NFkB is activated by multiple mechanisms in hairy cell leukemia

Requirement for CDK6 in MLL-rearranged acute myeloid leukemia

(2014) T. Placke et al.   BLOOD

Cancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitors

(2014) Laura Tornatore et al.   CANCER CELL

NF-κB pathways in hematological malignancies

(2014) Chiara Gasparini et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cyclin-Dependent Kinase 6 Is a Chromatin-Bound Cofactor for NF-κB-Dependent Gene Expression

(2014) Katja Handschick et al.   MOLECULAR CELL

DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier

(2014) Margarida A. Santos et al.   NATURE

Hairy cell leukemia: short review, today’s recommendations and outlook

(2014) V Maevis et al.   Blood Cancer Journal

I B-  controls the constitutive NF- B target gene network and survival of ABC DLBCL

(2013) H. Nogai et al.   BLOOD

RAF Inhibitors Activate the MAPK Pathway by Relieving Inhibitory Autophosphorylation

(2013) Matthew Holderfield et al.   CANCER CELL

Constant activation of the RAF-MEK-ERK pathway as a diagnostic and therapeutic target in hairy cell leukemia

(2013) E. Tiacci et al.   HAEMATOLOGICA

II. Therapy of DLBCL based on genomics

(2013) Louis M. Staudt   HEMATOLOGICAL ONCOLOGY

Distinguishing hairy cell leukemia variant from hairy cell leukemia: Development and validation of diagnostic criteria

(2013) Haipeng Shao et al.   LEUKEMIA RESEARCH

Genetic aberrations of signaling pathways in lymphomagenesis: Revelations from next generation sequencing studies

(2013) Davide Rossi et al.   SEMINARS IN CANCER BIOLOGY

Toll-Like Receptor Signaling

(2013) K.-H. Lim et al.   Cold Spring Harbor Perspectives in Biology

Absence of BRAF-V600E in the human cell lines BONNA-12, ESKOL, HAIR-M, and HC-1 questions their origin from hairy cell leukemia

(2012) E. Tiacci et al.   BLOOD

NF-κB function in B lymphocytes

(2012) Mary Kaileh et al.   IMMUNOLOGICAL REVIEWS

DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out

(2012) Kevin W. McCool et al.   IMMUNOLOGICAL REVIEWS

Roles of BCL6 in normal and transformed germinal center B cells

(2012) Katia Basso et al.   IMMUNOLOGICAL REVIEWS

Hairy cell leukemia cell lines expressing annexin A1 and displaying B-cell receptor signals characteristic of primary tumor cells lack the signature BRAF mutation to reveal unrepresentative origins

(2012) N J Weston-Bell et al.   LEUKEMIA

EGFR-Induced and PKCε Monoubiquitylation-Dependent NF-κB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis

(2012) Weiwei Yang et al.   MOLECULAR CELL

CUX1 transcription factor is required for optimal ATM/ATR-mediated responses to DNA damage

(2012) Charles Vadnais et al.   NUCLEIC ACIDS RESEARCH

Cyclin-Dependent Kinase 6 Phosphorylates NF-κB P65 at Serine 536 and Contributes to the Regulation of Inflammatory Gene Expression

(2012) Holger Buss et al.   PLoS One

Both variant and IGHV4-34-expressing hairy cell leukemia lack the BRAF V600E mutation

(2011) L. Xi et al.   BLOOD

The kinetochore protein Bub1 participates in the DNA damage response

(2011) Chunying Yang et al.   DNA REPAIR

Activation of Paired-homeobox gene PITX1 by del(5)(q31) in T-cell acute lymphoblastic leukemia

(2011) Stefan Nagel et al.   LEUKEMIA & LYMPHOMA

Transcriptional deregulation of homeobox gene ZHX2 in Hodgkin lymphoma

(2011) Stefan Nagel et al.   LEUKEMIA RESEARCH

BRAFMutations in Hairy-Cell Leukemia

(2011) Enrico Tiacci et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genomic and Gene Expression Profiling Defines Indolent Forms of Mantle Cell Lymphoma

(2010) V. Fernandez et al.   CANCER RESEARCH

γH2AX: a sensitive molecular marker of DNA damage and repair

(2010) L-J Mah et al.   LEUKEMIA

Polycomb repressor complex 2 regulates HOXA9 and HOXA10, activating ID2 in NK/T-cell lines

(2010) Stefan Nagel et al.   Molecular Cancer

Oncogenic Activation of NF- B

(2010) L. M. Staudt   Cold Spring Harbor Perspectives in Biology

VH4-34+ hairy cell leukemia, a new variant with poor prognosis despite standard therapy

(2009) E. Arons et al.   BLOOD

Characterisation of hairy cell leukaemia by tiling resolution array-based comparative Genome hybridisation: a series of 13 cases and review of the literature

(2009) Ann Nordgren et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

TNFAIP3(A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma

(2009) Roland Schmitz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma

(2009) Mara Compagno et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

TIPE2, a Negative Regulator of Innate and Adaptive Immunity that Maintains Immune Homeostasis

(2008) Honghong Sun et al.   CELL

Origin and pathogenesis of nodular lymphocyte–predominant Hodgkin lymphoma as revealed by global gene expression analysis

(2008) Verena Brune et al.   JOURNAL OF EXPERIMENTAL MEDICINE