标题
Requirement for CDK6 in MLL-rearranged acute myeloid leukemia
作者
关键词
-
出版物
BLOOD
Volume 124, Issue 1, Pages 13-23
出版商
American Society of Hematology
发表日期
2014-04-25
DOI
10.1182/blood-2014-02-558114
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Cyclin-Dependent Kinase 6 Is a Chromatin-Bound Cofactor for NF-κB-Dependent Gene Expression
- (2014) Katja Handschick et al. MOLECULAR CELL
- A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis
- (2013) Karoline Kollmann et al. CANCER CELL
- Epigenetic Roles of MLL Oncoproteins Are Dependent on NF-κB
- (2013) Hsu-Ping Kuo et al. CANCER CELL
- Phase II Trial of the CDK4 Inhibitor PD0332991 in Patients With Advanced CDK4-Amplified Well-Differentiated or Dedifferentiated Liposarcoma
- (2013) Mark A. Dickson et al. JOURNAL OF CLINICAL ONCOLOGY
- The MLL recombinome of acute leukemias in 2013
- (2013) C Meyer et al. LEUKEMIA
- Cancer's true breakthroughs
- (2013) Elie Dolgin NATURE MEDICINE
- Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma
- (2012) J. P. Leonard et al. BLOOD
- Cyclin dependent kinases in cancer
- (2012) Miriam Canavese et al. CANCER BIOLOGY & THERAPY
- The Histone Demethylase KDM1A Sustains the Oncogenic Potential of MLL-AF9 Leukemia Stem Cells
- (2012) William J. Harris et al. CANCER CELL
- A Missing Link in Genotype-Directed Cancer Therapy
- (2012) René Bernards CELL
- Molecular pathogenesis of mantle cell lymphoma
- (2012) Pedro Jares et al. JOURNAL OF CLINICAL INVESTIGATION
- CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling
- (2012) Katrin Faber et al. JOURNAL OF CLINICAL INVESTIGATION
- Deregulated Expression of EVI1 Defines a Poor Prognostic Subset of MLL-Rearranged Acute Myeloid Leukemias: A Study of the German-Austrian Acute Myeloid Leukemia Study Group and the Dutch-Belgian-Swiss HOVON/SAKK Cooperative Group
- (2012) Stefan Gröschel et al. JOURNAL OF CLINICAL ONCOLOGY
- Inhibition of cyclin-dependent kinase 6 suppresses cell proliferation and enhances radiation sensitivity in medulloblastoma cells
- (2012) Susan L. Whiteway et al. JOURNAL OF NEURO-ONCOLOGY
- How to manage acute promyelocytic leukemia
- (2012) J-Q Mi et al. LEUKEMIA
- Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia
- (2012) Jolanta Grembecka et al. Nature Chemical Biology
- Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma
- (2012) Lawrence N Kwong et al. NATURE MEDICINE
- MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome
- (2011) Q.-f. Wang et al. BLOOD
- CDK6 kinase activity is required for thymocyte development
- (2011) M. G. Hu et al. BLOOD
- Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation
- (2011) S. Y. Jo et al. BLOOD
- Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor
- (2011) Scott R. Daigle et al. CANCER CELL
- MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1L
- (2011) Kathrin M. Bernt et al. CANCER CELL
- CBX8, a Polycomb Group Protein, Is Essential for MLL-AF9-Induced Leukemogenesis
- (2011) Jiaying Tan et al. CANCER CELL
- Essential role of DOT1L in maintaining normal adult hematopoiesis
- (2011) Anh T Nguyen et al. CELL RESEARCH
- Phase I, Dose-Escalation Trial of the Oral Cyclin-Dependent Kinase 4/6 Inhibitor PD 0332991, Administered Using a 21-Day Schedule in Patients with Advanced Cancer
- (2011) K. T. Flaherty et al. CLINICAL CANCER RESEARCH
- RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
- (2011) Johannes Zuber et al. NATURE
- Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
- (2011) Mark A. Dawson et al. NATURE
- RGB marking facilitates multicolor clonal cell tracking
- (2011) Kristoffer Weber et al. NATURE MEDICINE
- Towards systematic functional characterization of cancer genomes
- (2011) Jesse S. Boehm et al. NATURE REVIEWS GENETICS
- Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes
- (2011) D. Biswas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials
- (2010) D. Grimwade et al. BLOOD
- A Synthetic Lethal Interaction between K-Ras Oncogenes and Cdk4 Unveils a Therapeutic Strategy for Non-small Cell Lung Carcinoma
- (2010) Marta Puyol et al. CANCER CELL
- β-Catenin Mediates the Establishment and Drug Resistance of MLL Leukemic Stem Cells
- (2010) Jenny Yeung et al. CANCER CELL
- Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom)
- (2010) M. Mohan et al. GENES & DEVELOPMENT
- Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM
- (2010) W. R. Wiedemeyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Wnt/ -Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML
- (2010) Y. Wang et al. SCIENCE
- Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet
- (2009) H. Dohner et al. BLOOD
- A Requirement for Cyclin-Dependent Kinase 6 in Thymocyte Development and Tumorigenesis
- (2009) M. G. Hu et al. CANCER RESEARCH
- Synthetic Lethal Interaction between Oncogenic KRAS Dependency and STK33 Suppression in Human Cancer Cells
- (2009) Claudia Scholl et al. CELL
- The molecular biology of mixed lineage leukemia
- (2009) R. K. Slany HAEMATOLOGICA
- Prognostic Factors in Adult Patients up to 60 Years Old With Acute Myeloid Leukemia and Translocations of Chromosome Band 11q23: Individual Patient Data–Based Meta-Analysis of the German Acute Myeloid Leukemia Intergroup
- (2009) Jürgen Krauter et al. JOURNAL OF CLINICAL ONCOLOGY
- Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
- (2009) David A. Barbie et al. NATURE
- Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors
- (2009) Robert H Kutner et al. Nature Protocols
- HOXA9 is required for survival in human MLL-rearranged acute leukemias
- (2008) J. Faber et al. BLOOD
- A role for MEIS1 in MLL-fusion gene leukemia
- (2008) A. R. Kumar et al. BLOOD
- Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia
- (2008) M. G. Guenther et al. GENES & DEVELOPMENT
- Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy
- (2008) Zhong Wang et al. NATURE
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