tyrosine phosphatases inhibition and connexin 43 phosphorylation by alendronate
- (2014) V. Lezcano et al. EXPERIMENTAL CELL RESEARCH
- AMSH-mediated deubiquitination of Cx43 regulates internalization and degradation of gap junctions
- (2014) Teresa M. Ribeiro-Rodrigues et al. FASEB JOURNAL
- Gap junction regulation by calmodulin
- (2014) Juan Zou et al. FEBS LETTERS
- EGF induces efficient Cx43 gap junction endocytosis in mouse embryonic stem cell colonies via phosphorylation of Ser262, Ser279/282, and Ser368
- (2014) John T. Fong et al. FEBS LETTERS
- Arrhythmogenic cardiomyopathy and Brugada syndrome: Diseases of the connexome
- (2014) Esperanza Agullo-Pascual et al. FEBS LETTERS
- Protein Kinase Cδ-mediated Phosphorylation of Connexin43 Gap Junction Channels Causes Movement within Gap Junctions followed by Vesicle Internalization and Protein Degradation
- (2014) Angela C. Cone et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TC-PTP directly interacts with connexin43 to regulate gap junction intercellular communication
- (2014) Hanjun Li et al. JOURNAL OF CELL SCIENCE
- A PKA-ezrin-Cx43 signaling complex controls gap junction communication and thereby trophoblast cell fusion
- (2014) G. Pidoux et al. JOURNAL OF CELL SCIENCE
- Connexins modulate autophagosome biogenesis
- (2014) Eloy Bejarano et al. NATURE CELL BIOLOGY
- Molecular Structure, Function, and Dynamics of Clathrin-Mediated Membrane Traffic
- (2014) T. Kirchhausen et al. Cold Spring Harbor Perspectives in Biology
- Cross-regulation of Connexin43 and β-catenin influences differentiation of human neural progenitor cells
- (2014) F Rinaldi et al. Cell Death & Disease
- Carboxy terminus and pore-forming domain properties specific to Cx37 are necessary for Cx37-mediated suppression of insulinoma cell proliferation
- (2013) Tasha K. Nelson et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Deletion of the last five C-terminal amino acid residues of connexin43 leads to lethal ventricular arrhythmias in mice without affecting coupling via gap junction channels
- (2013) Indra Lübkemeier et al. BASIC RESEARCH IN CARDIOLOGY
- CIP75 (connexin43-interacting protein of 75 kDa) mediates the endoplasmic reticulum dislocation of connexin43
- (2013) Vivian Su et al. BIOCHEMICAL JOURNAL
- The Canonical WNT2 Pathway and FSH Interact to Regulate Gap Junction Assembly in Mouse Granulosa Cells1
- (2013) Hong-Xing Wang et al. BIOLOGY OF REPRODUCTION
- Super-resolution fluorescence microscopy of the cardiac connexome reveals plakophilin-2 inside the connexin43 plaque
- (2013) Esperanza Agullo-Pascual et al. CARDIOVASCULAR RESEARCH
- Stochastic machines as a colocalization mechanism for scaffold protein function
- (2013) Bin Xue et al. FEBS LETTERS
- Effects of Phosphorylation on the Structure and Backbone Dynamics of the Intrinsically Disordered Connexin43 C-terminal Domain
- (2013) Rosslyn Grosely et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- 14-3-3 facilitates plasma membrane delivery and function of mechanosensitive connexin 43 hemichannels
- (2013) N. Batra et al. JOURNAL OF CELL SCIENCE
- Injury-triggered Akt phosphorylation of Cx43: a ZO-1-driven molecular switch that regulates gap junction size
- (2013) C. A. Dunn et al. JOURNAL OF CELL SCIENCE
- Hypoxia induces connexin 43 dysregulation by modulating matrix metalloproteinases via MAPK signaling
- (2013) Xianghong Wu et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Phosphorylation on Ser-279 and Ser-282 of connexin43 regulates endocytosis and gap junction assembly in pancreatic cancer cells
- (2013) Kristen E. Johnson et al. MOLECULAR BIOLOGY OF THE CELL
- Two tyrosine-based sorting signals in the Cx43 C-terminus cooperate to mediate gap junction endocytosis
- (2013) John T. Fong et al. MOLECULAR BIOLOGY OF THE CELL
- Proteins and Mechanisms Regulating Gap-Junction Assembly, Internalization, and Degradation
- (2013) Anastasia F. Thévenin et al. PHYSIOLOGY
- Connexin43 Functions as a Novel Interacting Partner of Heat Shock Cognate Protein 70
- (2013) Tomoya Hatakeyama et al. Scientific Reports
- Autoregulation of Connexin43 Gap Junction Formation by Internally Translated Isoforms
- (2013) James W. Smyth et al. Cell Reports
- Managing the complexity of communication: regulation of gap junctions by post-translational modification
- (2013) Lene N. Axelsen et al. Frontiers in Pharmacology
- A functional interaction between the MAGUK protein hDlg and the gap junction protein connexin 43 in cervical tumour cells
- (2012) Alasdair I. MacDonald et al. BIOCHEMICAL JOURNAL
- Phosphorylation Controls the Interaction of the Connexin43 C-Terminal Domain with Tubulin and Microtubules
- (2012) Amal Saidi Brikci-Nigassa et al. BIOCHEMISTRY
- Connexin43 ablation in foetal atrial myocytes decreases electrical coupling, partner connexins, and sodium current
- (2012) Thomas Desplantez et al. CARDIOVASCULAR RESEARCH
- MAPK Phosphorylation of Connexin 43 Promotes Binding of Cyclin E and Smooth Muscle Cell Proliferation
- (2012) Scott R. Johnstone et al. CIRCULATION RESEARCH
- Molecular connexin partner remodeling orchestrates connexin traffic: From physiology to pathophysiology
- (2012) Jérôme Gilleron et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Connexin 43 interacts with Bax to regulate apoptosis of pancreatic cancer through a gap junction-independent pathway
- (2012) YAN SUN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Characterization of the Structure and Intermolecular Interactions between the Connexin 32 Carboxyl-terminal Domain and the Protein Partners Synapse-associated Protein 97 and Calmodulin
- (2012) Kelly Stauch et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Smad ubiquitination regulatory factor-2 controls gap junction intercellular communication by modulating endocytosis and degradation of connexin43
- (2012) Tone Aase Fykerud et al. JOURNAL OF CELL SCIENCE
- CASK (LIN2) interacts with Cx43 in wounded skin and their coexpression affects cell migration
- (2012) L. Marquez-Rosado et al. JOURNAL OF CELL SCIENCE
- Coregulation of Multiple Signaling Mechanisms in pp60v-Src-Induced Closure of Cx43 Gap Junction Channels
- (2012) Siddhartha S. Mitra et al. JOURNAL OF MEMBRANE BIOLOGY
- The Noncanonical Functions of Cx43 in the Heart
- (2012) Esperanza Agullo-Pascual et al. JOURNAL OF MEMBRANE BIOLOGY
- Association of Connexin43 with E3 Ubiquitin Ligase TRIM21 Reveals a Mechanism for Gap Junction Phosphodegron Control
- (2012) Vincent C. Chen et al. JOURNAL OF PROTEOME RESEARCH
- Loss of Cadherin-Binding Proteins -Catenin and Plakoglobin in the Heart Leads to Gap Junction Remodeling and Arrhythmogenesis
- (2012) D. Swope et al. MOLECULAR AND CELLULAR BIOLOGY
- Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner
- (2012) Eloy Bejarano et al. MOLECULAR BIOLOGY OF THE CELL
- Norepinephrine inhibits intercellular coupling in rat cardiomyocytes by ubiquitination of connexin43 gap junctions
- (2011) Sarah Mollerup et al. CELL COMMUNICATION AND ADHESION
- Phosphatase-Resistant Gap Junctions Inhibit Pathological Remodeling and Prevent Arrhythmias
- (2011) Benjamin F. Remo et al. CIRCULATION RESEARCH
- Interactions Between Ankyrin-G, Plakophilin-2, and Connexin43 at the Cardiac Intercalated Disc
- (2011) Priscila Y. Sato et al. CIRCULATION RESEARCH
- Abrogation of MMP-9 Gene Protects Against the Development of Retinopathy in Diabetic Mice by Preventing Mitochondrial Damage
- (2011) Renu A. Kowluru et al. DIABETES
- A novel desmocollin-2 mutation reveals insights into the molecular link between desmosomes and gap junctions
- (2011) Katja Gehmlich et al. HEART RHYTHM
- Reduced heterogeneous expression of Cx43 results in decreased Nav1.5 expression and reduced sodium current that accounts for arrhythmia vulnerability in conditional Cx43 knockout mice
- (2011) John A. Jansen et al. HEART RHYTHM
- The perinexus: A new feature of Cx43 gap junction organization
- (2011) Joshua Matthew Rhett et al. HEART RHYTHM
- The large GTPase dynamin2: A new player in connexin 43 gap junction endocytosis, recycling and degradation
- (2011) Jérôme Gilleron et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Activation of Akt, Not Connexin 43 Protein Ubiquitination, Regulates Gap Junction Stability
- (2011) Clarence A. Dunn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Connexin43 interacts with βarrestin: A pre-requisite for osteoblast survival induced by parathyroid hormone
- (2011) Nicoletta Bivi et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1
- (2011) J. Matthew Rhett et al. MOLECULAR BIOLOGY OF THE CELL
- The identification of novel protein, brain-derived integrating factor-1 (BDIF1), which interacts with astrocytic gap junctional protein
- (2011) Takeshi Ito et al. NEUROSCIENCE RESEARCH
- Connexin43 Modulates Cell Polarity and Directional Cell Migration by Regulating Microtubule Dynamics
- (2011) Richard Francis et al. PLoS One
- Ubiquitin-independent Proteasomal Degradation of Endoplasmic Reticulum-localized Connexin43 Mediated by CIP75
- (2010) Vivian Su et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NMR structure note: UBA domain of CIP75
- (2010) Fabien Kieken et al. JOURNAL OF BIOMOLECULAR NMR
- Microtubule +TIPs at a glance
- (2010) A. Akhmanova et al. JOURNAL OF CELL SCIENCE
- Identification of CaMKII Phosphorylation Sites in Connexin43 by High-Resolution Mass Spectrometry
- (2010) Richard Y−C. Huang et al. JOURNAL OF PROTEOME RESEARCH
- Trafficking and Recycling of the Connexin43 Gap Junction Protein during Mitosis
- (2010) Daniela Boassa et al. TRAFFIC
- Connexin43 phosphorylation: structural changes and biological effects
- (2009) Joell L. Solan et al. BIOCHEMICAL JOURNAL
- Connexins: a myriad of functions extending beyond assembly of gap junction channels
- (2009) Hashem A Dbouk et al. Cell Communication and Signaling
- Structural and Molecular Mechanisms of Gap Junction Remodeling in Epicardial Border Zone Myocytes following Myocardial Infarction
- (2009) Fabien Kieken et al. CIRCULATION RESEARCH
- The TSG101 protein binds to connexins and is involved in connexin degradation
- (2009) Tanja Auth et al. EXPERIMENTAL CELL RESEARCH
- Eps15 interacts with ubiquitinated Cx43 and mediates its internalization
- (2009) Henrique Girão et al. EXPERIMENTAL CELL RESEARCH
- Phosphorylation of connexin43 on serine 306 regulates electrical coupling
- (2009) Kristina Procida et al. HEART RHYTHM
- Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins
- (2009) Francisco J. del Castillo et al. HUMAN MOLECULAR GENETICS
- Activator of G Protein Signaling 8 (AGS8) Is Required for Hypoxia-induced Apoptosis of Cardiomyocytes
- (2009) Motohiko Sato et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
- (2009) E. Leithe et al. JOURNAL OF CELL SCIENCE
- ERp29 Restricts Connexin43 Oligomerization in the Endoplasmic Reticulum
- (2009) Shamie Das et al. MOLECULAR BIOLOGY OF THE CELL
- Connexin43 interacts with Caveolin-3 in the heart
- (2009) Limei Liu et al. MOLECULAR BIOLOGY REPORTS
- Connexin 43 and plakophilin-2 as a protein complex that regulates blood-testis barrier dynamics
- (2009) M. W. M. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The gap junction proteome and its relationship to disease
- (2009) Dale W. Laird TRENDS IN CELL BIOLOGY
- Structural Changes in the Carboxyl Terminus of the Gap Junction Protein Connexin40 Caused by the Interaction with c-Src and Zonula Occludens-1
- (2008) Denis Bouvier et al. CELL COMMUNICATION AND ADHESION
- Connexin43 in LA-25 Cells with Active v-src Is Phosphorylated on Y247, Y265, S262, S279/282, and S368 via Multiple Signaling Pathways
- (2008) Joell L. Solan et al. CELL COMMUNICATION AND ADHESION
- Molecular reorganization of Cx43, Zo-1 and Src complexes during the endocytosis of gap junction plaques in response to a non-genomic carcinogen
- (2008) J. Gilleron et al. JOURNAL OF CELL SCIENCE
- Phosphatidylinositol-bisphosphate regulates intercellular coupling in cardiac myocytes
- (2008) Johannes P. Hofgaard et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Regulation of synaptic inhibition by phospho-dependent binding of the AP2 complex to a YECL motif in the GABAA receptor 2 subunit
- (2008) J. T. Kittler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Caveolin-1 and -2 Interact with Connexin43 and Regulate Gap Junctional Intercellular Communication in Keratinocytes
- (2007) Stéphanie Langlois et al. MOLECULAR BIOLOGY OF THE CELL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started